niguldipine
- CAS No.
- 102993-22-6
- Chemical Name:
- niguldipine
- Synonyms
- Dnig;B 844-39;B8509-035;Niguldipine Free Base;3-Methyl-5-(3-(4,4-diphenyl-1-piperidinyl)propyl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate;5-O-[3-(4,4-diphenylpiperidin-1-yl)propyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-(4,4-diphenyl-1-piperidinyl)propyl methyl ester;3-((4,4-Diphenyl-1-piperidinyl)propyl)-5-methyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate hydrochloride;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[3-(4,4-diphenyl-1-piperidinyl)propyl] 5-methyl ester
- CBNumber:
- CB81393187
- Molecular Formula:
- C36H39N3O6
- Molecular Weight:
- 609.719
- MDL Number:
- MFCD00083188
- MOL File:
- 102993-22-6.mol
- MSDS File:
- SDS
| Boiling point | 729.5±60.0 °C(Predicted) |
|---|---|
| Density | 1.205±0.06 g/cm3(Predicted) |
| pka | 8.45±0.10(Predicted) |
| FDA UNII | 6Q39TPF0GL |
niguldipine Chemical Properties, Uses, Production
Uses
Niguldipine free base is a calcium channel blocker with activity in regulating cardiovascular function. Niguldipine free base can reduce systolic and diastolic blood pressure, thereby increasing heart rate and cardiac output. Niguldipine free base exhibits dose-dependent and sustained increases in coronary blood flow. Niguldipine free base also increases perfusion in the kidneys and femoral arteries, but the effect is temporary and to a lesser extent. The effect of Niguldipine free base on myocardial metabolism is not significant[1].
Definition
ChEBI: Niguldipine is a diarylmethane.
References
[1] Effects of niguldipine, a new dihydropyridine calcium antagonist, on regional blood flow, cardiac performance and myocardial metabolism in anaesthetized open-chest dogs PMID:2757470
niguldipine Preparation Products And Raw materials
Raw materials
Preparation Products
niguldipine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5985 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29873 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| Supplier | Advantage |
|---|---|
| Nantong QuanYi Biotechnology Co., Ltd | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
View Latest Price from niguldipine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-08-15 | Niguldipine Free Base
102993-22-6
|
$1520.00-2500.00 | 98.97% | 10g | TargetMol Chemicals Inc. |
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- Niguldipine Free Base
102993-22-6
- $1520.00-2500.00
- 98.97%
- TargetMol Chemicals Inc.




