Sodium thioctate
- CAS No.
- 2319-84-8
- Chemical Name:
- Sodium thioctate
- Synonyms
- SODIUM LIPOATE;sodium thioctate;Sodium α-Lipoate;α-Lipoic Acid (sodium);alpha-Lipoic Acid Sodium;Thioctic acid sodium salt;ALPHALIPOICACIDSODIUMSALT;Sodium thioctate SODIUM LIPOATE;Sodium 5-(dithiolan-3-yl)pentanoate;sodium 5-(1,2-dithiolan-3-yl)pentanoate
- CBNumber:
- CB4512242
- Molecular Formula:
- C8H13NaO2S2
- Molecular Weight:
- 228.31
- MDL Number:
- MOL File:
- 2319-84-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| form | solid |
|---|---|
| color | Beige |
| FDA UNII | L9R2WBJ3BR |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P280-P302+P352-P362+P364 |
| HS Code | 2934999090 |
Sodium thioctate price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 289435 | Sodium Thioctate ≥97% | 2319-84-8 | 5g | $283 | 2026-06-03 | Buy |
| Usbiological | 289435 | Sodium Thioctate ≥97% | 2319-84-8 | 25g | $566 | 2026-06-03 | Buy |
| Usbiological | 289435 | Sodium Thioctate ≥97% | 2319-84-8 | 50g | $779 | 2026-06-03 | Buy |
| Usbiological | 289435 | Sodium Thioctate ≥97% | 2319-84-8 | 100g | $1238 | 2026-06-03 | Buy |
| Apolloscientific | OR925086 | Sodium thioctate 98% | 2319-84-8 | 1g | $26 | 2026-06-04 | Buy |
Sodium thioctate Chemical Properties, Uses, Production
Uses
α-Lipoic Acid (Thioctic acid) sodium is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid sodium inhibits NF-κB-dependent HIV-1 LTR activation[1][2][3]. α-Lipoic Acid sodium induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells[4]. α-Lipoic Acid sodium can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1[5].
in vivo
C57BL/6J mice, divided into four groups, are fed an high-fat diet (HFD) for 24 weeks to induce nonalcoholic fatty liver disease (NAFLD) followed by daily administration of α-Lipoic Acid. Then, the effects of α-Lipoic Acid on hepatic lipid accumulation in long-term HFD-fed mice are assessed. Administration of α-Lipoic Acid (100 mg/kg or 200 mg/kg) markedly reduces visceral fat mass in mice. In addition, α-Lipoic Acid (100 mg/kg or 200 mg/kg) treatment inhibits the appetite and causes a dramatic weight loss (all P<0.05)[1].
IC 50
HIV-1; NF-κB; Human Endogenous Metabolite; Microbial Metabolite
References
[1] Xiao L, et al. Activity of the dietary antioxidant ergothioneine in a virus gene-based assay for inhibitors of HIV transcription. Biofactors. 2006;27(1-4):157-65. DOI:10.1002/biof.5520270114
[2] Lei D, et al. Synergistic neuroprotective effect of rasagiline and idebenone against retinal ischemia-reperfusion injury via the Lin28-let-7-Dicer pathway. Oncotarget. 2018 Jan 30;9(15):12137-12153. DOI:10.18632/oncotarget.24343
[3] Yang Y, et al. Alpha-lipoic acid improves high-fat diet-induced hepatic steatosis by modulating the transcription factors SREBP-1, FoxO1 and Nrf2 via the SIRT1/LKB1/AMPK pathway. J Nutr Biochem. 2014 Nov;25(11):1207-1217. DOI:10.1016/j.jnutbio.2014.06.001
[4] Pibiri M, et al. α-Lipoic acid induces Endoplasmic Reticulum stress-mediated apoptosis in hepatoma cells. Sci Rep. 2020 Apr 28;10(1):7139. DOI:10.1038/s41598-020-64004-5
[5] Liu J, et al. Nanoaggregates of Disulfide-Decorated TrxR Inhibitor Promote Cellular Uptake, Selective Targeting, and Antitumor Efficacy. Langmuir, 2022.
Sodium thioctate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan xinyangruihe Chemical Technology Co., Ltd. | 027-18120580375 18120580375 | 669797270@qq.com | China | 5375 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2202 | 55 |
| Beijing Isomersyn Technology CO;LTD | 010-82954736 13391601435 | sales@isomersyn.com | China | 3294 | 57 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Nanjing Sunlida Biological Technology Co., Ltd. | 025-57798810 18652991625 | sales@sunlidabio.com | China | 3223 | 55 |
| Hubei XinyuanShun Chemical Co., Ltd. | 13971561712, 13995564702, 027-50664929 | hbeixys2001@163.com | China | 3110 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15775 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Raw material medicin reagent co.,Ltd | sales@njromanme.com | China | 4511 | 58 |
View Latest Price from Sodium thioctate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | Sodium thioctate
2319-84-8
|
$2.00-5.00 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2026-07-27 | α-Lipoic Acid sodium
2319-84-8
|
10g | TargetMol Chemicals Inc. | ||||
 |
2022-01-27 | Sodium thioctate
2319-84-8
|
1KG | 98.9% | 100 tons | Honest Joy Holdings Limited |
-
- Sodium thioctate
2319-84-8
- $2.00-5.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- α-Lipoic Acid sodium
2319-84-8
- $0.00
- TargetMol Chemicals Inc.
-
- Sodium thioctate
2319-84-8
- $0.00
- 98.9%
- Honest Joy Holdings Limited
