Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>1,5-Cyclooctadiene

1,5-Cyclooctadiene

1,5-Cyclooctadiene Structure
1,5-Cyclooctadiene structure
CAS No.
111-78-4
Chemical Name:
1,5-Cyclooctadiene
Synonyms
COD;Cycloocta-1,5-diene;1,5-COD;CIS,CIS-1,5-CYCLOOCTADIENE;1,5-CycL;ooctadiene;1,5-CYCLOOCTADIENE;1.5-cyclooctandiene;1,5-Cyclooctanediene;Cyclooctadiene, 1,5-
CBNumber:
CB7852853
Molecular Formula:
C8H12
Molecular Weight:
108.18
MDL Number:
MFCD00001752
MOL File:
111-78-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:41:36
Request For Quotation

1,5-Cyclooctadiene Properties

Melting point -69 °C (lit.)
Boiling point 149-150 °C (lit.)
Density 0.882 g/mL at 25 °C (lit.)
vapor pressure 25.8 mm Hg ( 37.7 °C)
refractive index n20/D 1.493
Flash point 89 °F
storage temp. 2-8°C
solubility soluble in Chloroform
form Liquid
color Clear colorless
Odor Threshold 0.00084ppm
Water Solubility 780 mg/L (20 ºC)
BRN 2036542
Henry's Law Constant 3.8×10-4 mol/(m3Pa) at 25℃, Hilal et al. (2008)
Stability Stable. Flammable.
InChI 1S/C8H12/c1-2-4-6-8-7-5-3-1/h1-2,7-8H,3-6H2/b2-1-,8-7-
InChIKey VYXHVRARDIDEHS-QGTKBVGQSA-N
SMILES C1CC=CCCC=C1
LogP 3.16 at 20℃
CAS DataBase Reference 111-78-4(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 1E1VVD385Z
NIST Chemistry Reference 1,5-Cyclooctadiene(111-78-4)
EPA Substance Registry System 1,5-Cyclooctadiene (111-78-4)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)Health Hazard (GHS08)Environment (GHS09)
GHS02,GHS07,GHS08,GHS09
Signal word  Warning
Hazard statements  H315-H319-H373-H317-H336-H410-H226
Precautionary statements  P501-P273-P272-P240-P260-P210-P233-P243-P241-P242-P271-P264-P280-P370+P378-P391-P314-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P333+P313-P304+P340+P312-P403+P233-P403+P235-P405
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xn,N,Xi
Risk Statements  10-36/38-42/43-65-50/53-22-43-19-20/22-52/53-36/37/38
Safety Statements  26-36-61-60-16-37/39
RIDADR  UN 2520 3/PG 3
WGK Germany  3
RTECS  GX9620000
F  10-23
Autoignition Temperature 431 °F
TSCA  TSCA listed
HazardClass  3.2
PackingGroup  III
HS Code  29021990
Storage Class 3 - Flammable liquids
Hazard Classifications Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
Asp. Tox. 1
Flam. Liq. 3
Hazardous Substances Data 111-78-4(Hazardous Substances Data)
REACH Registrations Active
Limited Quantities 5.0 L (1.3 gallons) (liquid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
3
0

1,5-Cyclooctadiene price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 246050 1,5-Cyclooctadiene purified by redistillation, ≥99% 111-78-4 100ml $68.1 2026-04-30 Buy
Sigma-Aldrich 246050 1,5-Cyclooctadiene purified by redistillation, ≥99% 111-78-4 800ml $367 2026-04-30 Buy
TCI Chemical C0503 1,5-Cyclooctadiene [stabilized with Octadecyl 3-(3',5'-Di-tert-butyl-4'-hydroxyphenyl)propionate] >98.0%(GC) 111-78-4 25mL $23 2026-04-30 Buy
TCI Chemical C0503 1,5-Cyclooctadiene [stabilized with Octadecyl 3-(3',5'-Di-tert-butyl-4'-hydroxyphenyl)propionate] >98.0%(GC) 111-78-4 100mL $35 2026-04-30 Buy
TRC TRC-C984515-50G 1,5-Cyclooctadiene 111-78-4 50g $262 2026-06-03 Buy
Product number Packaging Price Buy
246050 100ml $68.1 Buy
246050 800ml $367 Buy
C0503 25mL $23 Buy
C0503 100mL $35 Buy
TRC-C984515-50G 50g $262 Buy

1,5-Cyclooctadiene Chemical Properties, Uses, Production

Chemical Properties

1,5-Cyclooctadiene is the organic compound with the chemical formula C8H12.It is a colorless liquid with a strong odor. COD has a boiling point of 151°C and a vapor pressure of 6.8mm at 25°C.

