3,5-Dichloro-4-methylaniline
- CAS No.
- 54730-35-7
- Chemical Name:
- 3,5-Dichloro-4-methylaniline
- Synonyms
- SKL201;3,5-Dichloro-4-methylaniline;3,5-Dichloro-4-methylbenzenamine;BenzenaMine, 3,5-dichloro-4-Methyl-
- CBNumber:
- CB81510074
- Molecular Formula:
- C7H7Cl2N
- Molecular Weight:
- 176.04
- MDL Number:
- MFCD00266300
- MOL File:
- 54730-35-7.mol
- MSDS File:
- SDS
| Melting point | 57-59 °C |
|---|---|
| Boiling point | 284.6±35.0 °C(Predicted) |
| Density | 1.334±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform (Slightly), DMSO (Slightly) |
| form | Solid |
| pka | 2.92±0.10(Predicted) |
| color | Beige to Brown |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| HS Code | 2921490090 |
3,5-Dichloro-4-methylaniline price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-D435125-1G | 3,5-Dichloro-4-methylaniline | 54730-35-7 | 1g | $109 | 2026-06-03 | Buy |
| Activate Scientific | AS35151 | 3,5-Dichloro-4-methylaniline 98% | 54730-35-7 | 1g | $36 | 2026-06-04 | Buy |
| Activate Scientific | AS35151 | 3,5-Dichloro-4-methylaniline 98% | 54730-35-7 | 5g | $109 | 2026-06-04 | Buy |
| Activate Scientific | AS35151 | 3,5-Dichloro-4-methylaniline 98% | 54730-35-7 | 25g | $322 | 2026-06-04 | Buy |
| Synthonix | D45791 | 3,5-Dichloro-4-methylaniline 97+% | 54730-35-7 | 250mg | $97 | 2026-05-06 | Buy |
3,5-Dichloro-4-methylaniline Chemical Properties, Uses, Production
Synthesis
7149-69-1
54730-35-7
General procedure for the synthesis of 3,5-dichloro-4-methylaniline from 1,3-dichloro-2-methyl-5-nitrobenzene: First, 1,3-dichloro-2-methyl-5-nitrobenzene (0.50 g, 2.43 mmol) was dissolved in N,N-dimethylformamide (DMF). Subsequently, tin(II) chloride dihydrate (2.74 g, 12.1 mmol) was added all at once. The reaction mixture was stirred at room temperature for 1 hour. After completion of the reaction, the reaction mixture was diluted with ethyl acetate and filtered through a diatomaceous earth pad. The filtrate was sequentially washed four times with water and twice with brine and then dried with anhydrous magnesium sulfate. The dried organic phase was filtered and concentrated to give a dark-colored oil. Finally, the residue was purified by silica gel column chromatography using a gradient elution with 5% to 10% ethyl acetate in hexane solution to give 342 mg (80% yield) of 3,5-dichloro-4-methylaniline as a white flaky solid.
References
[1] Gazzetta Chimica Italiana, 1996, vol. 126, # 3, p. 179 - 185
[2] Tetrahedron, 1998, vol. 54, # 12, p. 2953 - 2966
[3] Patent: WO2007/127763, 2007, A2. Location in patent: Page/Page column 37
[4] Patent: WO2007/127726, 2007, A2. Location in patent: Page/Page column 40
[5] Journal of the Chemical Society, 1931, p. 79,81
3,5-Dichloro-4-methylaniline Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Suzhou Sibian Chemical Technology Co.,Ltd. | 0512-65617459 18915409046 | sales@sibian-chem.com | China | 1917 | 55 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Tianjin Anhao Biological Technology Co., Ltd. | sales@ahpharmatech.com | China | 5734 | 55 |
View Latest Price from 3,5-Dichloro-4-methylaniline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2019-12-20 | 3,5-Dichloro-4-methylaniline
54730-35-7
|
$1.00 | 1KG | 99% | Career Henan Chemical Co |
-

- 3,5-Dichloro-4-methylaniline
54730-35-7
- $1.00
- 99%
- Career Henan Chemical Co
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