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ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE

CAS No.
721-63-1
Chemical Name:
ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE
Synonyms
Penbutolol-d9A;2-[4-(trifluoroMethyl)phenyl]butanoate;Ethyl 4-(trifluoromethyl)benzeneacetate;ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE;ethyl 2-(4-(trifluoromethyl)phenyl)acetate;REF DUPL: Ethyl 4-(trifluoromethyl)phenylacetate;4-(Trifluoromethyl)benzeneacetic acid ethyl ester;(4-TRIFLUOROMETHYL-PHENYL)-ACETIC ACID ETHYL ESTER;Benzeneacetic acid, 4-(trifluoroMethyl)-, ethyl ester
CBNumber:
CB8190406
Molecular Formula:
C11H11F3O2
Molecular Weight:
232.2
MDL Number:
MFCD07779351
MOL File:
721-63-1.mol
MSDS File:
SDS
Last updated:2026-05-28 03:03:54
Product description Number Pack Size Price
Ethyl 4-(Trifluoromethyl)phenylacetate E1152 1G $67
Ethyl 4-(Trifluoromethyl)phenylacetate E1152 5G $201
Ethyl 4-(trifluoromethyl)phenylacetate 98% PC3679 250mg $21
Ethyl 4-(trifluoromethyl)phenylacetate 98% PC3679 1g $24
Ethyl 4-(trifluoromethyl)phenylacetate 98% PC3679 5g $30
More product size

ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE Properties

Melting point 34-35 °C
Boiling point 104-105 °C(Press: 7 Torr)
Density 1.207
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol
form Solid
color Colorless

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39
HS Code  2916340000
NFPA 704
1
2 0

ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE price More Price(68)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical E1152 Ethyl 4-(Trifluoromethyl)phenylacetate 721-63-1 1G $67 2026-04-30 Buy
TCI Chemical E1152 Ethyl 4-(Trifluoromethyl)phenylacetate 721-63-1 5G $201 2026-04-30 Buy
Apolloscientific PC3679 Ethyl 4-(trifluoromethyl)phenylacetate 98% 721-63-1 250mg $21 2026-06-04 Buy
Apolloscientific PC3679 Ethyl 4-(trifluoromethyl)phenylacetate 98% 721-63-1 1g $24 2026-06-04 Buy
Apolloscientific PC3679 Ethyl 4-(trifluoromethyl)phenylacetate 98% 721-63-1 5g $30 2026-06-04 Buy
Product number Packaging Price Buy
E1152 1G $67 Buy
E1152 5G $201 Buy
PC3679 250mg $21 Buy
PC3679 1g $24 Buy
PC3679 5g $30 Buy

ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE Chemical Properties,Uses,Production

Synthesis

4-Bromobenzotrifluoride

402-43-7

Ethyl potassium malonate

6148-64-7

ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE

721-63-1

General procedure: Under standard Schlenk operating conditions, the reaction system is first evacuated and backfilled three times with dry pure nitrogen. To a pre-dried Schlenk tube fitted with a magnetic stirring bar, palladium catalyst (see Tables 1 to 4 for specific types and amounts), ligand (see Tables 1 to 4), N,N-dimethylpyridin-4-amine (DMAP, see Tables 1 to 4), and monoethyl malonate potassium salt (see Tables 1 to 4) are added sequentially. Subsequently, the reaction tube was evacuated and backfilled with argon, and this process was repeated three times. Under argon protection, p-bromobenzotrifluoride (see Tables 1 through 4) and an appropriate amount of solvent (see Tables 1 through 4) were added via syringe. The reaction tube was sealed and stirred for 10 minutes at room temperature. Afterwards, the reaction tube is connected to a Schlenk line pre-filled with argon and placed in an oil bath preheated to 140-150°C and the reaction is stirred for 20-25 hours. After completion of the reaction, the reaction was cooled to room temperature, the reaction mixture was diluted with ether and the yield of ethyl 4-(trifluoromethyl)phenylacetate was determined by gas chromatography using 1,3-dimethoxybenzene as an internal standard.

References

[1] Tetrahedron, 2012, vol. 68, # 9, p. 2113 - 2120

ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE Preparation Products And Raw materials

Global( 143)Suppliers
Supplier Tel Email Country ProdList Advantage
Changzhou Ansciep Chemical Co., Ltd.
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Alchem Pharmtech,Inc.
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CONIER CHEM AND PHARMA LIMITED
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career henan chemical co
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View Lastest Price from ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE pictures 2021-07-13 ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE
721-63-1
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE pictures 2021-07-10 ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE
721-63-1
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE pictures 2019-12-31 ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE
721-63-1
$1.00 1KG 99% 200kg Career Henan Chemical Co

ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE Spectrum

ETHYL 4-(TRIFLUOROMETHYL)PHENYL ACETATE ethyl 2-(4-(trifluoromethyl)phenyl)acetate REF DUPL: Ethyl 4-(trifluoromethyl)phenylacetate 4-(Trifluoromethyl)benzeneacetic acid ethyl ester 2-[4-(trifluoroMethyl)phenyl]butanoate Benzeneacetic acid, 4-(trifluoroMethyl)-, ethyl ester (4-TRIFLUOROMETHYL-PHENYL)-ACETIC ACID ETHYL ESTER Ethyl 4-(trifluoromethyl)benzeneacetate Penbutolol-d9A 721-63-1