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α-Ergocryptine

α-Ergocryptine structure

CAS No.: 511-09-1

Chemical Name:: α-Ergocryptine

Synonyms: ergocryptine;ergokryptine;ALPHA-ERGOCRYPTINE;Bromocriptine EP Impurity B;Ergocrypyine;Ergocriptine;A-ergocryptine;α-Ergocryptine;alpha-ergokryptine;9,10-Dihydro-&beta

CBNumber:: CB8205993

Molecular Formula:: C32H41N5O5

Molecular Weight:: 575.7

MDL Number:: MFCD26143009

MOL File:: 511-09-1.mol

MSDS File:: SDS

Last updated:2026-05-28 03:29:41

Product description	Number	Pack Size	Price
α-Ergocryptine	TRC-E597500-5MG	5mg	$7690
α-Ergocryptine	TRC-E597500-1MG	1mg	$1932
α-Ergocryptine	TRC-E597500-0.25MG	0.25mg	$693
a-Ergocryptine	FE22782	50mg	$23364
α-Ergocryptine	E597500	5mg	$5775
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α-Ergocryptine Properties

Melting point	152-154°C
alpha	D20 -120° (pyridine); -198° (chloroform)
Boiling point	636.59°C (rough estimate)
Density	1.1762 (rough estimate)
refractive index	1.7500 (estimate)
storage temp.	−20°C
solubility	45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.3 mg/mL
form	Solid
pka	9.61±0.60(Predicted)
color	Pale Yellow to Pale Beige
Stability	Hygroscopic
InChIKey	YDOTUXAWKBPQJW-YBALXUQENA-N
SMILES	[C@@]12(O)O[C@@](C(C)C)(NC(=O)[C@H]3CN(C4CC5=CNC6=CC=CC(=C56)C4=C3)C)C(=O)N1[C@@H](CC(C)C)C(=O)N1CCCC21 \|&1:0,3,10,30,r\|
EWG's Food Scores	1
FDA UNII	6WFB60157B

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS08
Signal word	Warning
Hazard statements	H332-H361-H312-H302-H362
Precautionary statements	P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501-P201-P260-P263-P264-P270-P308+P313-P201-P202-P281-P308+P313-P405-P501-P280-P302+P352-P312-P322-P363-P501
Hazard Codes	Xn
Risk Statements	62
Safety Statements	36/37
RIDADR	UN 1544 6.1/PG 3
WGK Germany	3
RTECS	KE1400000
HazardClass	6.1(b)
PackingGroup	III
REACH Registrations	Active

α-Ergocryptine price More Price(7)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	TRC-E597500-5MG	α-Ergocryptine	511-09-1	5mg	$7690	2026-06-03	Buy
TRC	TRC-E597500-1MG	α-Ergocryptine	511-09-1	1mg	$1932	2026-06-03	Buy
TRC	TRC-E597500-0.25MG	α-Ergocryptine	511-09-1	0.25mg	$693	2026-06-03	Buy
Biosynth	FE22782	a-Ergocryptine	511-09-1	50mg	$23364	2026-06-04	Buy
TRC	E597500	α-Ergocryptine	511-09-1	5mg	$5775	2021-12-16	Buy

Product number	Packaging	Price	Buy
TRC-E597500-5MG	5mg	$7690	Buy
TRC-E597500-1MG	1mg	$1932	Buy
TRC-E597500-0.25MG	0.25mg	$693	Buy
FE22782	50mg	$23364	Buy
E597500	5mg	$5775	Buy

α-Ergocryptine Chemical Properties,Uses,Production

Chemical Properties

Pale Yellow Solid

Uses

α-Ergocryptine is an ergopeptine and one of the ergot alkaloids. An impurity of 2-Bromo α-Ergocryptine Mesylate (B682600).

Uses

An impurity of 2-Bromo α-Ergocriptine Mesylate (B682600).

