ChemicalBook >> CAS DataBase List >>(2,5-dioxopyrrolidin-1-yl) (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoate

(2,5-dioxopyrrolidin-1-yl) (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoate

(2,5-dioxopyrrolidin-1-yl) (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoate structure

CAS No.: 182410-73-7

Chemical Name:: (2,5-dioxopyrrolidin-1-yl) (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoate

Synonyms: D-Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 2,5-dioxo-1-pyrrolidinyl ester;(2,5-dioxopyrrolidin-1-yl) (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoate

CBNumber:: CB75839356

Molecular Formula:: C28H24N2O6

Molecular Weight:: 484.5

MDL Number:

MOL File:: 182410-73-7.mol

MSDS File:: SDS

Last updated:2025-04-17 18:22:24

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(2,5-dioxopyrrolidin-1-yl) (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoate Properties

Density	1.39±0.1 g/cm3(Predicted)
pka	10.14±0.46(Predicted)

(2,5-dioxopyrrolidin-1-yl) (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoate Chemical Properties,Uses,Production

Uses

Fmoc-(D-Phe)-Osu is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC 50

Cleavable Linker

References

[1] Geoffrey C. Winters, et al. Sulfonamide-containing linkage systems for drug conjugates. WO2015095953A1.

(2,5-dioxopyrrolidin-1-yl) (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoate Preparation Products And Raw materials

Raw materials

Preparation Products

(2,5-dioxopyrrolidin-1-yl) (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoate Suppliers

Global( 3)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Chongqing jooe co., ltd	+undefined86-15223382610	info@jooe.com	China	15976	58
Binhai gill polypeptide co. LTD	021-61263389 13524856427	Joetang@glschina.com	China	9932	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29430	58

Supplier	Advantage
Chongqing jooe co., ltd	58
Binhai gill polypeptide co. LTD	58
TargetMol Chemicals Inc.	58

(2,5-dioxopyrrolidin-1-yl) (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenylpropanoate D-Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 2,5-dioxo-1-pyrrolidinyl ester 182410-73-7