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1,2,4-Triazine

1,2,4-Triazine structure

CAS No.: 290-38-0

Chemical Name:: 1,2,4-Triazine

Synonyms: as-Triazine;1,2,5-Triazine;1,2,4-Triazine (>90%)

CBNumber:: CB81237850

Molecular Formula:: C3H3N3

Molecular Weight:: 81.08

MDL Number:: MFCD07186237

MOL File:: 290-38-0.mol

Last updated:2025-01-17 10:59:43

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1,2,4-Triazine Properties

Boiling point	197℃
Density	1.173
refractive index	1.5060 (estimate)
Flash point	92℃
storage temp.	2-8°C
solubility	Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly, Heated, Sonicated)
form	Gel
pka	0.98±0.63(Predicted)
color	Very Dark Orange to Very Dark Brown

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

1,2,4-Triazine price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	CHM0376372	1,2,4-TRIAZINE 95.00%	290-38-0	5MG	$502.41	2021-12-16	Buy
J&W Pharmlab	95R0049	[1,2,4]Triazine 96%	290-38-0	500mg	$549	2021-12-16	Buy
Crysdot	CD11152812	1,2,4-Triazine 95+%	290-38-0	1g	$842	2021-12-16	Buy
Crysdot	CD11152812	1,2,4-Triazine 95+%	290-38-0	5g	$2352	2021-12-16	Buy

Product number	Packaging	Price	Buy
CHM0376372	5MG	$502.41	Buy
95R0049	500mg	$549	Buy
CD11152812	1g	$842	Buy
CD11152812	5g	$2352	Buy

1,2,4-Triazine Chemical Properties,Uses,Production

Description

1,2,4-Triazine is an electron-deficient heteroaromatic azadiene capable of participation in inverse electron demand Diels-Alder reactions with electron-rich dienophiles.

Uses

1,2,4-Triazine (>90%) is used in improvements of pesticide formulations with lactamides. 1,2,4-triazines scaffold-valuable lead molecules possess diverse pharmacological activities, easy synthetic routes for synthesis and attracted researchers for development of new chemotherapeutic agents in human and mouse model.

Definition

ChEBI: 1,2,4-triazine is a triazine and a member of 1,2,4-triazines.

Synthesis

1,2,4-Triazine is prepared by a cooled (-75 °C) solution of monomeric Glyoxal (90.0 mmol) in absolute MeOH (200 mL) is added to a solution of formamidrazone hydrochloride (40 mmol) in absolute MeOH (300 mL) at -50 °C. Et3N (200 mmol) is added and the resulting reaction mixture is allowed to stand at 25 °C for 24 h. The MeOH is removed in vacuo at 20 °C and the residue extracted with Et2O (peroxide free, 5×). Vacuum distillation of the residue after evaporation of the Et2O affords 1,2,4-triazine (bp 25-28 °C/0.5 mmHg).

storage

Best stored at 0 °C or below. It is stable to acid, less stable to base, and is hygroscopic; should be stored under anhydrous conditions since it reacts slowly with water and protic solvents.

1,2,4-Triazine Preparation Products And Raw materials

Raw materials

Preparation Products

1,2,4-Triazine Suppliers

Global( 20)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30229	58
HUBEI DING KOSIN TECHNOLOGY	+8613524650931	jason@kosinbio.com	China	953	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42056	58
Guangzhou CATO Research Chemicals Inc.	+86-020-81960175-617 +8615602392859	Intermediate@cato-chem.com	China	3861	58
DAYANG CHEM (HANGZHOU) CO.,LTD	+86-88938639 +86-17705817739	info@dycnchem.com	China	53900	58
Atop-Pharma (Shanghai) Technology Co., Ltd.	+86 (21) 5196-9732		China	996	57
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	025-66028182 18626450290	yftan@aikonchem.com	China	16679	50
Shanghai Rlavie Technology Co., Ltd.	21-67759270 17717059219	sales@rlavie.com	China	1551	55

Supplier	Advantage
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Career Henan Chemica Co	58
HUBEI DING KOSIN TECHNOLOGY	58
Jilin Chinese Academy of Sciences-yanshen Technology	58
Guangzhou CATO Research Chemicals Inc.	58
DAYANG CHEM (HANGZHOU) CO.,LTD	58
Atop-Pharma (Shanghai) Technology Co., Ltd.	57
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	50
Shanghai Rlavie Technology Co., Ltd.	55

1,2,4-Triazine Spectrum

1,2,4-Triazine(290-38-0)¹HNMR

290-38-0(1,2,4-Triazine)Related Search:

2-Methyl-1-butanol 3-HYDROXY-5,6-DIPHENYL-1,2,4-TRIAZINE 3-(4-PHENYL-2-PYRIDYL)-5-PHENYL-1,2,4-TRIAZINE DISULFONIC ACID, DISODIUM SALT 3-(2-PYRIDYL)-5,6-DIPHENYL-1,2,4-TRIAZINE 3-AMINO-1,2,4-TRIAZINE

3-AMINO-7-METHYL-1,2,4-BENZOTRIAZINE-1-OXIDE 3-AMINO-1,2,4-BENZOTRIAZINE-1-N-OXIDE 1,2,4-BENZOTRIAZIN-3-AMINE, 7-CHLORO- 3-AMINO-7-BROMO-1,2,4-BENZOTRIAZINE-1-OXIDE 1,2,4-BENZOTRIAZIN-3-AMINE, 7-METHYL-

5,6-diphenyl-1,2,4-triazine-3-thiol 3-AMINO-7-CHLORO-1,2,4-BENZOTRIAZINE-1-OXIDE 3-AMINO-7-NITRO-1,2,4-BENZOTRIAZINE-1-OXIDE 2,4-BIS[5,6-DI(P-SULFOPHENYL)-1,2,4-TRIAZIN-3-YL]PYRIDINE TETRASODIUM SALT fervenulin

3,5,6-Triphenyl-1,2,4-triazine 5,6-DIPHENYL-1,2,4-TRIAZINE 2,4-BDTP

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as-Triazine 1,2,5-Triazine 1,2,4-Triazine (>90%) 290-38-0