olivetolic acid manufacturers
- Olivetolic acid
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2026-08-25
- CAS:491-72-5
- Min. Order: 100g
- Purity: 99%
- Supply Ability: 25kg
- olivetolic acid
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- $1.00
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2026-08-07
- CAS:491-72-5
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 20000KG
- Olivetolic acid
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- $31.00
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2026-07-15
- CAS:491-72-5
- Purity: 99.94%
- Supply Ability: 10g
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| | olivetolic acid Basic information |
| Product Name: | olivetolic acid | | Synonyms: | olivetolic acid;139400;olivanic acid powder 98%;Benzoic acid, 2,4-dihydroxy-6-pentyl-;Olivetolic acid 1000 μg/mL in Methanol;Olivetolic acid in Methanol;olivetolic acid 97%;Olivetolic acid 100 μg/mL in Methanol | | CAS: | 491-72-5 | | MF: | C12H16O4 | | MW: | 224.25 | | EINECS: | | | Product Categories: | | | Mol File: | 491-72-5.mol |  |
| | olivetolic acid Chemical Properties |
| Melting point | 143 °C | | Boiling point | 403.9±25.0 °C(Predicted) | | density | 1.237±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 3.41±0.34(Predicted) | | form | Solid | | color | Light Beige to Light Brown | | Stability: | Hygroscopic | | InChI | InChI=1S/C12H16O4/c1-2-3-4-5-8-6-9(13)7-10(14)11(8)12(15)16/h6-7,13-14H,2-5H2,1H3,(H,15,16) | | InChIKey | SXFKFRRXJUJGSS-UHFFFAOYSA-N | | SMILES | C(O)(=O)C1=C(CCCCC)C=C(O)C=C1O |
| | olivetolic acid Usage And Synthesis |
| Uses | Olivetolic Acid is a precursor in the synthesis of primin and tetrahydrocannabinol. | | Definition | ChEBI: A member of the class of benzoic acids that is salicylic acid in which the hydrogens ortho- and para- to the carboxy group are replaced by a pentyl and a hydroxy group, respectively. | | Biosynthesis | Olivetolic acid (OLA) biosynthesis involves the condensation of one hexanoyl-CoA with three malonyl-CoAs by a type III PKS (tetraketide synthase) OLA synthase (C. sativa OLS; CsOLS) and an OLA cyclase (CsOAC), both enzymes were derived from the Cannabis species (C. sativa). Studies have achieved trace amount of OLA production in both E. coli and S. cerevisia[1]. Ma et al. find that Pseudomonas sp LvaE encoding a short-chain acyl-CoA synthetase can efficiently convert hexanoic acid to hexanoyl-CoA. The co-expression of the acetyl-CoA carboxylase, the pyruvate dehydrogenase bypass, the NADPH-generating malic enzyme, as well as the activation of peroxisomal β-oxidation pathway and ATP export pathway are effective strategies to redirect carbon flux toward OLA synthesis. | | References | [1] Ma, J, Y. Gu, and P. Xu . "Biosynthesis of cannabinoid precursor olivetolic acid by overcoming rate-limiting steps in genetically engineered Yarrowia lipolytica." Cold Spring Harbor Laboratory(2021). |
| | olivetolic acid Preparation Products And Raw materials |
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