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2-Chloro-1,3-dimethylbenzene

2-Chloro-1,3-dimethylbenzene Structure
2-Chloro-1,3-dimethylbenzene structure
CAS No.
6781-98-2
Chemical Name:
2-Chloro-1,3-dimethylbenzene
Synonyms
2-Chloroxylene;1-Bromo-m-xylene;2-CHLORO-M-XYLENE;m-Xylene, 2-chloro-;2-Chloro-m-xylene,98%;2-Chloro-m-xylene,99%;2-Chloro-m-xylene >2,6-DIMETHYL CHLOROBENZENE;2,6-Dimethylphenyl chloride;2,6-DIMETHYLDICHLOROBENZENE
CBNumber:
CB8249483
Molecular Formula:
C8H9Cl
Molecular Weight:
140.61
MDL Number:
MFCD00000565
MOL File:
6781-98-2.mol
MSDS File:
SDS
Last updated:2026-05-28 04:23:25
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2-Chloro-1,3-dimethylbenzene Properties

Melting point -36 °C (lit.)
Boiling point 182-183 °C (lit.)
Density 1.061 g/mL at 25 °C (lit.)
refractive index n20/D 1.527(lit.)
Flash point 146 °F
storage temp. Sealed in dry,Room Temperature
form liquid
Specific Gravity 1.061
Appearance Colorless to light yellow Liquid
Water Solubility Not miscible or difficult to mix with water.
BRN 2040954
InChI 1S/C8H9Cl/c1-6-4-3-5-7(2)8(6)9/h3-5H,1-2H3
InChIKey VDXLAYAQGYCQEO-UHFFFAOYSA-N
SMILES Cc1cccc(C)c1Cl
CAS DataBase Reference 6781-98-2(CAS DataBase Reference)
NIST Chemistry Reference Benzene, 2-chloro-1,3-dimethyl-(6781-98-2)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21
Safety Statements  26-36/37/39-36/37-23
RIDADR  1993
WGK Germany  3
HazardClass  IRRITANT
HS Code  2906290090
Storage Class 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
2
2 0

2-Chloro-1,3-dimethylbenzene price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 276308 2-Chloro-1,3-dimethylbenzene 97% 6781-98-2 25g $101 2023-01-07 Buy
TCI Chemical C2164 2-Chloro-m-xylene 6781-98-2 25G $67 2026-04-30 Buy
Biosynth GAA78198 2-Chloro-m-xylene 6781-98-2 100g $250 2026-06-04 Buy
Apolloscientific OR7643 2-Chloro-1,3-dimethylbenzene 99% 6781-98-2 1g $21 2026-06-04 Buy
Apolloscientific OR7643 2-Chloro-1,3-dimethylbenzene 99% 6781-98-2 25g $109 2026-06-04 Buy
Product number Packaging Price Buy
276308 25g $101 Buy
C2164 25G $67 Buy
GAA78198 100g $250 Buy
OR7643 1g $21 Buy
OR7643 25g $109 Buy

2-Chloro-1,3-dimethylbenzene Chemical Properties, Uses, Production

Chemical Properties

Clear colourless to light yellow liquid

Uses

It is employed as intermediate for pharmaceutical.

General Description

Suzuki coupling reaction of 2-chloro-1,3-dimethylbenzene with arylboronic acids has been investigated. 2-Chloro-1,3-dimethylbenzene undergoes palladium-catalyzed cyanation reaction to afford 2,6-dimethyl benzonitrile.

Synthesis

(2,6-dimethylphenyl) chloroformate

876-99-3

2-Chlorotoluene

95-49-8

2-Chloro-1,3-dimethylbenzene

6781-98-2

In a 1 L four-neck flask, 110.8 g of phenyl 2,6-dimethyl chloroformate (cas:876-99-3) was slowly added dropwise to the reaction system, followed by 110.8 g of anhydrous aluminum trichloride. The reaction system was warmed up to 80 °C and then 554 g (3.0 mol) of phenyl 2,6-dimethyl chloroformate was added. During the addition, the reaction was exothermic and the temperature of the system was gradually increased to 100~110 °C. The reaction temperature was maintained at 100~110°C, and the holding time was continued for 3.0 hours after the addition was completed. Samples were taken and analyzed during the reaction, and when the remaining amount of raw material was 15~17%, the target products 2,6-dimethylchlorobenzene and 2-chlorotoluene were generated in 40% each. After the reaction was completed, the vacuum of the system was adjusted to 20~25 mbar, and the fractions with boiling points of 80~85 °C were collected. Finally, 185 g of 2,6-dimethylchlorobenzene liquid product was obtained, which was analyzed by gas chromatography (GC) with 99.0% purity and 43.8% yield.