Definition

ChEBI: Ergotaman bearing hydroxy, isopropyl, and 2-methylpropyl groups at the 12', 2' and 5' positions, respectively, and oxo groups at positions 3', 6', and 18. It is a natural ergot alkaloid. Ergocryptine discussed in the literature prior to 1967, when b ta-ergocryptine was separated from alpha-ergocryptine, is now referred to as alpha-ergocryptine.

General Description

One of the biologically most important ergot alkaloids is α-ergocryptine. Its semisynthetic derivative, the so-called bromocryptine, is one of the most widely used drugs in this family (e.g., as a prolactin inhibitor or an anti-Parkinsonian)[2].

Toxicology

A study describes the metabolic changes observed in a dietary subacute toxicity experiment with the ergot alkaloid α-ergocryptine in Sprague±Dawley rats. The rats were fed 0, 4, 20, 100 or 500 mg ergocryptine/kg diet for 28±32 days (equal to 0, 0.36, 1.7, 8.9 and 60 mg ergocryptine/kg body weight/day for females and 0, 0.34, 1.4, 6.6 and 44 mg ergocryptine/kg body weight/day for males). Total cholesterol and high-density lipoprotein (HDL)-cholesterol was decreased dose-dependently in females, but the ratio HDL-cholesterol/total cholesterol was only decreased at 20 mg/kg body weight. Triglycerides and glucose concentrations were decreased in the highest dose groups of both sexes. Serum urea concentrations were increased in the 20, 100 and 500 mg/kg dose groups. Insulin, glucagon and liver glycogen were increased in the highest dose group at the end of the study when the animals were allowed to eat prior to blood sampling and necropsy. Prolactin, T4 and FT4 were decreased in the 20, 100 and 500 mg/kg dose groups of both sexes. Follicle-stimulating hormone (FSH) was decreased in the 20, 100 and 500 mg/kg female dose groups and luteinizing hormone (LH) was increased in the 20, 100 and 500 mg/kg male dose groups[1].

Purification Methods

It crystallises with solvent of crystallisation, from acetone, *benzene or methanol. [Stadler et al. Helv Chim Acta 52 1549 1969, Beilstein 25 III/IV 964, 27 II 860.]

References

[1] G.B Janssen . “Subacute toxicity of α-ergocryptine in Sprague–Dawley rats. 1: general toxicological effects.” Food and Chemical Toxicology 38 8 (2000): Pages 679-688.
[2] I. Moldvai. “Enantioefficient Synthesis of α-Ergocryptine: First Direct Synthesis of (+)-Lysergic Acid (I).” ChemInform 8 1 (2005).

α-Ergocryptine Preparation Products And Raw materials

Raw materials

Preparation Products

α-Ergocryptine Suppliers

Global( 71)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Moxin Chemicals	+86-17320513646 +8617320513646	anna@molcoo.com	China	10000	58
Guangzhou Tosun Pharmaceutical Ltd	+86-020-61855200-902 +8618124244216	info@upharm.cn	China	897	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21585	55
Neostar United (Changzhou) Industrial Co., Ltd.	+86-0519-85551759 +8613506123987	marketing1@neostarunited.com	China	8828	58
RongNa Biotechnology Co.,Ltd	+86-86-13583358881 +8618560316533	Brad@rongnabiotech.com	China	3372	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1059@dideu.com	China	29094	58
Zhuoer Chemical Co., Ltd	02120970332; +8613524231522	sales@zhuoerchem.com	China	2904	58
PT CHEM GROUP LIMITED	+86-85511178;	peter68@ptchemgroup.com	China	35425	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49897	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	43333	58

Supplier	Advantage
Moxin Chemicals	58
Guangzhou Tosun Pharmaceutical Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Neostar United (Changzhou) Industrial Co., Ltd.	58
RongNa Biotechnology Co.,Ltd	58
Dideu Industries Group Limited	58
Zhuoer Chemical Co., Ltd	58
PT CHEM GROUP LIMITED	58
GIHI CHEMICALS CO.,LIMITED	58
HANGZHOU LEAP CHEM CO., LTD.	58

