Ethanone, 1-(1H-pyrazol-3-yl)- (9CI)
- CAS No.
- 20583-33-9
- Chemical Name:
- Ethanone, 1-(1H-pyrazol-3-yl)- (9CI)
- Synonyms
- 3-Acetylpyrazole;1-(3-Pyrazolyl)ethanone;1-(1H-pyrazol-3-yl)- (9CI);Ethanone, 1-(1H-pyrazol-3-yl)-;1-(1H-Pyrazol-3-yl)ethanone HCL;1-(1H-pyridineazole-3-yl)ethylone;Ethanone, 1-(1H-pyrazol-3-yl)- (9CI)
- CBNumber:
- CB81069789
- Molecular Formula:
- C5H6N2O
- Molecular Weight:
- 110.11
- MDL Number:
- MFCD10686790
- MOL File:
- 20583-33-9.mol
- MSDS File:
- SDS
| Melting point | 100-101 °C(Solv: benzene (71-43-2)) |
|---|---|
| Boiling point | 277.7±13.0 °C(Predicted) |
| Density | 1.190±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 10.96±0.10(Predicted) |
| Appearance | Off-white to light yellow Solid |
| InChI | InChI=1S/C5H6N2O/c1-4(8)5-2-3-6-7-5/h2-3H,1H3,(H,6,7) |
| InChIKey | BHTZCIGVYSJBQB-UHFFFAOYSA-N |
| SMILES | C(=O)(C1C=CNN=1)C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933199090 |
Ethanone, 1-(1H-pyrazol-3-yl)- (9CI) price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR941006 | 3-Acetylpyrazole 98% | 20583-33-9 | 100mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR941006 | 3-Acetylpyrazole 98% | 20583-33-9 | 250mg | $24 | 2026-06-04 | Buy |
| Apolloscientific | OR941006 | 3-Acetylpyrazole 98% | 20583-33-9 | 1g | $29 | 2026-06-04 | Buy |
| Apolloscientific | OR941006 | 3-Acetylpyrazole 98% | 20583-33-9 | 5g | $89 | 2026-06-04 | Buy |
| Apolloscientific | OR941006 | 3-Acetylpyrazole 98% | 20583-33-9 | 25g | $437 | 2026-06-04 | Buy |
Ethanone, 1-(1H-pyrazol-3-yl)- (9CI) Chemical Properties, Uses, Production
Uses
Ethanone, 1-(1H-pyrazol-3-yl)- (9CI) can be used in pharmaceutical synthesis.
Synthesis
1423-60-5
18107-18-1
20583-33-9
Example 18, Step A: Trimethylsilylated diazomethane (50 mL, 2 M hexane solution, 300 mmol) was added slowly and dropwise to a solution of but-3-yn-2-one (20.4 g, 300 mmol) in tetrahydrofuran (THF, 250 mL), and the temperature was maintained at 20-30 °C during the reaction using an ice bath (delayed exothermic phenomena were observed). The reaction mixture was stirred continuously for 3 h at room temperature. Upon completion of the reaction, it was quenched by the addition of water (500 mL) and subsequently extracted with ethyl acetate (EtOAc). The organic layers were combined, dried over anhydrous sodium sulfate (Na2SO4), filtered and the filtrate was concentrated under reduced pressure to give the target product 18b (31 g, 94% yield).
References
[1] Patent: WO2012/6760, 2012, A1. Location in patent: Page/Page column 54
Ethanone, 1-(1H-pyrazol-3-yl)- (9CI) Preparation Products And Raw materials
Ethanone, 1-(1H-pyrazol-3-yl)- (9CI) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chongqing Kangheyuecheng Pharmaceutical Technology Co., Ltd. | 023-61183015; 13271886913 | kangheyuecheng@163.com | China | 328 | 55 |
| Jinan Kabotang Biological Technology Co.,Ltd. | 0531-61320525 15866703830 | figo.gao@foxmail.com | China | 7601 | 58 |
| Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd. | 21-57721279 18121011378 | sales@shydchem.com.cn | China | 998 | 56 |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| ZEROSCHEM.CO.,LTD. | 10-61256048 13810278579; | sales@zeroschem.com | China | 1401 | 59 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16306 | 64 |
| skychemical Co.Ltd | 021-20958197 20965099 | sales@skychemical.com | China | 1182 | 57 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9509 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Changsha Luxing Bio-Chem Technology Co., Ltd. | 0731-88827538 15574813303 | luxingbc@126.com | China | 1975 | 65 |
