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5-Bromo-2-phenoxypyrimidine

CAS No.
257280-25-4
Chemical Name:
5-Bromo-2-phenoxypyrimidine
Synonyms
5-Bromo-2-phenoxypyrimidine;Pyrimidine, 5-bromo-2-phenoxy-;5-BROMO-2-PHENOXYPYRIMIDINE ISO 9001:2015 REACH
CBNumber:
CB8203520
Molecular Formula:
C10H7BrN2O
Molecular Weight:
251.08
MDL Number:
MFCD03646346
MOL File:
257280-25-4.mol
Last updated:2026-09-12 18:55:25

5-Bromo-2-phenoxypyrimidine Properties

storage temp. Sealed in dry,Room Temperature

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
Risk Statements  43
Safety Statements  36/37

5-Bromo-2-phenoxypyrimidine price More Price(53)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AstaTech 30001 5-BROMO-2-PHENOXYPYRIMIDINE 97% 257280-25-4 5G $35 2026-04-30 Buy
AstaTech 30001 5-BROMO-2-PHENOXYPYRIMIDINE 97% 257280-25-4 25G $164 2026-04-30 Buy
Activate Scientific AS30450 5-Bromo-2-phenoxypyrimidine 97% 257280-25-4 1g $27 2026-06-04 Buy
Activate Scientific AS30450 5-Bromo-2-phenoxypyrimidine 97% 257280-25-4 5g $56 2026-06-04 Buy
Activate Scientific AS30450 5-Bromo-2-phenoxypyrimidine 97% 257280-25-4 25g $233 2026-06-04 Buy
Product number Packaging Price Buy
30001 5G $35 Buy
30001 25G $164 Buy
AS30450 1g $27 Buy
AS30450 5g $56 Buy
AS30450 25g $233 Buy

5-Bromo-2-phenoxypyrimidine Chemical Properties, Uses, Production

Synthesis

5-Bromo-2-iodopyrimidine

183438-24-6

Phenol

108-95-2

5-BROMO-2-PHENOXYPYRIMIDINE

257280-25-4

Step A: Synthesis of 5-bromo-2-phenoxypyrimidine 5-Bromo-2-iodopyrimidine (Bridge Organics, 1.01 g, 3.57 mmol), phenol (Aldrich, 3.35 g, 35.7 mmol) and potassium carbonate (Aldrich, 4.93 g, 35.7 mmol) were mixed under nitrogen protection and the reaction was stirred for 4 hr at 165°C. Upon completion of the reaction, the mixture was cooled to room temperature, followed by liquid-liquid partition extraction with ethyl acetate (250 mL) and 1N hydrochloric acid (4 × 200 mL). The organic phase was washed with 1N hydrochloric acid until the aqueous phase was colorless. The organic phase was separated and washed sequentially with water (100 mL) and saturated saline (100 mL). The organic layer was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give an orange oily crude product (1.1 g). The crude product was purified by fast silica gel column chromatography using an 80 g Silicycle silica gel column with 10% ethyl acetate in hexane solution as eluent to afford the target compound 5-bromo-2-phenoxypyrimidine as a white solid (0.82 g, 92% yield). Thin layer chromatography (TLC) analysis showed an Rf value of 0.51 (unfolding agent: hexane-ethyl acetate, 8:2 v/v). Product characterization data: 1H-NMR (400 MHz, CDCl3) δ 8.56 (s, 2H), 7.46-7.41 (m, 2H), 7.30-7.24 (m, 1H), 7.20-7.16 (m, 2H); Mass spectrum (APCI+) m/z 252.9 (M + 1).

References

[1] Patent: US2010/75990, 2010, A1. Location in patent: Page/Page column 40
[2] Patent: CN108069974, 2018, A. Location in patent: Paragraph 0194-0196

5-Bromo-2-phenoxypyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

5-Bromo-2-phenoxypyrimidine Suppliers

Global Suppliers ( 105)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Jinan Trio PharmaTech Co., Ltd. 0531-88811783 sales@trio-pharmatech.com China 1856 62
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9510 58
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56

View Latest Price from 5-Bromo-2-phenoxypyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-BROMO-2-PHENOXYPYRIMIDINE  pictures 2026-08-20 5-BROMO-2-PHENOXYPYRIMIDINE
257280-25-4
$1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
5-BROMO-2-PHENOXYPYRIMIDINE pictures 2021-07-13 5-BROMO-2-PHENOXYPYRIMIDINE
257280-25-4
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
5-BROMO-2-PHENOXYPYRIMIDINE pictures 2021-07-10 5-BROMO-2-PHENOXYPYRIMIDINE
257280-25-4
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
Pyrimidine, 5-bromo-2-phenoxy- 5-BROMO-2-PHENOXYPYRIMIDINE ISO 9001:2015 REACH 5-Bromo-2-phenoxypyrimidine 257280-25-4 Heterocycle-Pyrimidine series