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niguldipine

CAS No.
102993-22-6
Chemical Name:
niguldipine
Synonyms
Dnig;B 844-39;B8509-035;Niguldipine Free Base;3-Methyl-5-(3-(4,4-diphenyl-1-piperidinyl)propyl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate;5-O-[3-(4,4-diphenylpiperidin-1-yl)propyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-(4,4-diphenyl-1-piperidinyl)propyl methyl ester;3-((4,4-Diphenyl-1-piperidinyl)propyl)-5-methyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate hydrochloride;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[3-(4,4-diphenyl-1-piperidinyl)propyl] 5-methyl ester
CBNumber:
CB81393187
Molecular Formula:
C36H39N3O6
Molecular Weight:
609.719
MDL Number:
MFCD00083188
MOL File:
102993-22-6.mol
MSDS File:
SDS
Last updated:2026-07-14 16:49:18

niguldipine Properties

Boiling point 729.5±60.0 °C(Predicted)
Density 1.205±0.06 g/cm3(Predicted)
pka 8.45±0.10(Predicted)
FDA UNII 6Q39TPF0GL

niguldipine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0015421 NIGULDIPINE 95.00% 102993-22-6 5MG $504.52 2021-12-16 Buy
Product number Packaging Price Buy
API0015421 5MG $504.52 Buy

niguldipine Chemical Properties, Uses, Production

Uses

Niguldipine free base is a calcium channel blocker with activity in regulating cardiovascular function. Niguldipine free base can reduce systolic and diastolic blood pressure, thereby increasing heart rate and cardiac output. Niguldipine free base exhibits dose-dependent and sustained increases in coronary blood flow. Niguldipine free base also increases perfusion in the kidneys and femoral arteries, but the effect is temporary and to a lesser extent. The effect of Niguldipine free base on myocardial metabolism is not significant[1].

Definition

ChEBI: Niguldipine is a diarylmethane.

References

[1] Effects of niguldipine, a new dihydropyridine calcium antagonist, on regional blood flow, cardiac performance and myocardial metabolism in anaesthetized open-chest dogs PMID:2757470

niguldipine Preparation Products And Raw materials

Raw materials

Preparation Products

niguldipine Suppliers

Global Suppliers ( 4)
Supplier Tel Email Country ProdList Advantage
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 5985 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29873 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58

View Latest Price from niguldipine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Niguldipine Free Base pictures 2026-08-15 Niguldipine Free Base
102993-22-6
$1520.00-2500.00 98.97% 10g TargetMol Chemicals Inc.
3-((4,4-Diphenyl-1-piperidinyl)propyl)-5-methyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate hydrochloride 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-(4,4-diphenyl-1-piperidinyl)propyl methyl ester 3-Methyl-5-(3-(4,4-diphenyl-1-piperidinyl)propyl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate B 844-39 B8509-035 Dnig 5-O-[3-(4,4-diphenylpiperidin-1-yl)propyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[3-(4,4-diphenyl-1-piperidinyl)propyl] 5-methyl ester Niguldipine Free Base 102993-22-6