GS-9876 monosuccinate
- CAS No.
- 1800046-97-2
- Chemical Name:
- GS-9876 monosuccinate
- Synonyms
- GS-9876 monosuccinate;Lanraplenib monosuccinate
- CBNumber:
- CB78054446
- Molecular Formula:
- C27H31N9O5
- Molecular Weight:
- 561.6
- MDL Number:
- MFCD32690073
- MOL File:
- 1800046-97-2.mol
- MSDS File:
- SDS
GS-9876 monosuccinate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| DC Chemicals | DC28254 | Lanraplenib monosuccinate 98% | 1800046-97-2 | 100mg | $600 | 2026-05-24 | Buy |
| DC Chemicals | DC28254 | Lanraplenib monosuccinate 98% | 1800046-97-2 | 250mg | $1100 | 2026-05-24 | Buy |
| DC Chemicals | DC28254 | Lanraplenib monosuccinate 98% | 1800046-97-2 | 1g | $2200 | 2026-05-24 | Buy |
GS-9876 monosuccinate Chemical Properties, Uses, Production
Uses
Lanraplenib monosuccinate (GS-9876 monosuccinate) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib monosuccinate (GS-9876 monosuccinate) inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans[1][2][3].
References
[1] Di Paolo J, et al. FRI0049 Preclinical Characterization of GS-9876, A Novel, Oral SYK Inhibitor That Shows Efficacy in Multiple Established Rat Models of Collagen-Induced Arthritis.Annals of the Rheumatic Diseases 2016;75:443-444.
[2] Clarke AS, et al. Effects of GS-9876, a novel spleen tyrosine kinase inhibitor, on platelet function and systemic hemostasis. Thromb Res. 2018 Oct;170:109-118. DOI:10.1016/j.thromres.2018.08.012
[3] Kivitz AJ, et al. GS-9876, a Novel, Highly Selective, SYK Inhibitor in Patients with Active Rheumatoid Arthritis: Safety, Tolerability and Efficacy Results of a Phase 2 Study [abstract]. Arthritis Rheumatol.2018; 70 (suppl 10).
GS-9876 monosuccinate Preparation Products And Raw materials
Raw materials
Preparation Products
GS-9876 monosuccinate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4859 | 55 | |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9729 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shanghai Dongyang Biotechnology Co., Ltd. | 0512-13601744364 13601744364 | chemsharker@126.com | China | 1161 | 58 |
| cjbscvictory | 13348960310 13348960310 | 3003867561@qq.com | China | 10233 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| https://hanhongsci.com/ | 021-54306202 18917919676 | info@hanhongsci.com | China | 29982 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
View Latest Price from GS-9876 monosuccinate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | Lanraplenib monosuccinate
1800046-97-2
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2026-07-27 | Lanraplenib monosuccinate
1800046-97-2
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2025-08-22 | Lanraplenib monosuccinate
1800046-97-2
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. |
-
- Lanraplenib monosuccinate
1800046-97-2
- $1520.00-2500.00
- TargetMol Chemicals Inc.
-
- Lanraplenib monosuccinate
1800046-97-2
- $1520.00-2500.00
- TargetMol Chemicals Inc.
-
- Lanraplenib monosuccinate
1800046-97-2
- $1520.00-2500.00
- TargetMol Chemicals Inc.