View Lastest Price from α-Ergocryptine manufacturers

Update time	Product	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-24	ALPHA-ERGOCRYPTINE 511-09-1		0.99		RongNa Biotechnology Co.,Ltd
2025-12-19	Bromocriptine EP Impurity B 511-09-1	5mg	95%+	1000mg	Guangzhou Tosun Pharmaceutical Ltd
2025-12-16	Bromocriptine Impurity 511-09-1	10mg	98	10000000	Moxin Chemicals

ALPHA-ERGOCRYPTINE
511-09-1
0.99
RongNa Biotechnology Co.,Ltd

Bromocriptine EP Impurity B
511-09-1
95%+
Guangzhou Tosun Pharmaceutical Ltd

Bromocriptine Impurity
511-09-1
98
Moxin Chemicals

511-09-1(α-Ergocryptine)Related Search:

Ergotaman-3',6',18-trione, 2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, (2'β,5'α,8α)- (9CI) BroMocriptine IMpurity G BroMocriptine-13C-d3 BroMocriptine IMpurity F Ergoline-8-carboxylic acid, 2-bromo-9,10-didehydro-6-methyl-, (8β)-

Bromocriptine (8S)-2-BroMo α-Ergocryptine Bromocriptine mesylate BroMocriptine IMpurity E beta-ergocryptine

Bromocriptine Impurity 2 Bromocriptine Impurity A (Mixture of Diastereomers) DIHYDROERGOCRISTINE MESYLATE ERGTOXIN ALPHA-ERGOCRYPTINE

Mergocriptine 1-Bromo-α-ergocryptine methane Sulfonate ergocryptine methanesulfonate

1of4

12’-hydroxy-2’-(1-methylethyl)-5’-alpha-(2-methylpropyl)ergotaman-3’,6’,18-t 9,10-Dihydro-&beta alpha-ergokryptine A-ergocryptine 12'-hydroxy-5'alpha-isobutyl-2'-isopropylergotaman-3',6',18-trione ERGOCRYPTINE95%,98% 12μ-Hydroxy-2μ-(1-methylethyl)-5μ-α-(2-methylpropyl)ergotaman-3μ,6μ,18-trione 12'-Hydroxy-2'-isopropyl-5'α-isobutylergotaman-3',6',18-trione A-ERGOCRYPTINE ERGOT ALKALOID Ergocryptine Ergokryptine ErgotaMan-3',6',18-trione,12'-hydroxy-2'-(1-Methylethyl)-5'-(2-Methylpropyl)-, (5'a)- (R)-9,10-Dihydro-&beta Ergotaman-3',6',18-trione, 12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, (5'α)- Bromocriptine Impurity 2（Bromocriptine Mesylate EP Impurity B) α-Ergocryptine Ergocrypyine ALPHA-ERGOCRYPTINE USP/EP/BP Bromocriptine mesilate EP Impurity B (6aR,9R)-N-[(2R,5S,10aS,10bS)-10b-hydroxy-2-(1-methylethyl)-5-(2-methylpropyl)-3,6-dioxooctahydro-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide (α-ergocryptine), (6aR,9R)-N-((2R,5S,10aS,10bS)-10b-hydroxy-5-isobutyl-2-isopropyl-3,6-dioxooctahydro-2H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide Ergocriptine Bromocryptine EP Impurity B (α-Ergocryptine) Cilnidipine Impurity 16 12'-hydroxy-5'α-isobutyl-2'-isopropylergotaman-3',6',18-trione ALPHA-ERGOCRYPTINE Bromocriptine EP Impurity B ergokryptine ergocryptine 511-09-1 3086-91-8 205448-66-5 C32H41N5O5 Aromatics Heterocycles Impurities Inhibitors Intermediates & Fine Chemicals Pharmaceuticals