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2-Morpholinobenzaldehyde

CAS No.
58028-76-5
Chemical Name:
2-Morpholinobenzaldehyde
Synonyms
2-Morpholinobenzaldehyde;2-(4-MORPHOLINO)BENZALDEHYDE;4-(2-Formylphenyl)morpholine;2-MORPHOLIN-4-YL-BENZALDEHYDE;2-(4-Morpholinyl)-benzaldehyde;2-MORPHOLINOBENZENECARBALDEHYDE;2-(morpholine-1-yl)benzaldehyde;Benzaldehyde, 2-(4-morpholinyl)-;2- Morpholino-4-yl-benzaldehyde;2-(4-Morpholino)benzaldehyde 97%
CBNumber:
CB7693157
Molecular Formula:
C11H13NO2
Molecular Weight:
191.23
MDL Number:
MFCD00662562
MOL File:
58028-76-5.mol
MSDS File:
SDS
Last updated:2026-09-12 18:55:05

2-Morpholinobenzaldehyde Properties

Melting point 45-48°C
Boiling point 162 °C(Press: 12.0 Torr)
Density 1.163±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form solid
pka 3.88±0.40(Predicted)
color Yellow
InChI InChI=1S/C11H13NO2/c13-9-10-3-1-2-4-11(10)12-5-7-14-8-6-12/h1-4,9H,5-8H2
InChIKey GTTAEWVBVHSDLX-UHFFFAOYSA-N
SMILES C(=O)C1=CC=CC=C1N1CCOCC1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  52
Safety Statements  24/25
HazardClass  IRRITANT
HS Code  2934999090

2-Morpholinobenzaldehyde price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR8138 2-(Morpholin-4-yl)benzaldehyde 97% 58028-76-5 1g $21 2026-06-04 Buy
Activate Scientific AS20321 2-Morpholinobenzaldehyde 98% 58028-76-5 1g $24 2026-06-04 Buy
Activate Scientific AS20321 2-Morpholinobenzaldehyde 98% 58028-76-5 5g $36 2026-06-04 Buy
Activate Scientific AS20321 2-Morpholinobenzaldehyde 98% 58028-76-5 25g $167 2026-06-04 Buy
Activate Scientific AS20321 2-Morpholinobenzaldehyde 98% 58028-76-5 100g $559 2026-06-04 Buy
Product number Packaging Price Buy
OR8138 1g $21 Buy
AS20321 1g $24 Buy
AS20321 5g $36 Buy
AS20321 25g $167 Buy
AS20321 100g $559 Buy

2-Morpholinobenzaldehyde Chemical Properties,Uses,Production

Uses

Benzaldehyde derivative.

Synthesis

Morpholine

110-91-8

2-Fluorobenzaldehyde

446-52-6

2-MORPHOLINOBENZALDEHYDE

58028-76-5

Example 180: Synthesis of N-(1-methyl-1H-pyrazol-4-yl)-1-(2-morpholinobenzyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine Step (i): 2-fluorobenzaldehyde (0.5 mL, 4.8 mmol), morpholine (0.6 mL, 1.5 eq.), and potassium carbonate (1.3 g, 2 eq.) were mixed and heated in a microwave reactor at 125 °C for 2.5 hours. Upon completion of the reaction, the solvent was removed by evaporation. The residue was partitioned between water and dichloromethane (DCM) and the aqueous phase was further extracted with DCM. All organic phases were combined, dried over sodium sulfate and subsequently concentrated under vacuum to give 2-morpholino benzaldehyde (0.57 g, 63% yield).

References

[1] Russian Chemical Bulletin, 2004, vol. 53, # 6, p. 1240 - 1247
[2] Synthesis, 2010, # 24, p. 4287 - 4299
[3] Patent: WO2011/48082, 2011, A1. Location in patent: Page/Page column 160; 161
[4] Medicinal Chemistry Research, 2015, vol. 24, # 9, p. 3516 - 3528
[5] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1975, p. 1679 - 1682

110-91-8
446-52-6
58028-76-5
Synthesis of 2-Morpholinobenzaldehyde from Morpholine and 2-Fluorobenzaldehyde

2-Morpholinobenzaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 98)Suppliers
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J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
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Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shangchem Co., Ltd. +86-21-68182121 China 881 52
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2-Morpholinobenzaldehyde Spectrum

2-(Morpholin-4-yl)benzaldehyde 97% 4-(2-Formylphenyl)morpholine 2-(4-Morpholinyl)-benzaldehyde 2-(Morpholin-4-yl)benzaldehyde97% 2-MORPHOLIN-4-YL-BENZALDEHYDE 2-MORPHOLINOBENZENECARBALDEHYDE 2-(4-MORPHOLINO)BENZALDEHYDE 2-(4-Morpholino)benzaldehyde 97% 2-MORPHOLIN-4-YL-BENZALDEHYDE, 95+% 2- Morpholino-4-yl-benzaldehyde Benzaldehyde, 2-(4-morpholinyl)- 2-(morpholine-1-yl)benzaldehyde 2-Morpholinobenzaldehyde 58028-76-5 Amines and Anilines Carbonyl Compounds Aromatics Heterocycles