Uses

1,5-Cyclooctadiene is generally abbreviated COD, this diene is a useful precursor to other organic compounds and serves as a ligand in organometallic chemistry. 1,5-Cyclooctadiene can be prepared by dimerization of butadiene in the presence of a nickel catalyst, a coproduct being vinylcyclohexene. It is also a chemical intermediate in the production of Nylon.

Chemical Properties

colourless liquid

Uses

Cycloocta-1,5-diene is produced from petroleum distillation fractions and is used as an intermediate in the plastics industry, as a synthetic lubricant, and in numerous other applications.

Synthesis Reference(s)

Tetrahedron Letters, 24, p. 3913, 1983 DOI: 10.1016/S0040-4039(00)94312-0

Synthesis

Fifty mL of THF was added to a 150 mL flask containing (2.53 mmol) saturated methylsilanes.Ni(COD)2 (0.64 mmol) was dissolved in 25 mL of THF in a separate flask. The flasks were cooled to 0C. The flasks were combined through a cannula. The reaction mixture was heated to room temperature. The mixture was stirred for 1 hour. The flask was drained with a pump. The flask was heated to 70C under vacuum to remove the cyclooctadiene and unreacted methicone. Redissolve the residue in toluene. The residue was filtered. Cooling the saturated toluene solution gave the title compound 1,5-cyclooctadiene by evaporation.

Carcinogenicity

None of the components present in this material at concentrations of 0.1% are listed by IARC, NTP, or OSHA as a carcinogen.

Purification Methods

Purify it by GLC. It has been purified via the AgNO3 salt. This is prepared by shaking with a solution of 50% aqueous AgNO3 w/w several times (e.g. 3 x 50mLand4x50mL) at 70ofor ca 20minutes to get a good separation of layers. The upper layers are combined and further extracted with AgNO3 at 40o (2 x 20 mL). The upper layer (19 mL) of original hydrocarbon mixture gives colourless needles of the AgNO3 complex on cooling. The adduct is recrystallised from MeOH (and cooling to 0o). The hydrocarbon is recovered by steam distilling the salt. The distillate is extracted with Et2O, dried (MgSO4), filtered, evaporated and distilled. [Jones J Chem Soc 312 1954,[Beilstein 5 H 116, 5 IV 403.]

1,5-Cyclooctadiene Preparation Products And Raw materials

Raw materials

Preparation Products

(3S,4R)-4-Acetoxy-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]azetidin-2-one Chloro(1,5-cyclooctadiene)iridium(I) dimer Dichloro(cycloocta-1,5-diene)ruthenium(II) Dichloro(1,5-cyclooctadiene)palladium(II) Bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate
Dichloro(1,5-cyclooctadiene)platinum(II) Chloro(1,5-cyclooctadiene)rhodium(I) dimer 9-Oxabicyclo[6.1.0]nonan-4-one(8CI,9CI) 1,3,6-Hexanetricarboxylic acid triethyl ester

1of2

1,5-Cyclooctadiene Suppliers

Global Suppliers ( 199)
Supplier Tel Email Country ProdList Advantage
Nanjing Xinzeyue Chemical Co., Ltd. 025-15298392496 15298392496 1017019739@qq.com China 55 58
Dexin chemical (Shandong) Co. , Ltd. 15853369661 1092794701@qq.com China 159 58
Jiangsu Raien Environmental Protection Technology Co., Ltd 66814573 16651336298 16651336298@163.com China 4965 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Syntechem Co.,Ltd info@syntechem.com China 12973 57
Maya High Purity Chemicals +86 (573) 82222445 (0)18006601000 452520369 sales@maya-r.com China 11693 57
Supplier Advantage
Nanjing Xinzeyue Chemical Co., Ltd. 58
Dexin chemical (Shandong) Co. , Ltd. 58
Jiangsu Raien Environmental Protection Technology Co., Ltd 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Shanghai Hanhong Scientific Co.,Ltd. 64
Shandong Xiya Chemical Co., Ltd 57
Syntechem Co.,Ltd 57
Maya High Purity Chemicals 57

Related articles

  • 1,5-cyclooctadiene-bioactivity
  • 1,5-Cyclooctadiene is the organic compound with the chemical formula C8H12. Generally abbreviated COD, this diene is a useful ....
  • Feb 12,2020

View Latest Price from 1,5-Cyclooctadiene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,5-Cyclooctadiene pictures 2026-09-02 1,5-Cyclooctadiene
111-78-4
 $1.00-100.00 1KG 99% Henan Fengda Chemical Co., Ltd
1,5-Cyclooctadiene pictures 2026-05-15 1,5-Cyclooctadiene
111-78-4
 $1.50 1g 99.0% Min 100 Tons Shaanxi Didu New Materials Co. Ltd
1,5-Cyclooctadiene pictures 2025-06-20 1,5-Cyclooctadiene
111-78-4
 $100.00 1kgkg 0.99 1000 Hebei Yanxi Chemical Co., Ltd.

