Methyl-(3-hydroxypropyl) sulfone
- CAS No.
- 2058-49-3
- Chemical Name:
- Methyl-(3-hydroxypropyl) sulfone
- Synonyms
- 3-(Methylsulfonyl)propan-1-ol;3-(Methylsulfonyl)-1-propanol;Ba 2769;3-methanesulfonylpropan-1-ol;3-hydroxypropylmethylsulfone;3-(methylsulfonyl)-1-propano;3-(Methanesulfonyl)-1-propanol;1-Propanol, 3-(methylsulfonyl)-;Methyl-(3-hydroxypropyl) sulfone;3-(Methylsulfonyl)-1-propanol - [M6981]
- CBNumber:
- CB8182841
- Molecular Formula:
- C4H10O3S
- Molecular Weight:
- 138.19
- MDL Number:
- MFCD01696727
- MOL File:
- 2058-49-3.mol
- MSDS File:
- SDS
| Boiling point | 349.4±25.0 °C(Predicted) |
|---|---|
| Density | 1+-.0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 14.57±0.10(Predicted) |
| form | solid |
| color | White to off-white |
| InChI | InChI=1S/C4H10O3S/c1-8(6,7)4-2-3-5/h5H,2-4H2,1H3 |
| InChIKey | XPXXXQZNUQAFQY-UHFFFAOYSA-N |
| SMILES | C(O)CCS(C)(=O)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H319 |
| Precautionary statements | P301+P310-P305+P351+P338 |
| Hazard Codes | T |
| Risk Statements | 25-36 |
| Safety Statements | 26-45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| PackingGroup | Ⅲ |
| HS Code | 2905599890 |
| Toxicity | mouse,LD50,intravenous,> 5gm/kg (5000mg/kg),Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. Vol. 30, Pg. 242, 1971. |
Methyl-(3-hydroxypropyl) sulfone price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR953133 | 3-(Methylsulfonyl)propan-1-ol 95% | 2058-49-3 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR953133 | 3-(Methylsulfonyl)propan-1-ol 95% | 2058-49-3 | 5g | $56 | 2026-06-04 | Buy |
| Apolloscientific | OR953133 | 3-(Methylsulfonyl)propan-1-ol 95% | 2058-49-3 | 10g | $90 | 2026-06-04 | Buy |
| Matrix Scientific | 034912 | 3-(Methylsulfonyl)-1-propanol | 2058-49-3 | 500.00mg | $16 | 2026-05-18 | Buy |
| Synthonix | M6981 | 3-(Methylsulfonyl)-1-propanol 95% | 2058-49-3 | 1g | $15 | 2026-05-06 | Buy |
Methyl-(3-hydroxypropyl) sulfone Chemical Properties, Uses, Production
Synthesis
505-10-2
2058-49-3
General procedure for the synthesis of 3-methylsulfonyl-1-propanol from 3-methylthiopropanol: 3-methylthiopropanol (200 g, 1900 mmol) was dissolved in dichloromethane (2000 ml). The reaction mixture was cooled to 0°C. An 85% aqueous solution of m-chloroperoxybenzoic acid (970 g, 5700 mmol) was added in batches while maintaining the temperature between 0 and 5 °C. After the addition was completed, the reaction mixture was slowly warmed to 25 °C and the reaction was stirred at this temperature for 15 hours. After completion of the reaction, the mixture was filtered through a diatomaceous earth pad. The filtrate was purified by fast column chromatography (eluent: petroleum ether/ethyl acetate = 3:1, followed by ethyl acetate/methanol = 10:1) to afford the target product 3-methylsulfonyl-1-propanol (75 g, 29% yield).
References
[1] Patent: WO2012/80447, 2012, A1. Location in patent: Page/Page column 18
[2] Patent: WO2012/80450, 2012, A1. Location in patent: Page/Page column 27
[3] Patent: WO2012/80449, 2012, A1. Location in patent: Page/Page column 20
[4] Patent: US2013/267555, 2013, A1. Location in patent: Paragraph 0092-0094
[5] Patent: WO2013/186335, 2013, A1. Location in patent: Page/Page column 78; 79
Methyl-(3-hydroxypropyl) sulfone Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| GUANGZHOU AANPHARM TECHNOLOGY CO.,LTD | 020-86211473 13925088720 | linda@aanpharm.com | China | 3641 | 58 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| Letopharm Limited | +86-21-5821 5861 | sales@letopharm.com | China | 70 | 55 |
| Shanghai Raise Chemical Technology Co.,Ltd | 15026594951 | rs@raise-chem.com | China | 4905 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Hangzhou J&H Chemical Co., Ltd. | 0571-87396432 | sales@jhechem.com | China | 14905 | 59 |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9781 | 50 |
View Latest Price from Methyl-(3-hydroxypropyl) sulfone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-14 | METHYL-(3-HYDROXYPROPYL) SULFONE
2058-49-3
|
1kg | 97% | 1000kg/month | Shanghai Wish Pharma Co., Ltd | ||
 |
2024-10-22 | METHYL-(3-HYDROXYPROPYL) SULFONE
2058-49-3
|
$1.00 | 1g | 85.0-99.8% | 20ton | Career Henan Chemica Co |
-
- METHYL-(3-HYDROXYPROPYL) SULFONE
2058-49-3
- 97%
- Shanghai Wish Pharma Co., Ltd
-
- METHYL-(3-HYDROXYPROPYL) SULFONE
2058-49-3
- $1.00
- 85.0-99.8%
- Career Henan Chemica Co
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