3-BroMo-5-(trifluoroMethyl)anisole
- CAS No.
- 627527-23-5
- Chemical Name:
- 3-BroMo-5-(trifluoroMethyl)anisole
- Synonyms
- 3-Bromo-5-methoxybenzotrifluoride;3-BroMo-5-(trifluoroMethyl)anisole;1-Bromo-3-methoxy-5-trifluoromethylbenzene;Benzene, 1-bromo-3-methoxy-5-(trifluoromethyl)-
- CBNumber:
- CB82502575
- Molecular Formula:
- C8H6BrF3O
- Molecular Weight:
- 255.03
- MDL Number:
- MFCD09999639
- MOL File:
- 627527-23-5.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P280-P301+P312-P362+P364 |
| HS Code | 2909309090 |
3-BroMo-5-(trifluoroMethyl)anisole price More Price(51)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC499010 | 3-Bromo-5-methoxybenzotrifluoride ≥95% | 627527-23-5 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC499010 | 3-Bromo-5-methoxybenzotrifluoride ≥95% | 627527-23-5 | 5g | $55 | 2026-06-04 | Buy |
| Apolloscientific | PC499010 | 3-Bromo-5-methoxybenzotrifluoride ≥95% | 627527-23-5 | 25g | $210 | 2026-06-04 | Buy |
| Activate Scientific | AS39809 | 1-Bromo-3-methoxy-5-(trifluoromethyl)benzene 98% | 627527-23-5 | 1g | $28 | 2026-06-04 | Buy |
| Activate Scientific | AS39809 | 1-Bromo-3-methoxy-5-(trifluoromethyl)benzene 98% | 627527-23-5 | 5g | $79 | 2026-06-04 | Buy |
3-BroMo-5-(trifluoroMethyl)anisole Chemical Properties, Uses, Production
Chemical Properties
light yellow liquid
Synthesis
349-55-3
627527-23-5
1. 3-Methoxy-5-trifluoromethylaniline (20 g, 104.6 mmol) was added batchwise to a cooled solution of sodium nitrite (7.392 g, 107.1 mmol) in sulfuric acid (74 ml) and acetic acid (88 ml). 2. The mixture was added dropwise to a vigorously stirred solution of cuprous bromide (18 g, 62.8 mmol) in 48% hydrobromic acid (200 ml) at 0°C. 3. The reaction mixture was stirred for 45 minutes at room temperature. 4. The reaction mixture was poured into ice water and the aqueous phase was extracted with dichloromethane. 5. The organic layer was separated. (200 ml) solution. 3. The reaction mixture was stirred at room temperature for 45 min. 4. The reaction mixture was poured into ice water and the aqueous phase was extracted with dichloromethane. 5. The organic layer was separated, dried with anhydrous magnesium sulfate, filtered and the solvent was evaporated at low temperature. 6. The residue was stirred in sodium bicarbonate solution and extracted with diisopropyl ether. 7. The organic layer was separated, dried with anhydrous magnesium sulfate, filtered and the solvent was evaporated to obtain intermediate 3-bromo-5-bromo-5-hydroxybromide. 8. The intermediate 3-bromo-5-trifluoromethyl anisole was obtained (12.7 g, 48% yield).
References
[1] Patent: WO2011/33018, 2011, A1. Location in patent: Page/Page column 38
[2] Patent: US2012/172354, 2012, A1. Location in patent: Page/Page column 17
3-BroMo-5-(trifluoroMethyl)anisole Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shijiazhuang Sdyano Fine Chemical Co., Ltd. | 0311-89250318 13582355795 | master@sjzsdyn.com | China | 2776 | 65 |
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Sphchem Co., Ltd. | 021-56491756 13512199871 | 2819742715@qq.com | China | 3994 | 55 |
| Aloespharm Co., Ltd. | 021-20960837 | market@aloespharm.com | China | 1299 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai ACT chemical Limited | 021-59904146 18001826933 | sales@actchemical.com | China | 476 | 56 |
| Nanjing Duolong Bio-tech Co.,Ltd. | 18905173768 | 52513593@qq.com | China | 2337 | 50 |
| Changzhou Tianrui Pharmaceutical Technology Co., Ltd. | 0519-85386832 13382812559 | sales@cztrchem.com | China | 1211 | 56 |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 8455 | 58 |
View Latest Price from 3-BroMo-5-(trifluoroMethyl)anisole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-01-15 | 1-Bromo-3-methoxy-5-(trifluoromethyl)benzene
627527-23-5
|
1KG | 97.7% | 100 tons | Honest Joy Holdings Limited | ||
 |
2020-01-13 | 3-BroMo-5-(trifluoroMethyl)anisole
627527-23-5
|
$1.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- 1-Bromo-3-methoxy-5-(trifluoromethyl)benzene
627527-23-5
- $0.00
- 97.7%
- Honest Joy Holdings Limited
-
- 3-BroMo-5-(trifluoroMethyl)anisole
627527-23-5
- $1.00
- 99%
- Career Henan Chemical Co
