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4-Amino-2-methoxy-benzonitrile

4-Amino-2-methoxy-benzonitrile Structure
4-Amino-2-methoxy-benzonitrile structure
CAS No.
7251-09-4
Chemical Name:
4-Amino-2-methoxy-benzonitrile
Synonyms
NSC 30614;5-Amino-2-cyanoanisole;4-Cyano-3-Methoxyaniline;4-Amino-2-methoxy-benzonitrile;Benzonitrile,4-aMino-2-Methoxy-;4-Amino-2-methoxybenzonitrile >
CBNumber:
CB7797806
Molecular Formula:
C8H8N2O
Molecular Weight:
148.16
MDL Number:
MFCD09027303
MOL File:
7251-09-4.mol
MSDS File:
SDS
Last updated:2026-09-12 18:55:06
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4-Amino-2-methoxy-benzonitrile Properties

Melting point 102℃
Boiling point 351.2±27.0 °C(Predicted)
Density 1.17±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility soluble in Methanol
form powder to crystal
pka 1.30±0.10(Predicted)
color White to Light yellow
InChI InChI=1S/C8H8N2O/c1-11-8-4-7(10)3-2-6(8)5-9/h2-4H,10H2,1H3
InChIKey KTDRJLRJAHBQDQ-UHFFFAOYSA-N
SMILES C(#N)C1=CC=C(N)C=C1OC

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H302+H312+H332-H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
HS Code  2926907090

4-Amino-2-methoxy-benzonitrile price More Price(52)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical A2785 4-Amino-2-methoxybenzonitrile >97.0%(GC)(T) 7251-09-4 1g $155 2026-04-30 Buy
TCI Chemical A2785 4-Amino-2-methoxybenzonitrile >97.0%(GC)(T) 7251-09-4 5g $467 2026-04-30 Buy
Apolloscientific OR926533 4-Amino-2-methoxybenzonitrile >98% 7251-09-4 250mg $21 2026-06-04 Buy
Apolloscientific OR926533 4-Amino-2-methoxybenzonitrile >98% 7251-09-4 1g $30 2026-06-04 Buy
Apolloscientific OR926533 4-Amino-2-methoxybenzonitrile >98% 7251-09-4 5g $86 2026-06-04 Buy
Product number Packaging Price Buy
A2785 1g $155 Buy
A2785 5g $467 Buy
OR926533 250mg $21 Buy
OR926533 1g $30 Buy
OR926533 5g $86 Buy

4-Amino-2-methoxy-benzonitrile Chemical Properties, Uses, Production

Synthesis

2-CYANO-5-NITROANISOLE

101084-96-2

4-AMINO-2-METHOXY-BENZONITRILE

7251-09-4

1. 2-Methoxy-4-nitrobenzonitrile (750 mg, 4.21 mmol) and palladium catalyst (50 mg, 0.47 mmol) were dissolved in methanol (15 mL) at room temperature. 2. The reaction system was subjected to a hydrogen atmosphere (1 atm) with continuous stirring for 48 h. 3. Upon completion of the reaction the palladium catalyst was removed by filtration. 4. The filtrate was concentrated under reduced pressure to give the brownish-red powdery product 4-amino-2-methoxybenzonitrile (679 mg, 4.58 mmol, quantitative yield). 5. The structure of the product was determined by 1H-anionic digestion. 6. The filtrate was concentrated under reduced pressure to give a brown-red powdery product, 4-amino-2-methoxybenzonitrile (679 mg, 4.58 mmol, quantitative yield). 5. The structure of the product was confirmed by 1H-NMR (300 MHz, DMSO-d6): δ 3.32 (3H, s), 6.05-6.29 (4H, m), 7.23 (1H, d, J = 8.3 Hz). ).

References

[1] Patent: EP2759533, 2014, A1. Location in patent: Paragraph 0484; 0485
[2] Synthesis, 2006, # 19, p. 3316 - 3340
[3] Chemistry - A European Journal, 2014, vol. 20, # 31, p. 9504 - 9509
[4] Chemical and Pharmaceutical Bulletin, 2014, vol. 62, # 10, p. 979 - 988
[5] Patent: US2009/42967, 2009, A1. Location in patent: Page/Page column 22

4-Amino-2-methoxy-benzonitrile Preparation Products And Raw materials

Raw materials

2-Cyano-5-nitroanisole Methanol Hydrogen Palladium Activated carbon

Preparation Products

4-Amino-2-methoxy-benzonitrile Suppliers

Global Suppliers ( 96)
Supplier Tel Email Country ProdList Advantage
Henan Alpha Chemical Co., Ltd. 0371-55055611 18137792234 3957071458@qq.com China 9929 58
Shanghai Chemical Pharm-Intermediate Tech.Co., Ltd. 21-54820552 17702105771 188738128@qq.com China 300 66
Shanghai Harvest Chemical Industrial Co., Ltd. 15721252604 17321035817 sales@harvest-chem.com China 2829 64
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Shanghai AmasPharm Co., Ltd. 021-54540637 18621091017 sales@amaspharm.com China 787 62
ZhengZhou HuaWen Chemical Co.Ltd 0370-2785118 17550508557 675141927@qq.com China 3201 55
Shanghai Synthfine Chemical Co.,Ltd 15921303235 sales@synthfine.com China 999 58
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28364 80
TCI Europe 320-37350700 sales@tcieurope.eu Europe 23654 75
Supplier Advantage
Henan Alpha Chemical Co., Ltd. 58
Shanghai Chemical Pharm-Intermediate Tech.Co., Ltd. 66
Shanghai Harvest Chemical Industrial Co., Ltd. 64
Nanjing Chemlin Chemical Co., Ltd 64
Shandong Xiya Chemical Co., Ltd 57
Shanghai AmasPharm Co., Ltd. 62
ZhengZhou HuaWen Chemical Co.Ltd 55
Shanghai Synthfine Chemical Co.,Ltd 58
TOKYO CHEMICAL INDUSTRY CO., LTD. 80
TCI Europe 75

View Latest Price from 4-Amino-2-methoxy-benzonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-AMINO-2-METHOXY-BENZONITRILE pictures 2019-07-06 4-AMINO-2-METHOXY-BENZONITRILE
7251-09-4
 $1.00 1KG 95% 500KG Career Henan Chemical Co

4-Amino-2-methoxy-benzonitrile Spectrum

4-AMINO-2-METHOXY-BENZONITRILE(7251-09-4)1HNMR

7251-09-4 (4-Amino-2-methoxy-benzonitrile) Related Search:

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2,5-dimethoxy-4-nitrobenzonitrile 2,6-dimethoxy-4-nitrobenzonitrile

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4-Cyano-3-Methoxyaniline NSC 30614 Benzonitrile,4-aMino-2-Methoxy- 4-Amino-2-methoxybenzonitrile > 5-Amino-2-cyanoanisole 4-Amino-2-methoxy-benzonitrile 7251-09-4