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(R)-LIPOIC ACID

(R)-LIPOIC ACID Structure
(R)-LIPOIC ACID structure
CAS No.
1200-22-2
Chemical Name:
(R)-LIPOIC ACID
Synonyms
(R)-LIPOIC ACID;(R)-LIPOIC ACID;R-ALPHA-LIPOIC ACID;Thiogamma;Tiobe;Lipoec;Tiobec;(R)-(+)-α;ipoic acid;(R)-(+)-α-L
CBNumber:
CB7765979
Molecular Formula:
C8H14O2S2
Molecular Weight:
206.33
MDL Number:
MFCD01631142
MOL File:
1200-22-2.mol
MSDS File:
SDS
Last updated:2026-04-14 09:55:04
Product description Number Pack Size Price
(R)-(+)-α-Lipoic acid analytical standard 04471 100mg $223
(R)-(+)-α-Lipoic acid ≥98.0% (HPLC) 07039 10mg $77.6
(R)-alpha-Lipoic Acid >98.0%(HPLC)(T) L0207 5g $126
(R)-alpha-Lipoic Acid >98.0%(HPLC)(T) L0207 25g $228
(R)-α-Lipoic Acid 27299 5g $86
More product size
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(R)-LIPOIC ACID Properties

Melting point 48-52 °C(lit.)
alpha D23 +104° (c = 0.88 in benzene)
Boiling point 185-195 °C(Press: 0.5 Torr)
Density 1.218±0.06 g/cm3(Predicted)
refractive index 114 ° (C=1, EtOH)
Flash point >230 °F
storage temp. -20°C
solubility Acetonitrile (Slightly), Chloroform (Slightly), DMSO
pka 5.4(at 25℃)
form Solid
color Light Yellow to Yellow
optical activity [α]20/D +104°, c = 1 in chloroform
Merck 14,9326
InChI 1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1
InChIKey AGBQKNBQESQNJD-SSDOTTSWSA-N
SMILES OC(=O)CCCC[C@@H]1CCSS1 || OC(=O)CCCC[C@@H]1CCSS1
LogP 2.160 (est)
CAS DataBase Reference 1200-22-2(CAS DataBase Reference)
FDA UNII VLL71EBS9Z
UNSPSC Code 85151701
NACRES NA.32

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P264-P270-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P501
Risk Statements  22-36/38
Safety Statements  20-36-26-35
WGK Germany  3
HS Code  29349990
Storage Class 11 - Combustible Solids
NFPA 704
0
2 0

(R)-LIPOIC ACID price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 04471 (R)-(+)-α-Lipoic acid analytical standard 1200-22-2 100mg $223 2026-03-19 Buy
Sigma-Aldrich 07039 (R)-(+)-α-Lipoic acid ≥98.0% (HPLC) 1200-22-2 10mg $77.6 2025-07-31 Buy
TCI Chemical L0207 (R)-alpha-Lipoic Acid >98.0%(HPLC)(T) 1200-22-2 5g $126 2026-03-19 Buy
TCI Chemical L0207 (R)-alpha-Lipoic Acid >98.0%(HPLC)(T) 1200-22-2 25g $228 2026-03-19 Buy
Cayman Chemical 27299 (R)-α-Lipoic Acid 1200-22-2 5g $86 2024-03-01 Buy
Product number Packaging Price Buy
04471 100mg $223 Buy
07039 10mg $77.6 Buy
L0207 5g $126 Buy
L0207 25g $228 Buy
27299 5g $86 Buy

(R)-LIPOIC ACID Chemical Properties,Uses,Production

Chemical Properties

Yellow Crystalline Solid
(R)-( )-1,2-Dithiolane-3-pentanoic acid

Uses

A fat-metabolism stimulator

Uses

α-Lipoic acid has been used as a reference standard for the analysis of α-lipoic acid in human plasma by high performance liquid chromatography coupled to electron capture detector (HPLC-ECD), in various food matrices and dietary supplements by HPLC combined with coulometric electrode array detector (CEAD) as well as electrospray ionization mass spectrometer (ESI-MS).
It may be used as a reference standard for the determination of α-lipoic acid in human urine by isocratic reversed-phase HPLC and in α-lipoic acid capsules by HPLC with chemiluminescence detection.

