ChemicalBook >> CAS DataBase List >>(6R)-6,7,8,9-Tetrahydro-6β,7α-dihydroxy-1,6-dimethylphenanthro[1,2-b]furan-10,11-dione

(6R)-6,7,8,9-Tetrahydro-6β,7α-dihydroxy-1,6-dimethylphenanthro[1,2-b]furan-10,11-dione

(6R)-6,7,8,9-Tetrahydro-6β,7α-dihydroxy-1,6-dimethylphenanthro[1,2-b]furan-10,11-dione structure

CAS No.: 97465-71-9

Chemical Name:: (6R)-6,7,8,9-Tetrahydro-6β,7α-dihydroxy-1,6-dimethylphenanthro[1,2-b]furan-10,11-dione

Synonyms: Tanshindiol C;(-)-Tanshindiol C;(6R,7R)-6,7,8,9-Tetrahydro-6,7-dihydroxy-1,6-dimethylphenanthro[1,2-b]furan-10,11-dione;Phenanthro[1,2-b]furan-10,11-dione, 6,7,8,9-tetrahydro-6,7-dihydroxy-1,6-dimethyl-, (6R,7R)-(-)-

CBNumber:: CB82373065

Molecular Formula:: C18H16O5

Molecular Weight:: 312.31664

MDL Number:: MFCD21333424

MOL File:: 97465-71-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:38

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(6R)-6,7,8,9-Tetrahydro-6β,7α-dihydroxy-1,6-dimethylphenanthro[1,2-b]furan-10,11-dione Properties

Boiling point	561.5±50.0 °C(Predicted)
Density	1.436±0.06 g/cm3(Predicted)
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	powder
pka	13.76±0.40(Predicted)
color	Red

(6R)-6,7,8,9-Tetrahydro-6β,7α-dihydroxy-1,6-dimethylphenanthro[1,2-b]furan-10,11-dione price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0090502	Tanshindiol C 98.47%	97465-71-9	1mg	$517	2026-06-04	Buy
ChemScene	CS-0090502	Tanshindiol C 98.47%	97465-71-9	5mg	$1137	2026-06-04	Buy
ChemScene	CS-0090502	Tanshindiol C 98.47%	97465-71-9	10mg	$1831	2026-06-04	Buy
aablocks	AA01RTAC	Tanshindiol C >98%	97465-71-9	1mg	$565	2026-05-31	Buy
aablocks	AA01RTAC	Tanshindiol C >98%	97465-71-9	5mg	$1202	2026-05-31	Buy

Product number	Packaging	Price	Buy
CS-0090502	1mg	$517	Buy
CS-0090502	5mg	$1137	Buy
CS-0090502	10mg	$1831	Buy
AA01RTAC	1mg	$565	Buy
AA01RTAC	5mg	$1202	Buy

(6R)-6,7,8,9-Tetrahydro-6β,7α-dihydroxy-1,6-dimethylphenanthro[1,2-b]furan-10,11-dione Chemical Properties, Uses, Production

Description

Tanshindiol C exhibits most powerful cytotoxic effects against tested tumor cells. Tanshinones plays significant roles in the inhibition and induction of several CYP450 isozymes.

Uses

Tanshindiol C is a S-adenosylmethionine-competitive EZH2 (Histone Methyltransferase) inhibitor with an IC50 of 0.55 μM for inhibiting the methyltransferase activity. Tanshindiol C is also an activator of both Nrf2 and Sirtuin 1 (Sirt1) in macrophages. Tanshindiol C possesses anti-cancer activity, and can be used for atherosclerosis research[1][2].

target

P450 (e.g. CYP17)

IC 50

EZH2: 0.55 μM (IC₅₀); SIRT1

References

[1] Yuyu Yang, et al. Tanshindiol C inhibits oxidized low-density lipoprotein induced macrophage foam cell formation via a peroxiredoxin 1 dependent pathway. Biochim Biophys Acta Mol Basis Dis. 2018 Mar;1864(3):882-890. DOI:10.1016/j.bbadis.2017.12.033
[2] Jimin Woo, et al. Biological evaluation of tanshindiols as EZH2 histone methyltransferase inhibitors. Bioorg Med Chem Lett. 2014 Jun 1;24(11):2486-92. DOI:10.1016/j.bmcl.2014.04.010

(6R)-6,7,8,9-Tetrahydro-6β,7α-dihydroxy-1,6-dimethylphenanthro[1,2-b]furan-10,11-dione Preparation Products And Raw materials

Raw materials

Preparation Products

(6R)-6,7,8,9-Tetrahydro-6β,7α-dihydroxy-1,6-dimethylphenanthro[1,2-b]furan-10,11-dione Suppliers

Global Suppliers ( 35)

Supplier	Tel	Email	Country	ProdList	Advantage
Sichuan Wei Keqi Biological Technology Co., Ltd.	028-81700200 18116577057	3003855609@qq.com	China	7717	56
Wuxi Zhongkun Biochemical Technology Co., Ltd.	0510-85629785 18013409632;	sales@reading-chemicals.com	China	15165	58
Wuhan ChemFaces Biochemical Co., Ltd.	18607101326 15172504745	aileen@chemfaces.com	China	6904	55
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8435	60
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Shanghai ChengShao Biological Technology Co., Ltd.	021-61847300 13341622919	shcss01@163.com	China	4806	58
Chengdu Push Bio-Technology Co., Ltd.	028-85370565-229 18080489829	18080489829@163.com	China	8379	60
Nanjing Digger Medical Technology Co. Ltd.	025-025-51191215 18013836722	2399235533@qq.com	China	4932	58
Zhejiang Lianshuo Biotechnology Co., Ltd.	18616526224	lianshuo@vip.126.com	China	9605	58
Guangzhou Younan Technology Co., Ltd	020-82000279 18988941452	YN_research@163.com	China	2984	58

Supplier	Advantage
Sichuan Wei Keqi Biological Technology Co., Ltd.	56
Wuxi Zhongkun Biochemical Technology Co., Ltd.	58
Wuhan ChemFaces Biochemical Co., Ltd.	55
EMMX Biotechnology LLC	60
Shanghai YuanYe Biotechnology Co., Ltd.	60
Shanghai ChengShao Biological Technology Co., Ltd.	58
Chengdu Push Bio-Technology Co., Ltd.	60
Nanjing Digger Medical Technology Co. Ltd.	58
Zhejiang Lianshuo Biotechnology Co., Ltd.	58
Guangzhou Younan Technology Co., Ltd	58

97465-71-9 ((6R)-6,7,8,9-Tetrahydro-6β,7α-dihydroxy-1,6-dimethylphenanthro[1,2-b]furan-10,11-dione) Related Search:

2,2-Dimethyl-1,3-propanediol Dihydrotanshinone I 7,8-Dihydro-1,6,6-trimethylphenanthro[1,2-b]furan-9,10,11(6H)-trione Tanshinol B 3alpha-Hydroxytanshinone IIA

Hydroxytanshinone IIA

1of2

(6R,7R)-6,7,8,9-Tetrahydro-6,7-dihydroxy-1,6-dimethylphenanthro[1,2-b]furan-10,11-dione Phenanthro[1,2-b]furan-10,11-dione, 6,7,8,9-tetrahydro-6,7-dihydroxy-1,6-dimethyl-, (6R,7R)-(-)- (-)-Tanshindiol C Tanshindiol C 97465-71-9