1,3-bis(4-amino-2-methyl-6-quinolyl)urea dihydrochloride
- CAS No.
- 5424-37-3
- Chemical Name:
- 1,3-bis(4-amino-2-methyl-6-quinolyl)urea dihydrochloride
- Synonyms
- Surfen;Surfen (NSC-12155);Surfen dihydrochloride;NSC-12155 (surfen hydrate);Aminoquinuride hydrochloride;Aminokinuride dihydrochloride;Aminoquinuride dihydrochloride;Aminoquincarbamide dihydrochloride;1,3-bis(4-amino-2-methyl-6-quinolyl)urea dihydrochloride;1,3-bis(4-amino-2-methylquinolin-6-yl)urea, dihydrochloride
- CBNumber:
- CB7922378
- Molecular Formula:
- C21H22Cl2N6O
- Molecular Weight:
- 445.34498
- MDL Number:
- MFCD01676891
- MOL File:
- 5424-37-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| storage temp. | Store at -20°C |
|---|---|
| solubility | Soluble in DMSO |
| form | Solid |
| color | Off-white to gray |
| FDA UNII | P2YT71SUIU |
1,3-bis(4-amino-2-methyl-6-quinolyl)urea dihydrochloride price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 26670 | Surfen (hydrochloride) ≥98% | 5424-37-3 | 5mg | $109 | 2026-04-30 | Buy |
| Cayman Chemical | 26670 | Surfen (hydrochloride) ≥98% | 5424-37-3 | 10mg | $174 | 2026-04-30 | Buy |
| Cayman Chemical | 26670 | Surfen (hydrochloride) ≥98% | 5424-37-3 | 25mg | $382 | 2026-04-30 | Buy |
| Biosynth | FB139214 | Surfen | 5424-37-3 | 1mg | $196.33 | 2026-06-04 | Buy |
| Biosynth | FB139214 | Surfen | 5424-37-3 | 2mg | $314.12 | 2026-06-04 | Buy |
1,3-bis(4-amino-2-methyl-6-quinolyl)urea dihydrochloride Chemical Properties, Uses, Production
Uses
Surfen dihydrochloride is a potent HS (heparan sulfate) antagonist. Surfen binds to glycosaminoglycans. Surfen neutralizes the anticoagulant activity of both unfractionated and low molecular weight heparins. Surfen affects sulfation of heparin and inhibits degradation by heparin lyases. Surfen inhibits FGF2 binding and signaling. Surfen inhibits cell attachment, and virus infection[1].
IC 50
FGFR2: 5 μM (IC50); HSV-1
storage
Store at -20°C
References
[1] Schuksz M, et al. Surfen, a small molecule antagonist of heparan sulfate. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13075-80. DOI:10.1073/pnas.0805862105
1,3-bis(4-amino-2-methyl-6-quinolyl)urea dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
1,3-bis(4-amino-2-methyl-6-quinolyl)urea dihydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shanghai Rechem science Co., Ltd. | 021-31433387 15618786686 | sales@rechemscience.com | China | 2959 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 021-4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 40000 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3861 | 58 |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 021-61109150 | sales@tcisct.com | China | 29717 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Shaanxi Dideu Newmaterial Co., Ltd. | 029-63373950 17392216152 | 1035@dideu.com | China | 9991 | 58 |
View Latest Price from 1,3-bis(4-amino-2-methyl-6-quinolyl)urea dihydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | Surfen dihydrochloride
5424-37-3
|
$48.00-135.00 | 97.08% | 10g | TargetMol Chemicals Inc. |
-
- Surfen dihydrochloride
5424-37-3
- $48.00-135.00
- 97.08%
- TargetMol Chemicals Inc.
