Otelixizumab
- CAS No.
- 881191-44-2
- Chemical Name:
- Otelixizumab
- Synonyms
- Otelixizumab;Otelixizumab (anti-CD3);Research Grade Otelixizumab;Research Grade Otelixizumab(DHC27702)
- CBNumber:
- CB78080780
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
| form | Liquid |
|---|---|
| color | Colorless to light yellow |
| FDA UNII | I5HF2X04PB |
Otelixizumab price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0612958 | Otelixizumab 99.64% | 881191-44-2 | 1mg | $282 | 2026-06-04 | Buy |
| ChemScene | CS-0612958 | Otelixizumab 99.64% | 881191-44-2 | 5mg | $737 | 2026-06-04 | Buy |
| ChemScene | CS-0612958 | Otelixizumab 99.64% | 881191-44-2 | 10mg | $1170 | 2026-06-04 | Buy |
| aablocks | AA0294RN | Otelixizumab ≥95%(SDS-PAGE&SEC-HPLC) | 881191-44-2 | 1mg | $480 | 2026-06-02 | Buy |
| aablocks | AA0294RN | Otelixizumab ≥95%(SDS-PAGE&SEC-HPLC) | 881191-44-2 | 5mg | $1600 | 2026-06-02 | Buy |
Otelixizumab Chemical Properties, Uses, Production
Uses
Otelixizumab (ChAglyCD3) is an anti-human CD3 monoclonal antibody and can be used for the research of type 1 diabetes[1].
in vivo
Otelixizumab (ChAglyCD3) (100 μg/mouse; i.v.; once) results in durable disease remission dependent on transferable T cell–mediated tolerance in diabetic transgenic mice[1].
| Animal Model: | BALB/c-huCD3e mice carrying the human CD3e chain[1] |
| Dosage: | 100 μg/mouse |
| Administration: | Intravenous injection, once |
| Result: | Induced secretion of lower amounts of IL-6. Exhibited up-regulation of regulatory T cells. |
References
[1] Kuhn C, et al. Human CD3 transgenic mice: preclinical testing of antibodies promoting immune tolerance. Sci Transl Med. 2011 Feb 2;3(68):68ra10. DOI:10.1126/scitranslmed.3001830
[2] Guglielmi C, et al. Efficacy and safety of otelixizumab use in new-onset type 1 diabetes mellitus. Expert Opin Biol Ther. 2016 Jun;16(6):841-6. DOI:10.1080/14712598.2016.1180363
Otelixizumab Preparation Products And Raw materials
Raw materials
Preparation Products
Otelixizumab Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Guangzhou Hongyuan Chemical Co.,Ltd | 15817493340 | 981810490@qq.com | China | 1577 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10305 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Biolab Reagents | 027-65279366 18108604356 | products@biolabreagent.com | China | 9864 | 58 |
| Wuhan Jingkangen Biomedical Technology Co., Ltd | 13720134139 086-15871494362 13720134139 | orders@jknbiochem.com | China | 7283 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
