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2-Pyrazinecarboxamide, 5-[(3R)-3-(3-methyl-2-oxo-1-imidazolidinyl)-1-piperidinyl]-3-[[4-(4-piperidinyl)phenyl]amino]-

2-Pyrazinecarboxamide, 5-[(3R)-3-(3-methyl-2-oxo-1-imidazolidinyl)-1-piperidinyl]-3-[[4-(4-piperidinyl)phenyl]amino]- structure

CAS No.: 1791402-91-9

Chemical Name:: 2-Pyrazinecarboxamide, 5-[(3R)-3-(3-methyl-2-oxo-1-imidazolidinyl)-1-piperidinyl]-3-[[4-(4-piperidinyl)phenyl]amino]-

Synonyms: (R)-5-(3-(3-Methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl)-3-((4-(piperidin-4-yl)phenyl)amino)pyrazine-2-carboxamide;RMA-547;BTK ligand 12;5-[(3R)-3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl]-3-(4-piperidin-4-ylanilino)pyrazine-2-carboxamide;(R)-5-[3-(3-Methyl-2-oxo-1-imidazolidinyl)-1-piperidyl]-3-[[4-(4-piperidyl)phenyl]amino]pyrazine-2-carboxamide;2-Pyrazinecarboxamide, 5-[(3R)-3-(3-methyl-2-oxo-1-imidazolidinyl)-1-piperidinyl]-3-[[4-(4-piperidinyl)phenyl]amino]-;(R)-5-(3-(3-Methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl)-3-((4-(piperidin-4-yl)phenyl)amino)pyrazine-2-carboxamide - [M91169]

CBNumber:: CB812342015

Molecular Formula:: C25H34N8O2

Molecular Weight:: 478.59

MDL Number:

MOL File:: 1791402-91-9.mol

MSDS File:: SDS

Last updated:2025-04-18 09:52:49

Request For Quotation

2-Pyrazinecarboxamide, 5-[(3R)-3-(3-methyl-2-oxo-1-imidazolidinyl)-1-piperidinyl]-3-[[4-(4-piperidinyl)phenyl]amino]- Properties

Boiling point	713.8±60.0 °C(Predicted)
Density	1.289±0.06 g/cm3(Predicted)
pka	14.84±0.50(Predicted)
form	Solid

2-Pyrazinecarboxamide, 5-[(3R)-3-(3-methyl-2-oxo-1-imidazolidinyl)-1-piperidinyl]-3-[[4-(4-piperidinyl)phenyl]amino]- price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0781599	BTK ligand 12 98.23%	1791402-91-9	5mg	$179	2026-06-04	Buy
ChemScene	CS-0781599	BTK ligand 12 98.23%	1791402-91-9	10mg	$282	2026-06-04	Buy
ChemScene	CS-0781599	BTK ligand 12 98.23%	1791402-91-9	25mg	$569	2026-06-04	Buy
ChemScene	CS-0781599	BTK ligand 12 98.23%	1791402-91-9	50mg	$910	2026-06-04	Buy
ChemScene	CS-0781599	BTK ligand 12 98.23%	1791402-91-9	100mg	$1452	2026-06-04	Buy

Product number	Packaging	Price	Buy
CS-0781599	5mg	$179	Buy
CS-0781599	10mg	$282	Buy
CS-0781599	25mg	$569	Buy
CS-0781599	50mg	$910	Buy
CS-0781599	100mg	$1452	Buy

2-Pyrazinecarboxamide, 5-[(3R)-3-(3-methyl-2-oxo-1-imidazolidinyl)-1-piperidinyl]-3-[[4-(4-piperidinyl)phenyl]amino]- Chemical Properties, Uses, Production

Uses

BTK ligand 12 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). BTK ligand 12 can serve as an active control for the target protein ligand of NRX-0492 (HY-153357)[1].

References

[1] Zhang D, et al. NRX-0492 degrades wild-type and C481 mutant BTK and demonstrates in vivo activity in CLL patient-derived xenografts. Blood. 2023 Mar 30;141(13):1584-1596. DOI:10.1182/blood.2022016934

2-Pyrazinecarboxamide, 5-[(3R)-3-(3-methyl-2-oxo-1-imidazolidinyl)-1-piperidinyl]-3-[[4-(4-piperidinyl)phenyl]amino]- Preparation Products And Raw materials

Raw materials

Preparation Products

2-Pyrazinecarboxamide, 5-[(3R)-3-(3-methyl-2-oxo-1-imidazolidinyl)-1-piperidinyl]-3-[[4-(4-piperidinyl)phenyl]amino]- Suppliers

