Ethyl 2-aminoindole-3-carboxylate
- CAS No.
- 6433-72-3
- Chemical Name:
- Ethyl 2-aminoindole-3-carboxylate
- Synonyms
- 2-amino-, ethyl ester;Ethyl 2-aminoindole-3-carboxylate;ethyl 2-aminoindoline-3-carboxylate;2-AMINOINDOLE-3-CARBOXYLIC ETHYL ESTER;ETHYL 2-AMINOINDOLE-3-CARBOXYLATE USP/EP/BP;2-AMINOINDOLE-3-CARBOXYLIC ACID, ETHYL ESTER;1H-Indole-3-carboxylicacid, 2-amino-, ethyl ester;1H-Indole-3-carboxylicacid,2-amino-,ethylester(9CI);2-amino-2,3-dihydro-1H-indole-3-carboxylic acid ethyl ester
- CBNumber:
- CB8189183
- Molecular Formula:
- C11H12N2O2
- Molecular Weight:
- 204.23
- MDL Number:
- MFCD01568663
- MOL File:
- 6433-72-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H335-H315-H319 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 |
Ethyl 2-aminoindole-3-carboxylate price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-E898525-500MG | Ethyl 2-Aminoindole-3-carboxylate | 6433-72-3 | 500mg | $179 | 2026-06-03 | Buy |
| TRC | TRC-E898525-2G | Ethyl 2-Aminoindole-3-carboxylate | 6433-72-3 | 2g | $549 | 2026-06-03 | Buy |
| TRC | TRC-E898525-1G | Ethyl 2-Aminoindole-3-carboxylate | 6433-72-3 | 1g | $300 | 2026-06-03 | Buy |
| Matrix Scientific | 303800 | Ethyl 2-amino-1H-indole-3-carboxylate | 6433-72-3 | 250.00mg | $58 | 2026-05-19 | Buy |
| Matrix Scientific | 303800 | Ethyl 2-amino-1H-indole-3-carboxylate | 6433-72-3 | 1.00g | $89 | 2026-05-19 | Buy |
Ethyl 2-aminoindole-3-carboxylate Chemical Properties, Uses, Production
Chemical Properties
Off-White Crystalline Solid
Uses
Ethyl 2-Aminoindole-3-carboxylate (cas# 6433-72-3) is a compound useful in organic synthesis.
Synthesis
65548-02-9
6433-72-3
Step 2. Synthesis of ethyl 2-amino-1H-indole-3-carboxylate [Formula 12-3]: Ethyl 2-cyano-2-(2-nitrophenyl)acetate [Formula 12-2] (16 g, 68.315 mmol) was dissolved in acetic acid (200 mL), and zinc powder (17.86 g, 273.25 mmol) was added, and the reaction was stirred for 24 hr at 65 °C. Upon completion of the reaction, the zinc powder was removed by diatomaceous earth filtration and the acetic acid was removed by distillation under reduced pressure to give a solid product. The resulting solid was dissolved in excess dichloromethane and subsequently crystallized by addition of hexane to give ethyl 2-aminoindole-3-carboxylate (6 g, 44% yield).
References
[1] Chinese Journal of Chemistry, 2013, vol. 31, # 2, p. 263 - 266
[2] Patent: WO2013/62344, 2013, A1. Location in patent: Page/Page column 28; 99
[3] Patent: US2014/315889, 2014, A1. Location in patent: Paragraph 0472-0474
[4] Tetrahedron Letters, 2006, vol. 47, # 2, p. 159 - 162
[5] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 20, p. 6123 - 6133,11
Ethyl 2-aminoindole-3-carboxylate Preparation Products And Raw materials
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| Supplier | Tel | Country | ProdList | Advantage | |
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