olivetolic acid
- CAS No.
- 491-72-5
- Chemical Name:
- olivetolic acid
- Synonyms
- Olivetolcarboxylic acid;2,4-Dihydroxy-6-pentylbenzoic acid;139400;olivetolic acid;olivetolic acid 97%;olivanic acid powder 98%;Olivetolic acid in Methanol;Benzoic acid, 2,4-dihydroxy-6-pentyl-;Olivetolic acid 100 μg/mL in Methanol;Olivetolic acid 1000 μg/mL in Methanol
- CBNumber:
- CB81340565
- Molecular Formula:
- C12H16O4
- Molecular Weight:
- 224.25
- MDL Number:
- MFCD28383644
- MOL File:
- 491-72-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 143 °C |
|---|---|
| Boiling point | 403.9±25.0 °C(Predicted) |
| Density | 1.237±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 3.41±0.34(Predicted) |
| form | Solid |
| color | Light Beige to Light Brown |
| Stability | Hygroscopic |
| InChI | InChI=1S/C12H16O4/c1-2-3-4-5-8-6-9(13)7-10(14)11(8)12(15)16/h6-7,13-14H,2-5H2,1H3,(H,15,16) |
| InChIKey | SXFKFRRXJUJGSS-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=C(CCCCC)C=C(O)C=C1O |
| FDA UNII | 3Y8J575L93 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H319-H317 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P272-P280-P301+P312-P330-P302+P352-P304+P340-P305+P351+P338-P362+P364-P333+P313-P321-P337+P313-P363-P501 | |||||||||
| NFPA 704 |
|
olivetolic acid price More Price(56)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 26282 | Olivetolic Acid ≥90%(mixtureofisomers) | 491-72-5 | 25mg | $103 | 2026-04-30 | Buy |
| Cayman Chemical | 26282 | Olivetolic Acid ≥90%(mixtureofisomers) | 491-72-5 | 50mg | $195 | 2026-04-30 | Buy |
| Cayman Chemical | 26282 | Olivetolic Acid ≥90%(mixtureofisomers) | 491-72-5 | 100mg | $267 | 2026-04-30 | Buy |
| Cayman Chemical | 26282 | Olivetolic Acid ≥90%(mixtureofisomers) | 491-72-5 | 250mg | $461 | 2026-04-30 | Buy |
| Cayman Chemical | 26282 | Olivetolic Acid ≥90% (mixture of isomers) | 491-72-5 | 50 mg | $177 | 2024-03-01 | Buy |
olivetolic acid Chemical Properties, Uses, Production
Uses
Olivetolic Acid is a precursor in the synthesis of primin and tetrahydrocannabinol.
Definition
ChEBI: A member of the class of benzoic acids that is salicylic acid in which the hydrogens ortho- and para- to the carboxy group are replaced by a pentyl and a hydroxy group, respectively.
Biosynthesis
Olivetolic acid (OLA) biosynthesis involves the condensation of one hexanoyl-CoA with three malonyl-CoAs by a type III PKS (tetraketide synthase) OLA synthase (C. sativa OLS; CsOLS) and an OLA cyclase (CsOAC), both enzymes were derived from the Cannabis species (C. sativa). Studies have achieved trace amount of OLA production in both E. coli and S. cerevisia[1]. Ma et al. find that Pseudomonas sp LvaE encoding a short-chain acyl-CoA synthetase can efficiently convert hexanoic acid to hexanoyl-CoA. The co-expression of the acetyl-CoA carboxylase, the pyruvate dehydrogenase bypass, the NADPH-generating malic enzyme, as well as the activation of peroxisomal β-oxidation pathway and ATP export pathway are effective strategies to redirect carbon flux toward OLA synthesis.
References
[1] Ma, J, Y. Gu, and P. Xu . "Biosynthesis of cannabinoid precursor olivetolic acid by overcoming rate-limiting steps in genetically engineered Yarrowia lipolytica." Cold Spring Harbor Laboratory(2021).
olivetolic acid Preparation Products And Raw materials
Raw materials
Preparation Products
olivetolic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Taizhou Blazer Biomedical Technology Co., Ltd. | 0523-86112008 13915404123 | sales@blazerbio.com | China | 285 | 58 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| Shanghai Arbor Chemical Co., Ltd. | 021-60451683 15021268886 | sales@arborchemical.com | China | 837 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| Chongqing Xingcan Pharmaceutical Technology Co., Ltd. | 13594048950 19923294409 | xingcanyaoye@sina.com | China | 1591 | 58 |
| Hangzhou J&H Chemical Co., Ltd. | 0571-87396432 | sales@jhechem.com | China | 14905 | 59 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66028182 17714375163 | yftan@aikonchem.com | China | 16674 | 50 |
| Alfa Chemistry | 1-516-6625404 | support@alfa-chemistry.com | United States | 9170 | 60 |
View Latest Price from olivetolic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | Olivetolic acid
491-72-5
|
100g | 99% | 25kg | Xi an Biohorlden Industry Trade Co Ltd | ||
 |
2026-08-07 | olivetolic acid
491-72-5
|
$1.00-50.00 | 1KG | 99% | 20000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2026-07-15 | Olivetolic acid
491-72-5
|
$31.00-106.00 | 99.94% | 10g | TargetMol Chemicals Inc. |
-
- Olivetolic acid
491-72-5
- 99%
- Xi an Biohorlden Industry Trade Co Ltd
-
- olivetolic acid
491-72-5
- $1.00-50.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- Olivetolic acid
491-72-5
- $31.00-106.00
- 99.94%
- TargetMol Chemicals Inc.
