5-Chloro-1H-indazole-3-carboxylic acid
- CAS No.
- 1077-95-8
- Chemical Name:
- 5-Chloro-1H-indazole-3-carboxylic acid
- Synonyms
- 5-CHLORO-3-INDAZOLECARBOXYLIC ACID;5-CHLORO-3-INDOZOLE-CARBOXYLIC ACID;5-chloro-1H-indazol-3-carboxylic acid;5-chloro-1h-indazole-3-carboxylic acod;5-CHLORO-1H-INDAZOLE-3-CARBOXYLIC ACID;5-CHLORO-3-(1H)INDAZOLE CARBOXYLIC ACID;1H-Indazole-3-carboxylic acid, 5-chloro-;5-Chloro-1H-indazole-3-carboxylic acid ,97%
- CBNumber:
- CB7675256
- Molecular Formula:
- C8H5ClN2O2
- Molecular Weight:
- 196.59
- MDL Number:
- MFCD02326712
- MOL File:
- 1077-95-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P305+P351+P338 |
| Risk Statements | 22-36 |
| Safety Statements | 26 |
| HS Code | 29339900 |
5-Chloro-1H-indazole-3-carboxylic acid price More Price(57)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 234077 | 5-Chloro-1H-indazole-3-carboxylic acid ≥95% (HPLC) ≥95%(HPLC) | 1077-95-8 | 250mg | $252 | 2026-06-03 | Buy |
| Usbiological | 234077 | 5-Chloro-1H-indazole-3-carboxylic acid ≥95% (HPLC) ≥95%(HPLC) | 1077-95-8 | 1g | $347 | 2026-06-03 | Buy |
| Usbiological | 234077 | 5-Chloro-1H-indazole-3-carboxylic acid ≥95% (HPLC) ≥95%(HPLC) | 1077-95-8 | 5g | $874 | 2026-06-03 | Buy |
| Chem-Impex | 17499 | 5-Chloro-1H-indazole-3-carboxylic acid ≥95%(HPLC) | 1077-95-8 | 250MG | $65.4 | 2026-05-19 | Buy |
| Chem-Impex | 17499 | 5-Chloro-1H-indazole-3-carboxylic acid ≥95%(HPLC) | 1077-95-8 | 1G | $138.61 | 2026-05-19 | Buy |
5-Chloro-1H-indazole-3-carboxylic acid Chemical Properties,Uses,Production
Application
5-Chloro-1H-indazole-3-carboxylic acid is an important pharmaceutical intermediate used to construct the core of active drug molecules.
Chemical Properties
Light yellow solid
Synthesis
1H-indazole-3-carboxylic acid was dissolved in anhydrous acetic acid in a three-necked flask, heated and stirred. After the substrate was dissolved and clarified, phosphorus oxychloride was dissolved in anhydrous acetic acid and slowly added dropwise. In an oil bath at 90°C, the mixture was condensed back into the chemical book and reacted for 14 hours. After the reaction was complete, a white precipitate was produced. It was cooled in an ice bath, vacuum filtered, and the solid was washed with ethyl acetate first and then with ether to obtain 5-Chloro-1H-indazole-3-carboxylic acid.
References
[1] Patent: WO2005/14554, 2005, A1. Location in patent: Page/Page column 60-61
[2] Patent: EP2565192, 2013, A1. Location in patent: Paragraph 0356
[3] Journal of Medicinal Chemistry, 2013, vol. 56, # 15, p. 6259 - 6272
[4] Patent: WO2015/103317, 2015, A1. Location in patent: Page/Page column 97
5-Chloro-1H-indazole-3-carboxylic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4263 | 65 | |
| Wuhan TCASChem Technology Co., Ltd. | 027-86697669 13986148687 | sales@tcaschem.com | China | 3993 | 55 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| Shanghai Keepontech Co.,Ltd | 021-54849683 13601642561 | sales@keepontech.com | China | 997 | 59 |
| Shanghai Sheepchem Co., Ltd. | +86 (21) 6715-7650 | sheepchem@163.com | China | 993 | 60 |
| Runpharm Technology Limited | 18171398856 2968382473 | service@runpharm.com | China | 716 | 55 |
View Lastest Price from 5-Chloro-1H-indazole-3-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-08-06 | 5-CHLORO-1H-INDAZOLE-3-CARBOXYLIC ACID
1077-95-8
|
$1.00 | 1KG | 98% | 10KG | Career Henan Chemical Co |
-
- 5-CHLORO-1H-INDAZOLE-3-CARBOXYLIC ACID
1077-95-8
- $1.00
- 98%
- Career Henan Chemical Co
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