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ChemicalBook >> CAS DataBase List >>(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)glycine

(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)glycine

(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)glycine Structure
(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)glycine structure
CAS No.
2412056-27-8
Chemical Name:
(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)glycine
Synonyms
Thalidomide-5-NH-C1-COOH;Thalidomide-5-NH2-CH2-COOH;(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)glycine;2-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-5-isoindolinyl]amino]acetic Acid;N-[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]glycine;inhibit,cancer,Thalidomide,E3 ligase,inflammatory,infectious,Thalidomide-5-NH-2-CH2-COOH,trk,Thalidomide5NH2CH2COOH,Inhibitor,tropomyosin receptor kinase,E3 ligase-recruiting Moiety,neurodegenerative,Thalidomide 5 NH2 CH2 COOH,selective,Ligands for E3 Ligase
CBNumber:
CB89638141
Molecular Formula:
C15H13N3O6
Molecular Weight:
331.28
MDL Number:
MOL File:
2412056-27-8.mol
MSDS File:
SDS
Last updated:2026-06-06 22:25:17
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(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)glycine Properties

solubility DMSO : 33.33 mg/mL (100.61 mM; Need ultrasonic)
form Solid
color Light yellow to green yellow
InChI InChI=1S/C15H13N3O6/c19-11-4-3-10(13(22)17-11)18-14(23)8-2-1-7(16-6-12(20)21)5-9(8)15(18)24/h1-2,5,10,16H,3-4,6H2,(H,20,21)(H,17,19,22)
InChIKey ZATMCTCUKSYXHM-UHFFFAOYSA-N
SMILES O=C1C2=CC(NCC(=O)O)=CC=C2C(=O)N1C1CCC(=O)NC1=O

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)glycine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0371180 Thalidomide-5-NH2-CH2-COOH ≥96% 2412056-27-8 50mg $72 2026-06-04 Buy
ChemScene CS-0371180 Thalidomide-5-NH2-CH2-COOH ≥96% 2412056-27-8 100mg $135 2026-06-04 Buy
ChemScene CS-0371180 Thalidomide-5-NH2-CH2-COOH ≥96% 2412056-27-8 250mg $266 2026-06-04 Buy
ChemScene CS-0371180 Thalidomide-5-NH2-CH2-COOH ≥96% 2412056-27-8 1g $802 2026-06-04 Buy
BroadPharm bp-40573 Pomalidomide-5'-C1-Acid 2412056-27-8 25MG $320 2026-05-24 Buy
Product number Packaging Price Buy
CS-0371180 50mg $72 Buy
CS-0371180 100mg $135 Buy
CS-0371180 250mg $266 Buy
CS-0371180 1g $802 Buy
bp-40573 25MG $320 Buy

(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)glycine Chemical Properties, Uses, Production

Uses

Thalidomide-5-NH2-CH2-COOH (compound 114) is a potent and selective inhibitor of tropomyosin receptor kinase (trk). Thalidomide-5-NH2-CH2-COOH is a ligand of E3 ligase. Thalidomide-5-NH2-CH2-COOH has the potential for researching one or more diseases (extracted from patent WO2021170109A1)[1].

Biological Activity

Thalidomide-5-NH2-CH2-COOH (compound 114) is a potent and selective inhibitor of tropomyosin receptor kinase (trk). Thalidomide-5-NH2-CH2-COOH is a ligand of E3 ligase. Thalidomide-5-NH2-CH2-COOH has the potential for researching one or more diseases (extracted from patent WO2021170109A1)[1].

References

[1]. Jing Liu, et al. Tropomyosin receptor kinase (trk) degradation compounds and methods of use. Patent WO2021170109A1.

(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)glycine Preparation Products And Raw materials

Raw materials

Preparation Products

(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)glycine Suppliers

Global Suppliers ( 31)
Supplier Tel Email Country ProdList Advantage
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7909 65
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9711 58
Jiaxing Deyi Chemical Co., Ltd. 86-0573-85866609 18367600069 945717149@qq.com China 9506 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1644 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 54996 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 043180534350 19917294565 et@chemextension.com China 4445 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
Supplier Advantage
Beijing Ouhe Technology Co., Ltd 60
Daicel Chiral Technologies (China)CO.,LTD 65
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai Chaolan Chemical Technology Center 58
Jiaxing Deyi Chemical Co., Ltd. 58
Jilin Province Woda Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Haohong Pharmaceutical Co., Ltd. 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 58
Bide Pharmatech Ltd. 58

View Latest Price from (2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)glycine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Thalidomide-5-NH2-CH2-COOH pictures 2026-06-06 Thalidomide-5-NH2-CH2-COOH
2412056-27-8
 $59.00-143.00 98.26% 10g TargetMol Chemicals Inc.

(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)glycine Spectrum

(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)glycine(2412056-27-8)1HNMR

2412056-27-8 ((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)glycine) Related Search:

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(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)glycine Thalidomide-5-NH2-CH2-COOH inhibit,cancer,Thalidomide,E3 ligase,inflammatory,infectious,Thalidomide-5-NH-2-CH2-COOH,trk,Thalidomide5NH2CH2COOH,Inhibitor,tropomyosin receptor kinase,E3 ligase-recruiting Moiety,neurodegenerative,Thalidomide 5 NH2 CH2 COOH,selective,Ligands for E3 Ligase Thalidomide-5-NH-C1-COOH N-[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]glycine 2-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-5-isoindolinyl]amino]acetic Acid 2412056-27-8