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BRD5648

BRD5648 Structure
BRD5648 structure
CAS No.
2056261-42-6
Chemical Name:
BRD5648
Synonyms
BRD5648;(R)-BRD0705;BRD5648, 10 mM in DMSO;(4R)-4-Ethyl-7,7-dimethyl-4-phenyl-1,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one;5H-Pyrazolo[3,4-b]quinolin-5-one, 4-ethyl-1,2,4,6,7,8-hexahydro-7,7-dimethyl-4-phenyl-, (4R)-;compound,Glycogen synthase kinase 3,negative,Glycogen synthase kinase-3,BRD-5648,GSK-3,BRD5648,inhibit,BRD 5648,Inhibitor,(R)-enantiomer,control
CBNumber:
CB78024432
Molecular Formula:
C20H23N3O
Molecular Weight:
321.42
MDL Number:
MFCD32690086
MOL File:
2056261-42-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
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BRD5648 Properties

Boiling point 512.0±50.0 °C(Predicted)
Density 1.22±0.1 g/cm3(Predicted)
pka 14.82±0.60(Predicted)
form Solid
color Light yellow to khaki

BRD5648 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth GHD26142 (4R)-4-Ethyl-7,7-dimethyl-4-phenyl-1,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one 2056261-42-6 10mg $1165.6 2026-06-04 Buy
Biosynth GHD26142 (4R)-4-Ethyl-7,7-dimethyl-4-phenyl-1,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one 2056261-42-6 25mg $1900.5 2026-06-04 Buy
Biosynth GHD26142 (4R)-4-Ethyl-7,7-dimethyl-4-phenyl-1,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one 2056261-42-6 50mg $3041 2026-06-04 Buy
ChemScene CS-0114013 BRD5648 99.94% 2056261-42-6 5mg $271 2026-06-04 Buy
ChemScene CS-0114013 BRD5648 99.94% 2056261-42-6 10mg $412 2026-06-04 Buy
Product number Packaging Price Buy
GHD26142 10mg $1165.6 Buy
GHD26142 25mg $1900.5 Buy
GHD26142 50mg $3041 Buy
CS-0114013 5mg $271 Buy
CS-0114013 10mg $412 Buy

BRD5648 Chemical Properties,Uses,Production

Description

BRD5648 is an inactive (R)-enantiomer of BRD0705. BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor. It can be used for acute myeloid leukemia (AML).

Uses

BRD5648 ((R)-BRD0705) is a negative control of BRD0705. BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor with an IC50 of 66 nM and a Kd of 4.8 μM. BRD0705 displays increased selectivity for GSK3α (8-fold) versus GSK3β (IC50 of 515 nM). BRD0705 can be used for acute myeloid leukemia (AML)[1][2].

References

[1] Wagner FF, et al. Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Sci Transl Med. 2018 Mar 7;10(431). pii: eaam8460. DOI:10.1126/scitranslmed.aam8460

BRD5648 Preparation Products And Raw materials

Raw materials

Preparation Products

BRD5648 Suppliers

Global( 20)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Wuhan chuang he chemical co. LTD 15907120073 1261789306@qq.com China 1358 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Nantong Hi-Future Biotechnology Co., Ltd +86-0513; 18051384581 sales@chemhifuture.com China 3075 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Beijing Boorsen Biotechnology Co., Ltd 400-901-9800 18611424007 cis@bioss.com.cn China 9185 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 11975 58
Supplier Advantage
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
BOC Sciences 58
TargetMol Chemicals Inc. 58
Wuhan chuang he chemical co. LTD 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Nantong Hi-Future Biotechnology Co., Ltd 58
TargetMol Chemicals Inc. 58
Beijing Boorsen Biotechnology Co., Ltd 58
Nanjing Shizhou Biology Technology Co.,Ltd 58

View Lastest Price from BRD5648 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BRD5648 pictures 2026-07-27 BRD5648
2056261-42-6
 $38.00-128.00 99.89% 10g TargetMol Chemicals Inc.
BRD5648 pictures 2026-07-27 BRD5648
2056261-42-6
 $38.00-128.00 99.89% 10g TargetMol Chemicals Inc.
  • BRD5648 pictures
  • BRD5648
    2056261-42-6
  • $38.00-128.00
  • 99.89%
  • TargetMol Chemicals Inc.
  • BRD5648 pictures
  • BRD5648
    2056261-42-6
  • $38.00-128.00
  • 99.89%
  • TargetMol Chemicals Inc.

BRD5648 Spectrum

BRD5648(2056261-42-6)1HNMR

2056261-42-6(BRD5648)Related Search:

Anti-Aging Compound Library CHIR-99021 Anti-cancer compound library LY2090314 2-Chloro-N,N-diethyl-5-[[4-[2-[4-[[(MethylaMino)carbonyl]aMino]phenyl]-4-pyridinyl]-2-pyriMidinyl]aMino]benzenesulfonaMide
GF109203X

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BRD5648 (R)-BRD0705 compound,Glycogen synthase kinase 3,negative,Glycogen synthase kinase-3,BRD-5648,GSK-3,BRD5648,inhibit,BRD 5648,Inhibitor,(R)-enantiomer,control 5H-Pyrazolo[3,4-b]quinolin-5-one, 4-ethyl-1,2,4,6,7,8-hexahydro-7,7-dimethyl-4-phenyl-, (4R)- BRD5648, 10 mM in DMSO (4R)-4-Ethyl-7,7-dimethyl-4-phenyl-1,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one 2056261-42-6