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1,2,4-Triazine

CAS No.
290-38-0
Chemical Name:
1,2,4-Triazine
Synonyms
as-Triazine;1,2,5-Triazine;1,2,4-Triazine (>90%)
CBNumber:
CB81237850
Molecular Formula:
C3H3N3
Molecular Weight:
81.08
MDL Number:
MFCD07186237
MOL File:
290-38-0.mol
Last updated:2026-05-28 02:54:40

1,2,4-Triazine Properties

Boiling point 197℃
Density 1.173
refractive index 1.5060 (estimate)
Flash point 92℃
storage temp. 2-8°C
solubility Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly, Heated, Sonicated)
form Gel
pka 0.98±0.63(Predicted)
color Very Dark Orange to Very Dark Brown

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

1,2,4-Triazine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-T290380-50MG 1,2,4-Triazine (>90%) 290-38-0 50mg $343 2026-06-03 Buy
TRC TRC-T290380-250MG 1,2,4-Triazine (>90%) 290-38-0 250mg $1625 2026-06-03 Buy
TRC TRC-T290380-10MG 1,2,4-Triazine (>90%) 290-38-0 10mg $72 2026-06-03 Buy
aablocks AA002V3E 1,2,4-Triazine 290-38-0 10mg $178 2026-05-28 Buy
aablocks AA002V3E 1,2,4-Triazine 290-38-0 50mg $395 2026-05-28 Buy
Product number Packaging Price Buy
TRC-T290380-50MG 50mg $343 Buy
TRC-T290380-250MG 250mg $1625 Buy
TRC-T290380-10MG 10mg $72 Buy
AA002V3E 10mg $178 Buy
AA002V3E 50mg $395 Buy

1,2,4-Triazine Chemical Properties,Uses,Production

Description

1,2,4-Triazine is an electron-deficient heteroaromatic azadiene capable of participation in inverse electron demand Diels-Alder reactions with electron-rich dienophiles.

Uses

1,2,4-Triazine (>90%) is used in improvements of pesticide formulations with lactamides. 1,2,4-triazines scaffold-valuable lead molecules possess diverse pharmacological activities, easy synthetic routes for synthesis and attracted researchers for development of new chemotherapeutic agents in human and mouse model.

Definition

ChEBI: 1,2,4-triazine is a triazine and a member of 1,2,4-triazines.

Synthesis

1,2,4-Triazine is prepared by a cooled (-75 °C) solution of monomeric Glyoxal (90.0 mmol) in absolute MeOH (200 mL) is added to a solution of formamidrazone hydrochloride (40 mmol) in absolute MeOH (300 mL) at -50 °C. Et3N (200 mmol) is added and the resulting reaction mixture is allowed to stand at 25 °C for 24 h. The MeOH is removed in vacuo at 20 °C and the residue extracted with Et2O (peroxide free, 5×). Vacuum distillation of the residue after evaporation of the Et2O affords 1,2,4-triazine (bp 25-28 °C/0.5 mmHg).

storage

Best stored at 0 °C or below. It is stable to acid, less stable to base, and is hygroscopic; should be stored under anhydrous conditions since it reacts slowly with water and protic solvents.

1,2,4-Triazine Preparation Products And Raw materials

Raw materials

Preparation Products

1,2,4-Triazine Suppliers

Global( 20)Suppliers
Supplier Tel Email Country ProdList Advantage
Atop-Pharma (Shanghai) Technology Co., Ltd. +86 (21) 5196-9732 China 996 57
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66028182 17714375163 yftan@aikonchem.com China 16674 50
Shanghai Rlavie Technology Co., Ltd. 021-67759270 17717059219 sales@rlavie.com China 1850 55
Springchem New Material Technology Co.,Ltd 021-52836897 13917661608 info@spring-chem.com China 2000 58
Career Henan Chemica Co +86-0371-86658258 +86-13203830695 laboratory@coreychem.com China 30203 58
CONIER CHEM AND PHARMA LIMITED sales@conier.com China 49906 58
JW & Y Pharmlab Co., Ltd. 021-64340559 13651849907 xinyu_shi@jwypharmlab.com.cn China 9898 58
Zhengzhou Converging Chemical Co. LTD 0371-53399770 18037166334 3857571523@qq.com China 7099 58
Shanghai Kaisen Biotechnology Co., Ltd 17558870519 sales02@chemsoon.com China 1939 58
Alchem Pharmtech,Inc. 8485655694 sales@alchempharmtech.com United States 63645 58

1,2,4-Triazine Spectrum

as-Triazine 1,2,5-Triazine 1,2,4-Triazine (>90%) 290-38-0