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ChemicalBook >> CAS DataBase List >>3,5-Dimethoxypyridine-4-carboxaldehyde

3,5-Dimethoxypyridine-4-carboxaldehyde

3,5-Dimethoxypyridine-4-carboxaldehyde Structure
3,5-Dimethoxypyridine-4-carboxaldehyde structure
CAS No.
204862-70-4
Chemical Name:
3,5-Dimethoxypyridine-4-carboxaldehyde
Synonyms
3,5-Dimethoxyisonicotinaldehyde;3,5-dimethoxypyridine-4-carbaldehyde;3,5-Dimethoxypyridine-4-carboxaldehyde;3,5-dimethoxypyridine-4-methylaldehyde;3,5-Dimethoxy-4-pyridinecarboxaldehyde;4-Pyridinecarboxaldehyde, 3,5-dimethoxy-;2-forMyl-3,5-diMethoxypyridine-4-carboxylic acid
CBNumber:
CB7680234
Molecular Formula:
C8H9NO3
Molecular Weight:
167.16
MDL Number:
MFCD06410671
MOL File:
204862-70-4.mol
MSDS File:
SDS
Last updated:2026-09-12 18:55:05
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3,5-Dimethoxypyridine-4-carboxaldehyde Properties

Boiling point 319.6±37.0 °C(Predicted)
Density 1.174
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 2.09±0.10(Predicted)
Appearance White to off-white Solid

3,5-Dimethoxypyridine-4-carboxaldehyde price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS44063 3,5-Dimethoxyisonicotinaldehyde 95% 204862-70-4 100mg $164 2026-06-04 Buy
Activate Scientific AS44063 3,5-Dimethoxyisonicotinaldehyde 95% 204862-70-4 250mg $211 2026-06-04 Buy
Activate Scientific AS44063 3,5-Dimethoxyisonicotinaldehyde 95% 204862-70-4 1g $527 2026-06-04 Buy
Activate Scientific AS44063 3,5-Dimethoxyisonicotinaldehyde 95% 204862-70-4 5g $1764 2026-06-04 Buy
Matrix Scientific 309582 3,5-Dimethoxyisonicotinaldehyde 204862-70-4 100.00mg $121 2026-05-19 Buy
Product number Packaging Price Buy
AS44063 100mg $164 Buy
AS44063 250mg $211 Buy
AS44063 1g $527 Buy
AS44063 5g $1764 Buy
309582 100.00mg $121 Buy

3,5-Dimethoxypyridine-4-carboxaldehyde Chemical Properties, Uses, Production

Synthesis

3,5-Dimethoxypyridine

18677-48-0

N,N-Dimethylformamide

68-12-2

3,5-DIMETHOXYPYRIDINE-4-CARBOXALDEHYDE

204862-70-4

To a solution of 3,5-dimethoxypyridine (3.6 g, 25.90 mmol, 1 eq.) in tetrahydrofuran (THF, 80 mL) was slowly added n-butyllithium (BuLi, 3M hexane solution, 13.0 mL, 38.85 mmol, 1.5 eq.) at -20 °C. The reaction mixture was slowly warmed to 0 °C and stirred at this temperature for 30 minutes. Subsequently, the reaction system was cooled to -78 °C and N,N-dimethylformamide (DMF, 3.8 g, 51.8 mmol, 2 eq.) was added dropwise. The reaction mixture was gradually warmed to 0 °C and the reaction was quenched with saturated aqueous ammonium chloride (NH4Cl) and diluted with ethyl acetate (EtOAc). The aqueous phase was extracted twice with ethyl acetate (EtOAc). The organic phases were combined, washed with saturated saline (brine), dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography using a solvent mixture of ethyl acetate (EtOAc) and hexane as eluent to afford 3,5-dimethoxypyridine-4-carbaldehyde (2.7 g, 62% yield) as a yellow solid. Low resolution mass spectrometry (LRMS) showed (M+H)+ m/z 168.1.

References

[1] Patent: WO2013/102145, 2013, A1. Location in patent: Paragraph 0316
[2] Patent: US2015/344483, 2015, A1. Location in patent: Paragraph 0584; 0585
[3] ACS Medicinal Chemistry Letters, 2017, vol. 8, # 3, p. 321 - 326
[4] Patent: WO2007/30582, 2007, A2. Location in patent: Page/Page column 89

3,5-Dimethoxypyridine-4-carboxaldehyde Preparation Products And Raw materials

Raw materials

3,5-Dimethoxypyridine N,N-Dimethylformamide n-Butyllithium Tetrahydrofuran

Preparation Products

3,5-Dimethoxypyridine-4-carboxaldehyde Suppliers

Global Suppliers ( 60)
Supplier Tel Email Country ProdList Advantage
Heterochem 027-88041443 13072715837 sales@hetero-chem.com China 695 58
Chengdu Ai Keda Chemical Technology Co., Ltd. 4008-755-333 18080918076 800078821@qq.com China 9706 55
SynAsst Chemical. 021-60343070 China 12731 55
Shanghai Raise Chemical Technology Co.,Ltd +86-021-50935922 China 7854 55
Hebei Summedchem Co.,Ltd 0319-5801333-8008 15630992918 sales@summedchem.com China 1000 58
Huainan Kedi Chemical Factory 0554-2106669 sales1@kedichem.com China 4914 55
Chengdu HuaXia Chemical Reagent Co. Ltd 400-1166-196 13458535857 cdhxsj@163.com China 13323 58
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
Shanghai Brain Biotechnology Co., Ltd. 13564638271 shhjiang1977@163.com China 2983 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Supplier Advantage
Heterochem 58
Chengdu Ai Keda Chemical Technology Co., Ltd. 55
SynAsst Chemical. 55
Shanghai Raise Chemical Technology Co.,Ltd 55
Hebei Summedchem Co.,Ltd 58
Huainan Kedi Chemical Factory 55
Chengdu HuaXia Chemical Reagent Co. Ltd 58
Cool Pharm, Ltd 58
Shanghai Brain Biotechnology Co., Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60

View Latest Price from 3,5-Dimethoxypyridine-4-carboxaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,5-DIMETHOXYPYRIDINE-4-CARBOXALDEHYDE pictures 2020-01-03 3,5-DIMETHOXYPYRIDINE-4-CARBOXALDEHYDE
204862-70-4
 $1.00 1KG 95-99% 1ton Career Henan Chemical Co

3,5-Dimethoxypyridine-4-carboxaldehyde Spectrum

3,5-DIMETHOXYPYRIDINE-4-CARBOXALDEHYDE(204862-70-4)1HNMR

204862-70-4 (3,5-Dimethoxypyridine-4-carboxaldehyde) Related Search:

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3,5-Dimethoxy-4-pyridinecarboxaldehyde 3,5-Dimethoxyisonicotinaldehyde 2-forMyl-3,5-diMethoxypyridine-4-carboxylic acid 4-Pyridinecarboxaldehyde, 3,5-dimethoxy- 3,5-dimethoxypyridine-4-carbaldehyde 3,5-dimethoxypyridine-4-methylaldehyde 3,5-Dimethoxypyridine-4-carboxaldehyde 204862-70-4 Pyridines