Fukinolide
- CAS No.
- 18455-98-6
- Chemical Name:
- Fukinolide
- Synonyms
- Fukinolide;Bakkenolide B;(-)-Bakkenolide B;Spironolactone EP Impurity 16;(1'R,3R,7'aβ)-1'β-Acetoxy-3'aβ,4'β-dimethyl-4-methylene-7'α-[[(2Z)-2-methyl-2-butenoyl]oxy]spiro[oxolane-3,2'-hydrindane]-2-one;2-Butenoic acid, 2-methyl-, (2'R,3'R,3'aR,4'S,7'S,7'aR)-3'-(acetyloxy)decahydro-7',7'a-dimethyl-4-methylene-2-oxospiro[furan-3(2H),2'-[2H]inden]-4'-yl ester, (2Z)-;(Z)-2-Methyl-2-butenoic acid [(3R,3'aα)-3'α-acetoxy-4,5,1',3',3'a,4',5',6',7',7'a-decahydro-7'α,7'aα-dimethyl-4-methylene-2-oxospiro[furan-3(2H),2'-[2H]inden]-4'β-yl] ester
- CBNumber:
- CB81470538
- Molecular Formula:
- C22H30O6
- Molecular Weight:
- 390.47
- MDL Number:
- MFCD30475697
- MOL File:
- 18455-98-6.mol
Fukinolide Chemical Properties,Uses,Production
Uses
Bakkenolide B is isolated from petasites japonicas leaves and has?anti-allergic and anti-inflammatory effects. Bakkenolide B can be used for the study of asthma[1].
Definition
ChEBI: Bakkenolide B is a terpene lactone.
in vivo
Bakkenolide B (intraperitoneal injection; 1 mg/ml; 1 h before ovalbumin nebulization on days 28, 29, and 30) strongly inhibits the accumulation of eosinophils, macrophages, and lymphocytes to bronchoalveolar lavage fluid (BALF) in ovalbumin-induced asthma mice[1].
| Animal Model: | Ovalbumin-induced asthma mice[1] |
| Dosage: | 1 mg/ml |
| Administration: | Intraperitoneal injection; 1 h before ovalbumin nebulization on days 28, 29, and 30 |
| Result: | Exhibited anti-allergic effects in mice. |
References
[1] Lee KP, et al. Anti-allergic and anti-inflammatory effects of bakkenolide B isolated from Petasites japonicus leaves.J Ethnopharmacol.?2013 Jul 30;148(3):890-4. DOI:10.1016/j.jep.2013.05.037
Fukinolide Preparation Products And Raw materials
Raw materials
Preparation Products
Fukinolide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30230 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38838 | 58 |
| BioBioPha Co., Ltd. | 0871-65217109 13211707573; | y.liu@mail.biobiopha.com | China | 5653 | 65 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3989 | 66 |
| ALB Technology Limited | 702-983-3769 | sales@albtechnology.com | United States | 2993 | 55 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
| Absin Bioscience Inc. | 021-38015121 18438616290 | wulan@absin.cn | China | 24731 | 58 |
