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2-Pyridinecarboxylicacid,5-nitro-,ethylester(9CI)

2-Pyridinecarboxylicacid,5-nitro-,ethylester(9CI) structure

CAS No.: 30563-98-5

Chemical Name:: 2-Pyridinecarboxylicacid,5-nitro-,ethylester(9CI)

Synonyms: ethyl 5-nitropicolinate;2-Pyridinecarboxylic acid, 5-nitro-, ethyl ester;2-Pyridinecarboxylicacid,5-nitro-,ethylester(9CI)

CBNumber:: CB81296497

Molecular Formula:: C8H8N2O4

Molecular Weight:: 196.16

MDL Number:: MFCD09751108

MOL File:: 30563-98-5.mol

MSDS File:: SDS

Last updated:2026-05-28 03:24:22

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2-Pyridinecarboxylicacid,5-nitro-,ethylester(9CI) Properties

Boiling point	348.3±27.0 °C(Predicted)
Density	1.317±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	-2.21±0.10(Predicted)
Appearance	White to light yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P280-P305+P351+P338

2-Pyridinecarboxylicacid,5-nitro-,ethylester(9CI) price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Matrix Scientific	127062	Ethyl 5-nitropicolinate	30563-98-5	1.00g	$864	2026-05-18	Buy
aablocks	AA00BJHR	Ethyl 5-nitropicolinate 98%	30563-98-5	250mg	$21	2026-05-28	Buy
aablocks	AA00BJHR	Ethyl 5-nitropicolinate 95%	30563-98-5	1g	$57	2026-05-28	Buy
aablocks	AA00BJHR	Ethyl 5-nitropicolinate 98%	30563-98-5	5g	$224	2026-05-28	Buy
aablocks	AA00BJHR	Ethyl 5-nitropicolinate 98%	30563-98-5	10g	$383	2026-05-28	Buy

Product number	Packaging	Price	Buy
127062	1.00g	$864	Buy
AA00BJHR	250mg	$21	Buy
AA00BJHR	1g	$57	Buy
AA00BJHR	5g	$224	Buy
AA00BJHR	10g	$383	Buy

2-Pyridinecarboxylicacid,5-nitro-,ethylester(9CI) Chemical Properties, Uses, Production

Uses

5-Nitro-2-pyridinecarboxylic Acid Ethyl Ester is an intermediate used to prepare 2-(pyridylcarbonyl)cyclohex-1-en-1-ol-3-ones as herbicides.

Synthesis

30651-24-2

64-17-5

2-Pyridinecarboxylicacid,5-nitro-,ethylester(9CI)

30563-98-5

General procedure for the synthesis of ethyl 5-nitropyridinecarboxylate from 5-nitro-2-pyridinecarboxylic acid and ethanol: 5-nitro-2-pyridinecarboxylic acid (38.0 g, 226 mmol) was dissolved in thionyl chloride (50.0 mL, 686 mmol), and heated to reflux for 1 hour. Upon completion of the reaction, the mixture was concentrated to dryness to give a solid. The solid was dissolved in anhydrous ethanol (100 mL) and the reaction was refluxed for 2 hours and then cooled to room temperature. Subsequently, the solvent was removed by evaporation under reduced pressure. The resulting solid residue was dissolved in ethyl acetate (500 mL) and washed sequentially with 1 M aqueous sodium bicarbonate (2 x 300 mL). The organic phase was dried over anhydrous sodium sulfate and concentrated to give 39.0 g (86% yield) of yellow solid product with >95% purity (confirmed by 1H NMR and LC-MS analysis).1H NMR (DMSO-d6) δ: 9.46 (d, 1H, J = 2.1 Hz), 8.76 (dd, 1H, J = 2.1, 8.8 Hz), 8.29 (d, 1H, J = 8.6), 8.29 (d, 1H, J = 8.6). 1H, J = 8.6 Hz), 4.41 (q, 2H, J = 7.1 Hz), 1.36 (t, 3H, J = 7.1 Hz).LC-MS (APCI) m/z: [M + H]+ 197.

References

[1] Journal of Organic Chemistry, 1984, vol. 49, # 20, p. 3681 - 3684
[2] Patent: WO2004/14904, 2004, A1. Location in patent: Page 53-54
[3] Patent: US2005/38078, 2005, A1. Location in patent: Page/Page column 30
[4] Patent: WO2009/141386, 2009, A1. Location in patent: Page/Page column 88-89

2-Pyridinecarboxylicacid,5-nitro-,ethylester(9CI) synthesis

Synthesis of 2-Pyridinecarboxylicacid,5-nitro-,ethylester(9CI) from 5-Nitropyridine-2-carboxylic acid and Ethanol

2-Pyridinecarboxylicacid,5-nitro-,ethylester(9CI) Preparation Products And Raw materials

Raw materials

5-Nitropyridine-2-carboxylic acid Ethanol

Preparation Products

2-Pyridinecarboxylicacid,5-nitro-,ethylester(9CI) Suppliers

Global Suppliers ( 36)

Supplier	Tel	Email	Country	ProdList	Advantage
PharmaBlock Sciences (Nanjing),Inc.	025-86918202 4000255188	sales@pharmablock.com	China	5000	55
Chiba Pharmaceutical Science and technology Co, Ltd.	0531-81313138 13066006660	chibapharm@foxmail.com	China	3996	55
Hangzhou Sage Chemical Co., Ltd.	+86057186818502 13588463833	info@sagechem.com	China	10265	58
Cool Pharm, Ltd	021-60455363 18019463053	sales@coolpharm.com	China	8455	58
Jiaxing Rich Biological Technology Co., Ltd.	0573-11111111-1111 18969316891	richmol@163.com	China	446	50
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Cochemical Ltd.	029-86115547 17791676824	sales@cochemical.com	China	6736	58
Aikon International Limited	025-58859352 13913916777	dt3@aikonchem.com	China	15490	58
Shanghai Sealing Biotechnology Co. Ltd..	15721176654;15710104046	1815535157@qq.com	China	984	58
ANHUI WITOP BIOTECH CO., LTD	+8618071025641	eric@witopchemical.com	China	23504	58

Supplier	Advantage
PharmaBlock Sciences (Nanjing),Inc.	55
Chiba Pharmaceutical Science and technology Co, Ltd.	55
Hangzhou Sage Chemical Co., Ltd.	58
Cool Pharm, Ltd	58
Jiaxing Rich Biological Technology Co., Ltd.	50
Amadis Chemical Company Limited	58
Cochemical Ltd.	58
Aikon International Limited	58
Shanghai Sealing Biotechnology Co. Ltd..	58
ANHUI WITOP BIOTECH CO., LTD	58

2-Pyridinecarboxylicacid,5-nitro-,ethylester(9CI) Spectrum

2-Pyridinecarboxylicacid,5-nitro-,ethylester(9CI)(30563-98-5)¹HNMR

30563-98-5 (2-Pyridinecarboxylicacid,5-nitro-,ethylester(9CI)) Related Search:

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Methyl 5-nitro-2-pyridinecarboxylate 5-Aminopyridine-2-carboxylic Acid 2-Pyridinecarboxylicacid,5-nitro-,ethylester(9CI)

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2-Pyridinecarboxylicacid,5-nitro-,ethylester(9CI) 2-Pyridinecarboxylic acid, 5-nitro-, ethyl ester ethyl 5-nitropicolinate 30563-98-5 PYRIDINE