Exendin-4 (5-39) amide (trifluoroacetate salt)
- CAS No.
- Chemical Name:
- Exendin-4 (5-39) amide (trifluoroacetate salt)
- Synonyms
- Exendin-4 (5-39) amide (trifluoroacetate salt)
- CBNumber:
- CB815458094
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Exendin-4 (5-39) amide (trifluoroacetate salt) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 35847 | Exendin-4 (5-39) amide (trifluoroacetate salt) ≥95% | 500μg | $168 | 2026-04-30 | Buy | |
| Cayman Chemical | 35847 | Exendin-4 (5-39) amide (trifluoroacetate salt) ≥95% | 1mg | $236 | 2026-04-30 | Buy | |
| Cayman Chemical | 35847 | Exendin-4 (5-39) amide (trifluoroacetate salt) ≥95% | 5mg | $544 | 2026-04-30 | Buy |
Exendin-4 (5-39) amide (trifluoroacetate salt) Chemical Properties, Uses, Production
Description
Exendin-4 (5-39) amide is a 34-amino acid synthetic peptide corresponding to residues 5-39 of exendin-4 (48-86) amide (Item No. 11096) and an antagonist of the glucagon-like peptide 1 (GLP-1) receptor (IC50 = 0.3 nM) that has roles in synaptic transmission.1 It decreases GLP-1-induced increases in intracellular cAMP levels in CHO/pancGLPR cells. Exendin-4 (5-39) amide (10 and 100 nM) increases extracellular glutamate reuptake in primary rat hippocampal astrocytes.2 In vivo, exendin-4 (5-39) amide increases excitatory amino acid transporter 2 (EAAT2) protein levels and decreases the field excitatory postsynaptic potential decay time in the rat dentate gyrus when administered intracerebroventricularly.WARNING This product is not for human or veterinary use.
References
[1] C MONTROSE-RAFIZADEH. High potency antagonists of the pancreatic glucagon-like peptide-1 receptor.[J]. The Journal of Biological Chemistry, 1997, 272 34: 21201-21206. DOI: 10.1074/jbc.272.34.21201
[2] KAZUMA KOBAYASHI. Exendin (5-39), an antagonist of GLP-1 receptor, modulates synaptic transmission via glutamate uptake in the dentate gyrus[J]. Brain Research, 2013, 1505: Pages 1-10. DOI: 10.1016/j.brainres.2013.01.012
Exendin-4 (5-39) amide (trifluoroacetate salt) Preparation Products And Raw materials
Raw materials
Preparation Products
Exendin-4 (5-39) amide (trifluoroacetate salt) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Cayman Chemical Company | -- | sales@caymanchem.com | China | 6808 | 58 |
| Neobioscience Co., Ltd. | -- | info@neobioscience.com | CHINA | 6192 | 58 |
| Supplier | Advantage |
|---|---|
| Cayman Chemical Company | 58 |
| Neobioscience Co., Ltd. | 58 |
