5-Isoxazolecarboxylicacid,3-methyl-,ethylester(6CI,7CI,9CI)
- CAS No.
- 63366-79-0
- Chemical Name:
- 5-Isoxazolecarboxylicacid,3-methyl-,ethylester(6CI,7CI,9CI)
- Synonyms
- ethyl 3-methyl-1,2-oxazole-5-carboxylate;3-methylisoxazole-5-carboxylic acid ethyl ester;3-Methyl-5-Isoxazolecarboxylic acid, ethyl ester;5-Isoxazolecarboxylicacid, 3-methyl-, ethyl ester;5-Isoxazolecarboxylicacid,3-methyl-,ethylester(6CI,7CI,9CI)
- CBNumber:
- CB81287709
- Molecular Formula:
- C7H9NO3
- Molecular Weight:
- 155.15
- MDL Number:
- MFCD11656615
- MOL File:
- 63366-79-0.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H315 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
| HazardClass | IRRITANT |
| HS Code | 2934999090 |
5-Isoxazolecarboxylicacid,3-methyl-,ethylester(6CI,7CI,9CI) price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR346323 | 3-Methyl-isoxazole-5-carboxylic acid ethyl ester 95% | 63366-79-0 | 1g | $153 | 2026-06-04 | Buy |
| Apolloscientific | OR346323 | 3-Methyl-isoxazole-5-carboxylic acid ethyl ester 95% | 63366-79-0 | 5g | $483 | 2026-06-04 | Buy |
| Apolloscientific | OR346323 | 3-Methyl-isoxazole-5-carboxylic acid ethyl ester 95% | 63366-79-0 | 10g | $802 | 2026-06-04 | Buy |
| AK Scientific | W7535 | Ethyl 3-methylisoxazole-5-carboxylate 98%(GC) | 63366-79-0 | 250mg | $26 | 2026-06-04 | Buy |
| AK Scientific | W7535 | Ethyl 3-methylisoxazole-5-carboxylate 98%(GC) | 63366-79-0 | 1g | $76 | 2026-06-04 | Buy |
5-Isoxazolecarboxylicacid,3-methyl-,ethylester(6CI,7CI,9CI) Chemical Properties, Uses, Production
Uses
3-Methyl-5-isoxazole carboxylic acid methyl ester is a carboxylic acid ester compound that can be used as a raw material for organic synthesis.
Synthesis
105-37-3
63366-79-0
A solution of dimethylacetamide (18 mL) of nitroethane (1.7 mL, 24 mmol) was slowly added to a methanolic solution of 0.5 M sodium methanol (48 mL, 24 mmol) under nitrogen protection. After the reaction mixture was cooled to 50 °C, acetyl chloride (1.7 mL, 24 mmol) and ethyl propionate (2.4 mL, 24 mmol) were added sequentially. The reaction mixture was stirred at room temperature for 20 hours. Upon completion of the reaction, the mixture was concentrated under reduced pressure and subsequently partitioned between water and ethyl acetate. The organic layer was separated, washed with saturated brine, dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give an orange oily crude product (3.7 g). The crude product was purified by fast column chromatography (eluent: 10% ethyl acetate/hexane) to afford methyl 3-methyl-5-isoxazolecarboxylate as white crystals (900 mg, 24% yield).
References
[1] Patent: WO2006/91674, 2006, A1. Location in patent: Page/Page column 79
5-Isoxazolecarboxylicacid,3-methyl-,ethylester(6CI,7CI,9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Chembon Pharmaceutical Co., Ltd. | 028-84252981 18583719936 | sales@chembon.com.cn | China | 854 | 64 |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4263 | 65 | |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9509 | 58 |
| Candia Thamtech Company Limited | 0371-86615086 18203638366 0371-86159066 13526786601 | China | 2011 | 60 | |
| HBCChem, Inc. | +1-510-219-6317 | sales@hbcchem.com | United States | 10628 | 60 |
| Shanghai Worldyang Chemical Co.,Ltd. | 021-56795766 | sales@worldyachem.com | China | 9475 | 58 |
View Latest Price from 5-Isoxazolecarboxylicacid,3-methyl-,ethylester(6CI,7CI,9CI) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | 5-Isoxazolecarboxylicacid,3-methyl-,ethylester(6CI,7CI,9CI)
63366-79-0
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2020-01-05 | 5-Isoxazolecarboxylicacid,3-methyl-,ethylester(6CI,7CI,9CI)
63366-79-0
|
$9.80 | 1KG | 97%-99% | 1kg -1000kg | Career Henan Chemical Co |
-
- 5-Isoxazolecarboxylicacid,3-methyl-,ethylester(6CI,7CI,9CI)
63366-79-0
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 5-Isoxazolecarboxylicacid,3-methyl-,ethylester(6CI,7CI,9CI)
63366-79-0
- $9.80
- 97%-99%
- Career Henan Chemical Co
