LYN antibody
- CAS No.
- Chemical Name:
- LYN antibody
- Synonyms
- LYN antibody
- CBNumber:
- CB75652269
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
LYN antibody price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biorbyt Ltd | orb254643 | LYN antibody | 50μl | $350 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb254643 | LYN antibody | 100μl | $480 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb252947 | LYN Antibody | 100μl | $360 | 2026-05-06 | Buy | |
| Biorbyt Ltd | orb6338 | Lyn antibody Affinity purified by Protein A | 5μg(Trial Size) | $66.3 | 2021-12-16 | Buy | |
| Biorbyt Ltd | orb6338 | Lyn antibody Affinity purified by Protein A | 20μg(Trial Size) | $141.1 | 2021-12-16 | Buy |
LYN antibody Chemical Properties,Uses,Production
Source
Rabbit
Reactivity
Human;Mouse;Rat
Background
Lyn, one of the Src family members, is predominantly expressed in hematopoietic cells. Two tyrosine residues have been reported to play a crucial role in the regulation of protein tyrosine kinases of the Src family. Autophosphorylation of Tyr396, located in the catalytic domain, correlates with enzyme activation. Csk-mediated phosphorylation of the carboxy-terminal Tyr507 inactivates the kinase. Tyrosine phosphorylation and activation of Lyn occurs upon association with cell surface receptors such as the B cell Ag receptor and CD40. Studies using knockout mice have shown that the net effect of Lyn deficiency is to render B cells hypersensitive to BCR stimulation, suggesting that the most critical role for Lyn in vivo is in the down-regulation of B cell responses. Lyn is also involved in controlling the migration and development of specific B cell populations.
References
[1] Yamanashi, Y. et al. (1989) Proc. Natl. Acad. Sci. USA 86, 6538-6542.
[2] Yamanashi, Y. et al. (1991) Science 251, 192-194.
[3] Burkhardt, A.L. et al. (1991) Proc. Natl. Acad. Sci. USA 88, 7410-7414.
[4] Ren, C.L. et al. (1994) J. Exp. Med. 179, 673-680.
[5] Wang, J. et al. (1996) J Exp Med 184, 831-8.
[6] Chan, V.W. et al. (1997) Immunity 7, 69-81.
[7] Hibbs, M.L. et al. (1995) Cell 83, 301-11.
[8] Seo, S. et al. (2001) J Immunol 166, 3710-6.
LYN antibody Preparation Products And Raw materials
Raw materials
Preparation Products
LYN antibody Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Ipodix Biotechnology Co.,Ltd. | 18007124176 19384116026 | 2706668885@qq.com | China | 4987 | 58 |
| Supplier | Advantage |
|---|---|
| Hubei Ipodix Biotechnology Co.,Ltd. | 58 |