Global Suppliers ( 9)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai XingMo Biotechnology Co., Ltd.	+86 13524779951; 13524779951	2075692521@qq.com	China	294	55
Hunan Huayi Zhide Pharmaceutical Technology Co., Ltd.	17752881701	190060276@qq.com	China	199	58
CAS Aldone(Dalian) Pharmaceutical Science and Technology Co, Ltd.	86-13062552990 13062552990	sales@casaldone.com	China	279	58
Shaoyuan Technology (Shanghai) Co., Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	9831	58
Changsha Fuzhen Biotechnology Co.，LTD	15111215862 18229892877	3062105966@qq.com	China	5569	58
Aikon International Limited	025-58859352 18651614124	2881516338@qq.com	China	9968	58
Hubei Rhema Reference Materials Technology Co., Ltd.	15787879035 15787875101	ydw9035@rmastandards.com	China	9976	58
Dancheng Huatai Biotechnology Co., Ltd.	13482210809 13482210809	hli@3wpharm.com	China	357	58
TargetMol	400-821-0310 15002144251	xuexiang.shao@tsbiochem.com	China	29128	58

Supplier	Advantage
Shanghai XingMo Biotechnology Co., Ltd.	55
Hunan Huayi Zhide Pharmaceutical Technology Co., Ltd.	58
CAS Aldone(Dalian) Pharmaceutical Science and Technology Co, Ltd.	58
Shaoyuan Technology (Shanghai) Co., Ltd.	58
Changsha Fuzhen Biotechnology Co.，LTD	58
Aikon International Limited	58
Hubei Rhema Reference Materials Technology Co., Ltd.	58
Dancheng Huatai Biotechnology Co., Ltd.	58
TargetMol	58

1791402-91-9 (2-Pyrazinecarboxamide, 5-[(3R)-3-(3-methyl-2-oxo-1-imidazolidinyl)-1-piperidinyl]-3-[[4-(4-piperidinyl)phenyl]amino]-) Related Search:

1-Piperidinecarboxylic acid, 4-[4-[[3-(aminocarbonyl)-6-[(3R)-3-(3-methyl-2-oxo-1-imidazolidinyl)-1-piperidinyl]-2-pyrazinyl]amino]phenyl]-, 1,1-dimethylethyl ester 2-Pyrazinecarboxamide, 3-[[4-[1-[[(3S)-1-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]-3-pyrrolidinyl]methyl]-4-piperidinyl]phenyl]amino]-5-[(3R)-3-(3-methyl-2-oxo-1-imidazolidinyl)-1-piperidinyl]- 5-(piperidin-1-yl)-3-((4-(piperidin-4-yl)phenyl)amino)pyrazine-2-carboxamide 2-Pyrazinecarboxamide, 3-[[4-[1-[[1-[6-[[[(3S)-2,6-dioxo-3-piperidinyl]amino]carbonyl]-3-pyridinyl]-4-piperidinyl]methyl]-4-piperidinyl]phenyl]amino]-5-[(3R)-3-(3-methyl-2-oxo-1-imidazolidinyl)-1-piperidinyl]- 2-Pyrazinecarboxamide, 5-[(3R)-3-(3-methyl-2-oxo-1-imidazolidinyl)-1-piperidinyl]-3-[[4-(4-piperidinyl)phenyl]amino]-

2-Pyrazinecarboxamide, 3-[[4-[1-[[1-[6-[[(2,6-dioxo-3-piperidinyl)amino]carbonyl]-3-pyridinyl]-4-piperidinyl]methyl]-4-piperidinyl]phenyl]amino]-5-[(3R)-3-(3-methyl-2-oxo-1-imidazolidinyl)-1-piperidinyl]-

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2-Pyrazinecarboxamide, 5-[(3R)-3-(3-methyl-2-oxo-1-imidazolidinyl)-1-piperidinyl]-3-[[4-(4-piperidinyl)phenyl]amino]- (R)-5-[3-(3-Methyl-2-oxo-1-imidazolidinyl)-1-piperidyl]-3-[[4-(4-piperidyl)phenyl]amino]pyrazine-2-carboxamide BTK ligand 12 (R)-5-(3-(3-Methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl)-3-((4-(piperidin-4-yl)phenyl)amino)pyrazine-2-carboxamide - [M91169] 5-[(3R)-3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl]-3-(4-piperidin-4-ylanilino)pyrazine-2-carboxamide RMA-547 (R)-5-(3-(3-Methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl)-3-((4-(piperidin-4-yl)phenyl)amino)pyrazine-2-carboxamide 1791402-91-9