glisoxepide
- CAS No.
- 25046-79-1
- Chemical Name:
- glisoxepide
- Synonyms
- FBB-4231;RP-22410;Pro-Diaban;BAY B-4231;Glisoxepid;glisoxepide;Glisoxepid (10mM in DMSO);N-[2-[4-(azepan-1-ylcarbamoylsulfamoyl)phenyl]ethyl]-5-methyl-1,2-oxazole-3-carboxamide;3-Isoxazolecarboxamide, N-[2-[4-[[[[(hexahydro-1H-azepin-1-yl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-5-methyl-;Pivaloyloxymethyl [2S-(2?,5?,6?)]-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate monohydrochloride
- CBNumber:
- CB7880449
- Molecular Formula:
- C20H27N5O5S
- Molecular Weight:
- 449.529
- MDL Number:
- MFCD00865498
- MOL File:
- 25046-79-1.mol
- TDS File:
- TDS
| Melting point | 189° |
|---|---|
| Density | 1.2348 (rough estimate) |
| refractive index | 1.6460 (estimate) |
| storage temp. | Refrigerator |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly) |
| form | Solid |
| pka | 5.92±0.10(Predicted) |
| color | Pale Yellow to Yellow |
| FDA UNII | H7SC0I332I |
| NCI Drug Dictionary | glisoxepide |
| ATC code | A10BB11 |
SAFETY
Risk and Safety Statements
| Toxicity | LD50 in mice, rats, cats, dogs (g/kg): >10.0, >10.0, >4.0, >2.0 orally; in mice, rats (mg/kg): 283, 196 i.v. (Tettenborn) |
|---|
glisoxepide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FG61382 | Glisoxepid | 25046-79-1 | 2mg | $150 | 2026-06-04 | Buy |
| Biosynth | FG61382 | Glisoxepid | 25046-79-1 | 1mg | $150 | 2026-06-04 | Buy |
| ChemScene | CS-0017517 | Glisoxepide 95.58% | 25046-79-1 | 5mg | $460 | 2026-06-04 | Buy |
| ChemScene | CS-0017517 | Glisoxepide 95.58% | 25046-79-1 | 10mg | $742 | 2026-06-04 | Buy |
| aablocks | AA00C2VA | Glisoxepid >98% | 25046-79-1 | 5mg | $508 | 2026-05-28 | Buy |
glisoxepide Chemical Properties, Uses, Production
Originator
Pro-Diaban,Bayer,W. Germany,1974
Uses
Labelled Glisoxepid (G410600). Glisoxepid is used as an antidiabetic drug. Glisoxepid is a sulfonylurea derivative used in the treatment of diabetes mellitus type 2.
Definition
ChEBI: Glisoxepide is a sulfonamide.
Manufacturing Process
There is obtained from 4-[β-[5-methyl-isoxazolyl-(3)-carboxamido]-ethyl]-
benzene-sulfonamide (prepared from 5-methyl-isoxazole-(3)-carboxylic acid
chloride and 4-(β-aminoethyl)benzene-sulfonamide hydrochloride, MP 213° to
214°C in pyridine) and chloroformic acid methyl ester, in a yield of 69%, the
compound N-[[-4-[β-[5-methyl-isoxazolyl-(3)-carboxamido]-ethyl]]-benzenesulfonyl]]-methyl-urethane in the form of colorless crystals of MP 173°C.
From the sulfonyl-urethane described above and N-amino-hexamethyleneimine, there is obtained, in a yield of 70%. the compound 4-[[4-[β-[5-methylisoxazolyl-(3)-carboxamido]-ethyl]-benzene-sulfonyl]]-1,1-hexamethylenesemicarbazide in the form of colorless crystals of MP 189°C.
Therapeutic Function
Oral hypoglycemic
glisoxepide Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shaanxi Dideu Newmaterial Co., Ltd. | 029-63373950 17392216152 | 1035@dideu.com | China | 9991 | 58 |
| LGC Science (Shanghai) Ltd. | 17717235263 17717235263 | offer.de@lgcgroup.com | China | 38135 | 58 |
View Latest Price from glisoxepide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Glisoxepide
25046-79-1
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. |
-
- Glisoxepide
25046-79-1
- $1520.00-2500.00
- TargetMol Chemicals Inc.