Definition

ChEBI: (R)-lipoic acid is the (R)-enantiomer of lipoic acid. A vitamin-like, C8 thia fatty acid with anti-oxidant properties. It has a role as a prosthetic group, a nutraceutical and a cofactor. It is a lipoic acid, a member of dithiolanes, a heterocyclic fatty acid and a thia fatty acid. It is functionally related to an octanoic acid. It is a conjugate acid of a (R)-lipoate. It is an enantiomer of a (S)-lipoic acid.

General Description

α-Lipoic acid is an antioxidant which is generally present in plants, animals and many other microorganisms.

Biochem/physiol Actions

(R)-(+)-α-Lipoic acid was shown to significantly increase pyruvate oxidation while abrogating fatty acid oxidation in rat hepatocytes. These effects make R-(+)-α-Lipoic acid a promising treatment option for the treatment of Type II diabetes. It is a biological antioxidant with prooxidant activities, its therapeutic potential is widely investigated, e.g. in the treatment for Alzheimer′s disease.

(R)-LIPOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

DIHYDROLIPOIC ACID

(R)-LIPOIC ACID Suppliers

Global( 489)Suppliers
Supplier Tel Email Country ProdList Advantage
Biopole Pharmatech Co., Ltd.
+8615151475053 biopole@163.com China 37 58
GIHI CHEMICALS CO.,LIMITED
+86-571-86217390; +8618058761490 info@gihichemicals.com China 49968 58
Shandong Luning Pharmaceutical Co., Ltd.
+8618753388868 sale@lntzkg.com China 7 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8738 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-81139210 +86-18192627656 1059@dideu.com China 3590 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-86-13131129325 +8613131129325 sales1@chuanghaibio.com China 5235 58
Hebei Dangtong Import and export Co LTD 		+86-86-4001020630 +8619831957301 admin@hbdangtong.com China 1000 58
PNP Biotech Co. Ltd 		+8618516098983 sales@pnpbiotech.com China 1001 58
Henan Bao Enluo International TradeCo.，LTD 		+86-17331933971 deasea125996@gmail.com China 2472 58
HR Biotechnology Co.,Ltd 		+8618565342920 sales@chembj.net China 282 58
Supplier Advantage
Biopole Pharmatech Co., Ltd.
58
GIHI CHEMICALS CO.,LIMITED
58
Shandong Luning Pharmaceutical Co., Ltd.
58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Hebei Dangtong Import and export Co LTD 		58
PNP Biotech Co. Ltd 		58
Henan Bao Enluo International TradeCo.，LTD 		58
HR Biotechnology Co.,Ltd 		58

Related articles

Related Qustion

Ask a question
Q:What is the difference between R and D alpha lipoic acid?Alex - Nov 18，2025
A:R and D alpha lipoic acid are two forms of alpha lipoic acid, R alpha lipoic acid is the natural form and the other is synthetic form. (R)-alpha-Lipoic Acid is an organosulfur compound, it can be used as a dietary supplement and as an antioxidant.

View Lastest Price from (R)-LIPOIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-α-Lipoic Acid pictures 2026-04-17 (R)-α-Lipoic Acid
1200-22-2
 US $0.00-0.00 / Kg/Drum 1KG 99%HPLC; USP 500KGS WUHAN FORTUNA CHEMICAL CO., LTD
(R)-(+)-1,2-Dithiolane-3-pentanoic acid pictures 2026-04-17 (R)-(+)-1,2-Dithiolane-3-pentanoic acid
1200-22-2
 0.99 RongNa Biotechnology Co.,Ltd
(R)-(+)-1,2-Dithiolane-3-pentanoic acid pictures 2026-04-17 (R)-(+)-1,2-Dithiolane-3-pentanoic acid
1200-22-2
 US $0.00-0.00 / kg 1kg 99% 20t Jinan Jianfeng Chemical Co., Ltd
  • (R)-α-Lipoic Acid pictures
  • (R)-α-Lipoic Acid
    1200-22-2
  • US $0.00-0.00 / Kg/Drum
  • 99%HPLC; USP
  • WUHAN FORTUNA CHEMICAL CO., LTD