1,5-Cyclooctadiene Spectrum

1,5-Cyclooctadiene(111-78-4)MS1,5-Cyclooctadiene(111-78-4)1HNMR1,5-Cyclooctadiene(111-78-4)13CNMR1,5-Cyclooctadiene(111-78-4)IR11,5-Cyclooctadiene(111-78-4)Raman

111-78-4 (1,5-Cyclooctadiene) Related Search:

1,7-Octadiene (R)-(+)-2,2',6,6'-Tetramethoxy-4,4'-bis(diphenylphosphino)-3,3'-bipyridine(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate Bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate Copper(I) hexafluoro-2,4-pentanedionate-cyclooctadiene complex 1,5-Cyclooctadiene
Dichloro(cycloocta-1,5-diene)ruthenium(II) dichloro[(1,2,5,6-eta)-1,5-cyclooctadiene]-palladi dichloro[(1,2,5,6-eta)-1,5-cyclooctadiene]-platin Chloro(1,5-cyclooctadiene)rhodium(I) dimer Chloro(1,5-cyclooctadiene)iridium(I) dimer
Ruthenium II cyclooctadiene bis-(2,2,6,6-tetramethylheptanedionate) Bis(1,5-cyclooctadiene)nickel(0) 1,3-Cyclooctadiene 1,3-Cyclooctadiene (+)-1,2-Bis((2S,5S)-2,5-diethylphospholano)benzene(cyclooctadiene)rhodium (I) trifluoromethanesulfonate
(1,5-Cyclooctadiene)dimethylplatinum(II) Acetylacetonato(1,5-cyclooctadiene)rhodium(I) Antioxidant 1076

1of4

COD CIS,CIS-1,5-CYCLOOCTADIENE 1,5-CYCLOOCTADIENE 1,5-CYCLOOCTADIENE, REDISTILLED, 99+% 1,5-Cyclooctadiene, stabilized, 97% CIS,CIS-1,5-CYCLOOCTADIENE , STABILIZED WITH 50-200PPM IRGANOX 1076 1,5-Cyclooctadiene [stabilized with Octadecyl 3-(3',5'-Di-tert-butyl-4'-hydroxyphenyl)propionate] Cyclooctadiene, 1,5- 1,5-Cyclooctanediene cis,cis-1,5-Cyclooctadiene: 99%, stabilized with 50-200ppm Irganox 1076 1,5-Cyclooctadiene,99%,stabilized 1,5-Cyclooctadiene ,98.5% [stabilized] [stabilized with Octadecyl 3-(3 ,5 -Di-tert-butyl-4 -hydroxyphenyl)propionate] 1,5-Cyclooctadiene  1,5-Cyclooctadiene, 99+%, stabilized, purified by redistillation, AcroSeal 1,5-Cyclooctadiene contains 50-150 ppM 4-tert-Butylcatechol, 99% 1,5-Cyclooctadiene purified by redistillation, >=99% 1,5-Cyclooctadiene(COD) 1,5-CYCLOOCTADIENE, 98+%1,5-CYCLOOCTADIENE, 98+%1,5-CYCLOOCTADIENE, 98+%1,5-CYCLOOCTADIENE, 98+% 1,5-Cyclooctadiene[stabilizedwithOctadecyl3-(3',5'-Di-tert-butyl-4'-hydroxyphenyl)propionate]> 1,5-CycL ooctadiene 1,5-Cyclooctadiene ISO 9001：2015 REACH (5Z)-cycloocta-1,5-diene 1.5-cyclooctandiene 1,5-Cyclooctadiene, stabilized with Octadecyl 3-(3',5'-Di-tert-butyl-4'-hydroxyphenyl)propionate，≥ 98.0% 1,5-COD Cycloocta-1,5-diene 1,5-Cyclooctadiene (6CI, 8CI, 9CI, ACI) 111-78-4 Alkenes Building Blocks Cyclic Organic Building Blocks Alkenes Cyclic Organic Building Blocks