ChemicalBook >> CAS DataBase List >>2-(2,6-Dioxopiperidin-3-yl)-5-(prop-2-yn-1-ylamino)isoindoline-1,3-dione

2-(2,6-Dioxopiperidin-3-yl)-5-(prop-2-yn-1-ylamino)isoindoline-1,3-dione

2-(2,6-Dioxopiperidin-3-yl)-5-(prop-2-yn-1-ylamino)isoindoline-1,3-dione structure

CAS No.: 2357110-24-6

Chemical Name:: 2-(2,6-Dioxopiperidin-3-yl)-5-(prop-2-yn-1-ylamino)isoindoline-1,3-dione

Synonyms: Thalidomide-5-NH-C-alkyne;Thalidomide-5-NH-propargyl;2-(2,6-Dioxopiperidin-3-yl)-5-(prop-2-ynylamino)isoindole-1,3-dione;2-(2,6-Dioxopiperidin-3-yl)-5-(prop-2-yn-1-ylamino)isoindoline-1,3-dione;2-(2,6-dioxo-3-piperidinyl)-5-(2-propyn-1-ylamino)-1H-Isoindole-1,3(2H)-dione,;1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-(2-propyn-1-ylamino)-

CBNumber:: CB78713288

Molecular Formula:: C16H13N3O4

Molecular Weight:: 311.29

MDL Number:: MFCD34563706

MOL File:: 2357110-24-6.mol

MSDS File:: SDS

Last updated:2026-05-28 03:04:11

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2-(2,6-Dioxopiperidin-3-yl)-5-(prop-2-yn-1-ylamino)isoindoline-1,3-dione Properties

Boiling point	621.2±55.0 °C(Predicted)
Density	1.496±0.06 g/cm3(Predicted)
form	Solid
pka	10.78±0.40(Predicted)
color	Light yellow to brown

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

2-(2,6-Dioxopiperidin-3-yl)-5-(prop-2-yn-1-ylamino)isoindoline-1,3-dione price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0757824	Thalidomide-5-NH-C-alkyne ≥98%	2357110-24-6	100mg	$41	2026-06-04	Buy
ChemScene	CS-0757824	Thalidomide-5-NH-C-alkyne ≥98%	2357110-24-6	250mg	$76	2026-06-04	Buy
ChemScene	CS-0757824	Thalidomide-5-NH-C-alkyne ≥98%	2357110-24-6	1g	$220	2026-06-04	Buy
ChemScene	CS-0757824	Thalidomide-5-NH-C-alkyne ≥98%	2357110-24-6	5g	$963	2026-06-04	Buy
BroadPharm	bp-40506	Pomalidomide-5'-C1-propargyl	2357110-24-6	250MG	$120	2026-05-24	Buy

Product number	Packaging	Price	Buy
CS-0757824	100mg	$41	Buy
CS-0757824	250mg	$76	Buy
CS-0757824	1g	$220	Buy
CS-0757824	5g	$963	Buy
bp-40506	250MG	$120	Buy

2-(2,6-Dioxopiperidin-3-yl)-5-(prop-2-yn-1-ylamino)isoindoline-1,3-dione Chemical Properties,Uses,Production

Uses

Thalidomide-5-NH-C-alkyne contains an E3 ligase ligand with a terminal alkyne. Thalidomide-5-NH-C-alkyne is ready for conjugation to target proteins for PROTAC.

2-(2,6-Dioxopiperidin-3-yl)-5-(prop-2-yn-1-ylamino)isoindoline-1,3-dione Preparation Products And Raw materials

Raw materials

Preparation Products

2-(2,6-Dioxopiperidin-3-yl)-5-(prop-2-yn-1-ylamino)isoindoline-1,3-dione Suppliers

Global( 18)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Daicel Chiral Technologies (China)CO.,LTD	021-50460086-9 15921403865	han_yajun@dctc.daicel.com	China	7909	65
Shanghai Chaolan Chemical Technology Center	QQ：65489617 13301690235	Sales@ATKchemical.com	China	9699	58
SuZhou Medinoah Co.,LTD.	0512-69561983 13914027025	zhang_q@medinoah.com	China	3925	58
Jilin Province Woda Biotechnology Co., Ltd.	13504435624	1927928688@qq.com	China	1644	58
Zhejiang Huida Biotech Co., LTD	0571-89903022 18679456698	zilong@hizyme.com	China	8001	58
Shanghai Haohong Pharmaceutical Co., Ltd.	400-8210725 4008210725	malulu@leyan.com	China	39796	58
Bide Pharmatech Ltd.	400-1647117 13681763483	product02@bidepharm.com	China	59929	58
Shanghai Yanbang Pharmaceutical Technology Co., Ltd	15618536883	1228181347@qq.com	China	7948	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	9067	58
Abosyn	0512-69561983 13914027025	he_qf@medinoah.com	China	3000	58

Supplier	Advantage
Daicel Chiral Technologies (China)CO.,LTD	65
Shanghai Chaolan Chemical Technology Center	58
SuZhou Medinoah Co.,LTD.	58
Jilin Province Woda Biotechnology Co., Ltd.	58
Zhejiang Huida Biotech Co., LTD	58
Shanghai Haohong Pharmaceutical Co., Ltd.	58
Bide Pharmatech Ltd.	58
Shanghai Yanbang Pharmaceutical Technology Co., Ltd	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Abosyn	58

2357110-24-6(2-(2,6-Dioxopiperidin-3-yl)-5-(prop-2-yn-1-ylamino)isoindoline-1,3-dione)Related Search:

(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)glycine Acetamide, 2-chloro-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]- 3-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)propanoic acid 5-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)-

Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]amino]-

1of2

2-(2,6-Dioxopiperidin-3-yl)-5-(prop-2-yn-1-ylamino)isoindoline-1,3-dione 2-(2,6-dioxo-3-piperidinyl)-5-(2-propyn-1-ylamino)-1H-Isoindole-1,3(2H)-dione, 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-(2-propyn-1-ylamino)- 2-(2,6-Dioxopiperidin-3-yl)-5-(prop-2-ynylamino)isoindole-1,3-dione Thalidomide-5-NH-propargyl Thalidomide-5-NH-C-alkyne 2357110-24-6