(R)-LIPOIC ACID Spectrum

(R)-(+)-1,2-Dithiolane-3-pentanoic acid(1200-22-2)MS(R)-(+)-1,2-Dithiolane-3-pentanoic acid(1200-22-2)1HNMR(R)-(+)-1,2-Dithiolane-3-pentanoic acid(1200-22-2)1HNMR(R)-(+)-1,2-Dithiolane-3-pentanoic acid(1200-22-2)IR1

1200-22-2((R)-LIPOIC ACID)Related Search:

α-Lipoic Acid R-alpha-Lipoic acid tromethamine salt Lipoic acid tromethamine salt (R)-6,8-Dimercaptooctanoic acid Sodium thioctate
OCTOTIAMINE 1,2,3-Trithiane-4-pentanoic Acid Lipoic Acid Related CoMpound rac α-Lipoic Acid-d5 R-Lipoic Acid Impurity 1 (S-Oxide)
Sodium (R)-alpha-lipoate 1,2-Dithiolane-3-pentanoic acid DL-1,2-DITHIOLANE-3-PENTANOIC ACID REDUCED FORM 1,2-Dithiolane-3-pentanoic acid 1-oxide DL-1,2-DITHIOLANE-3-PENTANOIC ACID
(S)-1,2-Dithiolane-3-pentanoic acid,1,2-Dithiolane-3-pentanoic acid, (S)-,1,2-Dithiolane-3-pentanoic acid, (3S)- (9CI) (+/-)-1,2-Dithiolane-3-pentanoic Acid-d5 (R)-1,2-Dithiolane-3-pentanoic acid polymer with 2-hydroxypropanoic ac id

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5-[(3R)-1,2-dithiolan-3-yl]pentanoic acid 5-[(3R)-dithiolan-3-yl]pentanoic acid 5-[(3R)-dithiolan-3-yl]valeric acid (R)-(+)-1,2-Dithiola (R)-5-(1,2-Dithiolan-3-yl)pentanoic acid (R)-Thioctic Acid (R)-1,2-Dithiolane-3-valeric Acid D-lipoic acid (R)-(+)-1,2-Dithiolane-3-pentanoic acid 97% (R)-LIPOIC ACID Acid (R)-(+)-Lipoic acid,(R)-(+)-Thioctic acid,(R)-(+)- 1,2-Dithiolane-3-pentanoic acid Lipoic acid ((R)-(+)-α-Lipoic acid (R)-alpha-Thioctic Acid Thioctic Acid Impurity 19 (R)-LIPOIC ACID R-(+)-ALPHA-LIPOIC ACID (R)-(+)-1,2-DITHIOLANE-3-PENTANOIC ACID (R)-(+)-Thioctic Acid R-(+)-Alpha-Lipoic Acid 1200-22-2 (3R)-1,2-Dithiolane-3-pentanoic Acid (R)-(+)-a-Lipoic Acid Byodinoral 300 Lipoec Thiogamma Tiobe 1,2-Dithiolane-3-pentanoic acid, (3R)- LIPOIC ACID (D-LIPOIC ACID) R-A-LIPOIC ACID (D-LIPOIC ACID) 1,2-Dithiolane-3-pentanoic acid, (3R)- (9CI) 1,2-Dithiolane-3-pentanoic acid, (R)- Tiobec (R)-1,2-Dithiolane-3-valeric Acid R (+) Alpha lipoic Acid ( D-Form) (R)-α-LipoicAcid> ipoic acid (R)-(+)-α-Lipoic acid (R)-(+)-α-L (R)-lipoicaci DITHIOLANE-3-PENTANOIC ACID Lipoic Acid [R-(+)-Thioctic acid (R)-(+)-α Lipoic acid, 10 mM in DMSO (R)-(+)-α-Lipoic acid (R)-(+)-1,2-Dithiolane-3-pentanoic acid (+)-α-Lipoic acid (R)-LIPOIC ACID D-Lipoic Acid (Isomer < 0.5%) R-ALPHA-LIPOIC ACID 1200-22-2 200-22-2 Asymmetric Synthesis Chiral Building Blocks Heterocyclic Building Blocks Others API Sulfur & Selenium Compounds Chiral Building Blocks Heterocyclic Building Blocks Others