ChemicalBook >> CAS DataBase List >>2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine monohydrochloride
2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine monohydrochloride
- CAS No.
- 945-43-7
- Chemical Name:
- 2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine monohydrochloride
- Synonyms
- DMPH4;6,7-DIMETHYL-5,6,7,8-TETRAHYDRO-PTERINE MONOHYDROC;6,7-DIMETHYL-5,6,7,8-TETRAHYDROPTERIN HYDROCHLORIDE;6,7-dimethyl-5,6,7,8-tetrahydropterin dihydrochloride;6,7-DIMETHYL-5,6,7,8-TETRAHYDROPTERINE MONOHYDROCHLORIDE;2-amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine;2-AMINO-4-HYDROXY-6,7-DIMETHYL-5,6,7,8-TETRAHYDROPTERIDINE;6,7-DiMethyl-5,6,7,8-tetrahydropterine hydrochloride >=95%;2-Amino-4-hydroxy-6,7-dimethyl-5,6,7,8-tetrahydropteridineHCl;2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine, DMPH4
- CBNumber:
- CB8160795
- Molecular Formula:
- C8H14ClN5O
- Molecular Weight:
- 231.68
- MDL Number:
- MFCD00012731
- MOL File:
- 945-43-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-09-12 18:55:23
| Melting point | 244-247 °C (dec.)(lit.) |
|---|---|
| storage temp. | -20°C |
| solubility | PBS (pH 7.2): 1 mg/ml |
| form | White powder. |
| InChI | 1S/C8H13N5O.ClH/c1-3-4(2)11-6-5(10-3)7(14)13-8(9)12-6;/h3-4,10H,1-2H3,(H4,9,11,12,13,14);1H |
| InChIKey | GIHYTRGUZVYCQX-UHFFFAOYSA-N |
| SMILES | Cl[H].CC1Nc2nc(N)nc(O)c2NC1C |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H318-H335 | |||||||||
| Precautionary statements | P280-P302+P352-P305+P351+P338+P310 | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-41-37/38 | |||||||||
| Safety Statements | 26-36-36/37/39-39 | |||||||||
| WGK Germany | - | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine monohydrochloride price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D0387 | 6,7-Dimethyl-5,6,7,8-tetrahydropterine hydrochloride ≥95% | 945-43-7 | 100mg | $141 | 2026-04-30 | Buy |
| Cayman Chemical | 21050 | 6,7-dimethyl-5,6,7,8-Tetrahydropterin (hydrochloride) ≥98% | 945-43-7 | 25mg | $20 | 2026-04-30 | Buy |
| Cayman Chemical | 21050 | 6,7-dimethyl-5,6,7,8-Tetrahydropterin (hydrochloride) ≥98% | 945-43-7 | 50mg | $37 | 2026-04-30 | Buy |
| Cayman Chemical | 21050 | 6,7-dimethyl-5,6,7,8-Tetrahydropterin (hydrochloride) ≥98% | 945-43-7 | 100mg | $69 | 2026-04-30 | Buy |
| Cayman Chemical | 21050 | 6,7-dimethyl-5,6,7,8-Tetrahydropterin (hydrochloride) ≥98% | 945-43-7 | 250mg | $159 | 2026-04-30 | Buy |
2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine monohydrochloride Chemical Properties,Uses,Production
Uses
6, 7-dimethyl-5,6,7, 8-Tetrahydropterin hydrochloride is a synthetic analogue of tetrahydro-L-bioterin and is used as a cofactor required for the NOS isoforms, phenylalanine, tyrosine and tryptophan hydroxylases, and other enzymes[1][2].
Biochem/physiol Actions
Synthetic reduced pterin cofactor for nitric oxide synthetase, and for phenylalanine, tyrosine, and tryptophan hydroxylases; less active than the natural cofactor, tetrahydrobiopterin (BH4).
References
[1] Mayer B, et al. In search of a function for tetrahydrobiopterin in the biosynthesis of nitric oxide. Naunyn Schmiedebergs Arch Pharmacol. 1995 May;351(5):453-63. DOI:10.1007/BF00171035
[2] Suckling CJ, et al. 6-Acetyl-7,7-dimethyl-5,6,7,8-tetrahydropterin is an activator of nitric oxide synthases. Bioorg Med Chem Lett. 2008 Mar 1;18(5):1563-6. DOI:10.1016/j.bmcl.2008.01.079
2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine monohydrochloride Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine monohydrochloride Suppliers
Global( 40)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400-6387771-6039 18920764717 | sales@heowns.com | China | 24636 | 60 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 400-920-5774 | sales@glpbio.cn | China | 6705 | 58 |
| Jiangsu aikang biomedical research and development co., LTD | 025-58859352 17714375163 | qzhang@aikonchem.com | China | 15525 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-17392587031 | 1059@dideu.com | China | 9983 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
945-43-7(2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine monohydrochloride)Related Search:
2-amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine
6,7-DIMETHYL-5,6,7,8-TETRAHYDROPTERINE MONOHYDROCHLORIDE
6,7-DIMETHYL-5,6,7,8-TETRAHYDROPTERIN HYDROCHLORIDE
2-AMINO-6,7-DIMETHYL-4-HYDROXY-5,6,7,8-TETRAHYDROPTERIDINE HYDROCHLORIDE
2-AMINO-4-HYDROXY-6,7-DIMETHYL-5,6,7,8-TETRAHYDROPTERIDINE HYDROCHLORIDE
2-AMINO-4-HYDROXY-6,7-DIMETHYL-5,6,7,8-TETRAHYDROPTERIDINE
2-amino-6,7-dimethyl-5,6,7,8-tetrahydropteridin-4-ol hydrochloride
6,7-DIMETHYL-5,6,7,8-TETRAHYDRO-PTERINE MONOHYDROC
2-Amino-4-hydroxy-6,7-dimethyl-5,6,7,8-tetrahydropteridineHCl
6,7-dimethyl-5,6,7,8-tetrahydropterin dihydrochloride
2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine, DMPH4
2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine, DMPH4, 2-Amino-6,7-dimethyl-5,6,7,8-tetrahydro-4-pteridinol hydrochloride
2-Amino-6,7-dimethyl-5,6,7,8-tetrahydropteridine-4-ol·hydrochloride
2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine hydrochloride,96%
DMPH4
6,7-DiMethyl-5,6,7,8-tetrahydropterine hydrochloride >=95%
2-Amino-6,7-dimethyl-5,6,7,8-tetrahydro-4-pteridinol hydrochloride
2-Amino-6,7-dimethyl-5,6,7,8-tetrahydropteridin-4(1H)-one hydrochloride
2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine monohydrochloride
945-43-7
C8H14ClN5O
C8H13N5O2ClH
C8H13N5OHCl
Building Blocks
Quinazolines
Heterocyclic Building Blocks
Building Blocks
Chemical Synthesis
Heterocyclic Building Blocks
Quinazolines
