Neuromedin U-25 (human) (trifluoroacetate salt)
- CAS No.
- Chemical Name:
- Neuromedin U-25 (human) (trifluoroacetate salt)
- Synonyms
- Neuromedin U-25 (human) (trifluoroacetate salt)
- CBNumber:
- CB76197266
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Neuromedin U-25 (human) (trifluoroacetate salt) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 17617 | Neuromedin U-25 (human) (trifluoroacetate salt) ≥95% | 500μg | $132 | 2026-04-30 | Buy | |
| Cayman Chemical | 17617 | Neuromedin U-25 (human) (trifluoroacetate salt) ≥95% | 1mg | $198 | 2026-04-30 | Buy | |
| Cayman Chemical | 17617 | Neuromedin U-25 (human) (trifluoroacetate salt) ≥95% | 5mg | $786 | 2026-04-30 | Buy |
Neuromedin U-25 (human) (trifluoroacetate salt) Chemical Properties, Uses, Production
Description
Neuromedin U (NMU) is a neuropeptide first demonstrated to drive smooth muscle contraction. Translated as a 174 amino acid propeptide, NMU is cleaved to different lengths in different animals. It has diverse receptor-mediated roles in vivo, as it regulates feeding, vasoconstriction, nociception, and bone remodeling and contributes to obesity, cancer and septic shock. NMU-25 is the active form of NMU in humans. It binds with high affinity to receptors on human left ventricle and coronary artery (KDs = 0.26 and 0.11 nM, respectively), eliciting endothelium-independent vasoconstriction. NMU-25 also suppresses glucose-stimulated insulin secretion in human islets, and this effect is lost in NMU R165W mutants, resulting in early-onset obesity.
References
[1] JD MITCHELL AP D JJ Maguire. Emerging pharmacology and physiology of neuromedin U and the structurally related peptide neuromedin S[J]. British Journal of Pharmacology, 2009, 158 1: 87-103. DOI: 10.1111/j.1476-5381.2009.00252.x
[2] HANNAH C GREENWOOD K G M Stephen R Bloom. Peptides and their potential role in the treatment of diabetes and obesity.[J]. Review of Diabetic Studies, 2011, 8 3: 355-368. DOI: 10.1900/rds.2011.8.355
[3] J. MITCHELL. Expression and vasoconstrictor function of anorexigenic peptides neuromedin U-25 and S in the human cardiovascular system.[J]. Cardiovascular Research, 2008, 81 2 1: 353-361. DOI: 10.1093/cvr/cvn302
[4] RONALD W ALFA. Suppression of Insulin Production and Secretion by a Decretin Hormone.[J]. Cell metabolism, 2018: 479. DOI: 10.1016/j.cmet.2018.01.003
Neuromedin U-25 (human) (trifluoroacetate salt) Preparation Products And Raw materials
Raw materials
Preparation Products
Neuromedin U-25 (human) (trifluoroacetate salt) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| BOC Sciences | 58 |
View Latest Price from Neuromedin U-25 (human) (trifluoroacetate salt) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-22 | Neuromedin U-25 (human) (trifluoroacetate salt) | $652.00-2580.00 | 10g | TargetMol Chemicals Inc. | |||
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2025-12-22 | Neuromedin U-25 (human) (trifluoroacetate salt) | 10g | TargetMol Chemicals Inc. |
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- Neuromedin U-25 (human) (trifluoroacetate salt)
- $652.00-2580.00
- TargetMol Chemicals Inc.
-
- Neuromedin U-25 (human) (trifluoroacetate salt)
- TargetMol Chemicals Inc.
