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2-Amino-3-bromo-6-chloropyrazine

2-Amino-3-bromo-6-chloropyrazine Structure
2-Amino-3-bromo-6-chloropyrazine structure
CAS No.
212779-21-0
Chemical Name:
2-Amino-3-bromo-6-chloropyrazine
Synonyms
104365;2-Amino-3-bromo-6-chL;3-Bromo-6-chloro-2-pyrazinamine;2-Amino-3-bromo-6-chloropyrazine;2-PyrazinaMine, 3-broMo-6-chloro-;3-Bromo-6-chloro-pyrazin-2-ylamine;2-Amino-3-bromo-6-chloropyrazine ISO 9001：2015 REACH
CBNumber:
CB82500753
Molecular Formula:
C4H3BrClN3
Molecular Weight:
208.44
MDL Number:
MFCD11044158
MOL File:
212779-21-0.mol
MSDS File:
SDS
Last updated:2026-05-28 04:29:31
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2-Amino-3-bromo-6-chloropyrazine Properties

Boiling point 299.5±35.0 °C(Predicted)
Density 1.960
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 0.05±0.10(Predicted)
Appearance Off-white to light yellow Solid
InChI InChI=1S/C4H3BrClN3/c5-3-4(7)9-2(6)1-8-3/h1H,(H2,7,9)
InChIKey BOLCKGGORFPPJC-UHFFFAOYSA-N
SMILES C1(N)=NC(Cl)=CN=C1Br

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H335-H319-H315
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362
HS Code  2933998090

2-Amino-3-bromo-6-chloropyrazine price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS22704 2-Amino-3-bromo-6-chloropyrazine 97% 212779-21-0 1g $26 2026-06-04 Buy
Activate Scientific AS22704 2-Amino-3-bromo-6-chloropyrazine 97% 212779-21-0 5g $62 2026-06-04 Buy
Activate Scientific AS22704 2-Amino-3-bromo-6-chloropyrazine 97% 212779-21-0 25g $208 2026-06-04 Buy
Activate Scientific AS22704 2-Amino-3-bromo-6-chloropyrazine 97% 212779-21-0 100g $717 2026-06-04 Buy
Matrix Scientific 119017 2-Amino-3-bromo-6-chloropyrazine 212779-21-0 1.00g $298 2026-05-18 Buy
Product number Packaging Price Buy
AS22704 1g $26 Buy
AS22704 5g $62 Buy
AS22704 25g $208 Buy
AS22704 100g $717 Buy
119017 1.00g $298 Buy

2-Amino-3-bromo-6-chloropyrazine Chemical Properties, Uses, Production

Uses

2-amino-3-bromo-6-chloropyrazine has essential applications in the pharmaceutical industry and is an important intermediate for synthesizing an anti-tumor medicament SHP2 inhibitor.

Preparation

Currently, in thepreparing 2-amino-3-bromo-6-chloropyrazine, the 2-amino-6-chloropyrazine is mainly obtained by a one-step bromination reaction. According to the method, bromine is mainly positioned at an amino para position due to the activation effect of amino; generated byproducts are mainly 2-bromo-3-chloro-5-aminopyrazine and partial dibromo byproduct 2-amino-3, 5-dibromo-6-chloropyrazine, the product 2-amino-3-bromo-6-chloro is less, the yield is low. A process for preparing 2-amino-3-bromo-6-chloropyrazine uses 3-aminopyrazine-2-carboxylate as raw material and includes such steps as chlorination, diazotization bromination, ester hydrolysis, carboxyl rearrangement and removing tert-butyloxycarbonyl.

2-Amino-3-bromo-6-chloropyrazine Preparation Products And Raw materials

Raw materials

Preparation Products

2-Amino-3-bromo-6-chloropyrazine Suppliers

Global Suppliers ( 169)
Supplier Tel Email Country ProdList Advantage
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 28-83379370 13880556291 tcy@tcypharm.com China 509 57
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Carbott PharmTech Inc. 0535-6385396 info@carbottpharm.com China 996 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
ZEROSCHEM.CO.,LTD. 10-61256048 13810278579; sales@zeroschem.com China 1400 59
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Supplier Advantage
ChengDu TongChuangYuan Pharmaceutical Co.Ltd 57
Energy Chemical 61
Carbott PharmTech Inc. 56
Capot Chemical Co., Ltd 66
Jia Xing Isenchem Co.,Ltd 66
Pure Chemistry Scientific Inc. 62
Accela ChemBio Co.,Ltd. 64
ZEROSCHEM.CO.,LTD. 59
Nanjing Chemlin Chemical Co., Ltd 64
Shanghai Hanhong Scientific Co.,Ltd. 64

View Latest Price from 2-Amino-3-bromo-6-chloropyrazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Amino-3-bromo-6-chloropyrazine pictures 2026-08-20 2-Amino-3-bromo-6-chloropyrazine
212779-21-0
 $1.10 1g 99.00% 100 Tons Dideu Industries Group Limited
2-Amino-3-bromo-6-chloropyrazine pictures 2022-02-25 2-Amino-3-bromo-6-chloropyrazine
212779-21-0
 $100.00 1KG 98% 100KG Hong Kong Tiansheng New Material Trading Co., Ltd
3-bromo-6-chloropyrazin-2-amine pictures 2022-02-25 3-bromo-6-chloropyrazin-2-amine
212779-21-0
 $100.00 1KG 98% 10KG Hong Kong Tiansheng New Material Trading Co., Ltd

2-Amino-3-bromo-6-chloropyrazine Spectrum

2-Amino-3-bromo-6-chloropyrazine(212779-21-0)1HNMR

212779-21-0 (2-Amino-3-bromo-6-chloropyrazine) Related Search:

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104365 2-PyrazinaMine, 3-broMo-6-chloro- 3-Bromo-6-chloro-2-pyrazinamine 3-Bromo-6-chloro-pyrazin-2-ylamine 2-Amino-3-bromo-6-chloropyrazine 2-Amino-3-bromo-6-chL 2-Amino-3-bromo-6-chloropyrazine ISO 9001：2015 REACH 212779-21-0