5-Bromo-1H-benzimidazole-2-amine
- CAS No.
- 791595-74-9
- Chemical Name:
- 5-Bromo-1H-benzimidazole-2-amine
- Synonyms
- 6-bromo-1H-benzo[d]imidazol-2-amine;2-Amino-5-bromobenzimidazole;2-amino-6-bromo benzimidazole;5-Bromo-1H-benzimidazol-2-amine;6-bromo-1H-Benzimidazol-2-amine;2-Amino-6-Bromo-1H-benzimidaZole;2-AMino-5-BroMo-1H-BenziMidazole;5-Bromo-1H-benzimidazole-2-amine;1H-Benzimidazol-2-amine, 6-bromo-;6-bromo-1H-1,3-benzodiazol-2-amine
- CBNumber:
- CB7667181
- Molecular Formula:
- C7H6BrN3
- Molecular Weight:
- 212.05
- MDL Number:
- MFCD06659788
- MOL File:
- 791595-74-9.mol
- MSDS File:
- SDS
| Boiling point | 425.2±37.0 °C(Predicted) |
|---|---|
| Density | 1.867±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C(protect from light) |
| form | solid |
| pka | 10.16±0.10(Predicted) |
| Appearance | Light brown to brown Solid |
| InChI | 1S/C7H6BrN3/c8-4-1-2-5-6(3-4)11-7(9)10-5/h1-3H,(H3,9,10,11) |
| InChIKey | YLKNNXAMJFCCPY-UHFFFAOYSA-N |
| SMILES | NC1=NC2=C(C=CC(Br)=C2)N1 |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335-H302 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362 |
| RIDADR | 2811 |
| HazardClass | 6.1 |
| PackingGroup | Ⅲ |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral |
5-Bromo-1H-benzimidazole-2-amine price More Price(59)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS42790 | 5-Bromo-1H-benzo[d]imidazol-2-amine 97% | 791595-74-9 | 1g | $74 | 2026-06-04 | Buy |
| Activate Scientific | AS42790 | 5-Bromo-1H-benzo[d]imidazol-2-amine 97% | 791595-74-9 | 5g | $258 | 2026-06-04 | Buy |
| Activate Scientific | AS42790 | 5-Bromo-1H-benzo[d]imidazol-2-amine 97% | 791595-74-9 | 25g | $835 | 2026-06-04 | Buy |
| Matrix Scientific | 121476 | 5-Bromo-1H-benzo[d]imidazol-2-amine | 791595-74-9 | 1.00g | $785 | 2026-05-18 | Buy |
| Matrix Scientific | 121476 | 5-Bromo-1H-benzo[d]imidazol-2-amine | 791595-74-9 | 5.00g | $1265 | 2026-05-18 | Buy |
5-Bromo-1H-benzimidazole-2-amine Chemical Properties, Uses, Production
Synthesis
506-68-3
1575-37-7
791595-74-9
Step A: Synthesis of 5-bromo-1H-benzimidazol-2-amine [00400] 4-Bromo-1,2-benzenediamine (4 g, 21.39 mmol) was dissolved in methanol (20 mL) to form a dark brown solution. Cyanogen bromide (2.492 g, 23.52 mmol) was added to this solution. The reaction was exothermic and the methanol began to boil after a few seconds. After 5 minutes of reaction, the reaction mixture was diluted with ethyl acetate (100 mL) and washed sequentially with saturated aqueous sodium bicarbonate solution (100 mL) and saturated sodium chloride solution (100 mL). After concentrating the organic layer to a few mL, it was purified by silica gel column chromatography (0-20% methanol/ethyl acetate gradient elution) to afford 5-bromo-1H-benzimidazol-2-amine (3.9 g, 18.39 mmol, 86% yield) as a black solid. 1H NMR (400 MHz, DMSO-d6) δ ppm: 6.47 (br.s., 2H), 6.94-7.00 (m, 1H), 7.01-7.06 (m, 1H), 7.23 (d, J = 1.85 Hz, 1H), 8.70-11.33 (m, 1H); ES LC-MS m/z = 212.2 (Br 79, M + H)+, ES LC-MS m/z = 214.2 (Br 81, M + H)+.
References
[1] Angewandte Chemie - International Edition, 2012, vol. 51, # 21, p. 5226 - 5229
[2] Patent: US2013/136782, 2013, A1. Location in patent: Paragraph 0216; 0217
[3] Patent: WO2012/174312, 2012, A2. Location in patent: Page/Page column 283-284
[4] Patent: WO2008/42282, 2008, A2. Location in patent: Page/Page column 219-220
[5] Advanced Synthesis and Catalysis, 2018, vol. 360, # 10, p. 1943 - 1948
5-Bromo-1H-benzimidazole-2-amine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| ShangHai YuanYe Biotechnology Co., Ltd. | 15026964105 | shyysw007@163.com | China | 4998 | 60 |
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 3996 | 55 |
| Shanghai potentpharm CO.,Ltd | 13524892556 | sales-cn@potentpharm.com | China | 1011 | 55 |
| DanYang Ruihui Chemical Co.,Ltd | 0511-86883198 | sales@rhchemical.com | China | 33 | 58 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| HBCChem, Inc. | +1-510-219-6317 | sales@hbcchem.com | United States | 10628 | 60 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| ShangHai KenEn Chemical Technology Co., Ltd. | 13120367189;18621755571 | mychess007@163.com | China | 1994 | 55 |
| Mashilabs (Shanghai) Co.,Ltd. | 19916721580 | mafarm@126.com | China | 4534 | 58 |
View Latest Price from 5-Bromo-1H-benzimidazole-2-amine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-10 | 5-BROMO-1H-BENZIMIDAZOLE-2-AMINE
791595-74-9
|
$1.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- 5-BROMO-1H-BENZIMIDAZOLE-2-AMINE
791595-74-9
- $1.00
- 99%
- Career Henan Chemical Co