References

[1] Patent: CN108530297, 2018, A. Location in patent: Paragraph 0101; 0102

2-Chloro-1,3-dimethylbenzene Preparation Products And Raw materials

Raw materials

(2,6-dimethylphenyl) chloroformate

Preparation Products

Benzenamine, N-butyl-2,6-dimethyl- 2-Chloro-1,3-benzenedicarboxylic acid 4-Chloro-m-xylene Piperazine, 1-(2,6-dimethylphenyl)-4-methyl- 2,6-dimethyl-N-p-tolylaniline

2-Chloro-1,3-dimethylbenzene Suppliers

Global Suppliers ( 189)
Supplier Tel Email Country ProdList Advantage
Yancheng Green Fluorine Fine Chemical Trading Co., Ltd 17887358129 lvfu@163.cn China 40 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
China DongFan Chemical Co.,LTD 86-0571-85151182 China 5681 66
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Supplier Advantage
Yancheng Green Fluorine Fine Chemical Trading Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Capot Chemical Co., Ltd 66
Shanghai Hanhong Scientific Co.,Ltd. 64
China DongFan Chemical Co.,LTD 66
Shandong Xiya Chemical Co., Ltd 57

View Latest Price from 2-Chloro-1,3-dimethylbenzene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloro-1,3-dimethylbenzene pictures 2026-09-02 2-Chloro-1,3-dimethylbenzene
6781-98-2
 $1.00-100.00 1KG 99% Henan Fengda Chemical Co., Ltd
2-Chloro-1,3-dimethylbenzene pictures 2026-03-20 2-Chloro-1,3-dimethylbenzene
6781-98-2
 $10.00 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
2-Chloro-1,3-dimethylbenzene pictures 2025-04-15 2-Chloro-1,3-dimethylbenzene
6781-98-2
 $10.00 1kg 99% 20ton Hebei Zhuanglai Chemical Trading Co.,Ltd

2-Chloro-1,3-dimethylbenzene Spectrum

2-Chloro-1,3-dimethylbenzene(6781-98-2)MS2-Chloro-1,3-dimethylbenzene(6781-98-2)1HNMR2-Chloro-1,3-dimethylbenzene(6781-98-2)13CNMR2-Chloro-1,3-dimethylbenzene(6781-98-2)IR12-Chloro-1,3-dimethylbenzene(6781-98-2)Raman

6781-98-2 (2-Chloro-1,3-dimethylbenzene) Related Search:

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2,6-Dimethylphenyl chloride m-Xylene, 2-chloro- 2-Chloro-m-xylene,98% 2-Chloro-1,3-dimethylbenzene 99% 2,6-DIMETHYLDICHLOROBENZENE 2-CHLORO-1,3-DIMETHYLBENZENE / 2-CHLORO-M-XYLENE 2-CHLORO-M-XYLENE 2-CHLORO-1,3-DIMETHYLBENZENE 2,6-DIMETHYL CHLOROBENZENE 1-CHLORO-2,6-DIMETHYLBENZENE 2,6-Dimethyl-1-chlorobenzene 2-Chloro-m-xylene,99% CHLORO-META-XYLENE (2-CHLORO-1,3-DIMETHYLBENZENE) 2-Chloro-1,3-dimethylbenzene99% 1-Bromo-m-xylene 2-Chloro-m-xylene > Benzene, 2-chloro-1,3-dimethyl- 2-Chloro-1,3-dimethylbenzene ISO 9001：2015 REACH 2-Chloroxylene 2-Chloro-m-xylene in isooctane 6781-98-2 Building Blocks Aryl C8 Organic Building Blocks Halogenated Hydrocarbons Halogen toluene Benzene derivates Chlorine Compounds