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ChemicalBook >> CAS DataBase List >>Benzeneacetamide, N-[2-[(1R)-2-amino-1-methylethyl]-1,2-dihydro-6-methyl-1-oxo-5-isoquinolinyl]-3-fluoro-4-(trifluoromethyl)-

Benzeneacetamide, N-[2-[(1R)-2-amino-1-methylethyl]-1,2-dihydro-6-methyl-1-oxo-5-isoquinolinyl]-3-fluoro-4-(trifluoromethyl)-

Benzeneacetamide, N-[2-[(1R)-2-amino-1-methylethyl]-1,2-dihydro-6-methyl-1-oxo-5-isoquinolinyl]-3-fluoro-4-(trifluoromethyl)- Structure
Benzeneacetamide, N-[2-[(1R)-2-amino-1-methylethyl]-1,2-dihydro-6-methyl-1-oxo-5-isoquinolinyl]-3-fluoro-4-(trifluoromethyl)- structure
CAS No.
1058709-63-9
Chemical Name:
Benzeneacetamide, N-[2-[(1R)-2-amino-1-methylethyl]-1,2-dihydro-6-methyl-1-oxo-5-isoquinolinyl]-3-fluoro-4-(trifluoromethyl)-
Synonyms
P2X7-IN-2;Benzeneacetamide, N-[2-[(1R)-2-amino-1-methylethyl]-1,2-dihydro-6-methyl-1-oxo-5-isoquinolinyl]-3-fluoro-4-(trifluoromethyl)-
CBNumber:
CB78396409
Molecular Formula:
C22H21F4N3O2
Molecular Weight:
435.41
MDL Number:
MOL File:
1058709-63-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
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Benzeneacetamide, N-[2-[(1R)-2-amino-1-methylethyl]-1,2-dihydro-6-methyl-1-oxo-5-isoquinolinyl]-3-fluoro-4-(trifluoromethyl)- Properties

Boiling point 607.4±55.0 °C(Predicted)
Density 1.357±0.06 g/cm3(Predicted)
pka 13.27±0.20(Predicted)

Benzeneacetamide, N-[2-[(1R)-2-amino-1-methylethyl]-1,2-dihydro-6-methyl-1-oxo-5-isoquinolinyl]-3-fluoro-4-(trifluoromethyl)- Chemical Properties, Uses, Production

Uses

P2X7-IN-2 (compound 58) is a P2X7 receptor inhibitor. P2X7-IN-2 inhibits IL-Iβ release with an IC50 value of 0.01 nM. P2X7-IN-2 can be used for the research of autoimmunity, inflammation and cardiovascular disease[1].

References

[1] Kelly, Michael G, et al. Preparation of isoquinolonecarboxamides as P2X7 purinoceptor modulators and uses thereof. WO2008112205 A1. 2008.

Benzeneacetamide, N-[2-[(1R)-2-amino-1-methylethyl]-1,2-dihydro-6-methyl-1-oxo-5-isoquinolinyl]-3-fluoro-4-(trifluoromethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzeneacetamide, N-[2-[(1R)-2-amino-1-methylethyl]-1,2-dihydro-6-methyl-1-oxo-5-isoquinolinyl]-3-fluoro-4-(trifluoromethyl)- Suppliers

Global Suppliers ( 2)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from Benzeneacetamide, N-[2-[(1R)-2-amino-1-methylethyl]-1,2-dihydro-6-methyl-1-oxo-5-isoquinolinyl]-3-fluoro-4-(trifluoromethyl)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
P2X7-IN-2 pictures 2026-07-27 P2X7-IN-2
1058709-63-9
 $1520.00-2500.00 10g TargetMol Chemicals Inc.
  • P2X7-IN-2 pictures
  • P2X7-IN-2
    1058709-63-9
  • $1520.00-2500.00
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1058709-63-9 (Benzeneacetamide, N-[2-[(1R)-2-amino-1-methylethyl]-1,2-dihydro-6-methyl-1-oxo-5-isoquinolinyl]-3-fluoro-4-(trifluoromethyl)-) Related Search:

P2X7-IN-2 TFA P2X7 receptor antagonist-1 Benzeneacetamide, N-[2-[(1R)-2-amino-1-methylethyl]-1,2-dihydro-6-methyl-1-oxo-5-isoquinolinyl]-3-fluoro-4-(trifluoromethyl)- Benzeneacetamide, N-[1,2-dihydro-2-[(1R)-2-hydroxy-1-methylethyl]-6-methyl-1-oxo-5-isoquinolinyl]-3-fluoro-4-(trifluoromethyl)- IL-2 PROTEIN, MOUSE
IL-3 Protein, HUMAN (HIS)

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Benzeneacetamide, N-[2-[(1R)-2-amino-1-methylethyl]-1,2-dihydro-6-methyl-1-oxo-5-isoquinolinyl]-3-fluoro-4-(trifluoromethyl)- P2X7-IN-2 1058709-63-9 C22H21F4N3O2