1H-Indole-2-carboxylic acid, 4-Methyl-, ethyl ester
- CAS No.
- 16732-80-2
- Chemical Name:
- 1H-Indole-2-carboxylic acid, 4-Methyl-, ethyl ester
- Synonyms
- Ethyl 4-Methyl-1H-indole-2-carboxylate;4-methyl-1H-indole-2-carboxylic acid ethyl ester;4-Methylindole-2-carboxylic acid ethyl ester, 98%;1H-Indole-2-carboxylic acid, 4-Methyl-, ethyl ester
- CBNumber:
- CB82609452
- Molecular Formula:
- C12H13NO2
- Molecular Weight:
- 203.24
- MDL Number:
- MFCD00981705
- MOL File:
- 16732-80-2.mol
- MSDS File:
- SDS
| Melting point | 140-141 °C |
|---|---|
| Boiling point | 355.6±22.0 °C(Predicted) |
| Density | 1.177±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 15.37±0.30(Predicted) |
| Appearance | White to light yellow Solid |
| InChI | InChI=1S/C12H13NO2/c1-3-15-12(14)11-7-9-8(2)5-4-6-10(9)13-11/h4-7,13H,3H2,1-2H3 |
| InChIKey | ZUJVXCIAKURESZ-UHFFFAOYSA-N |
| SMILES | N1C2=C(C(C)=CC=C2)C=C1C(OCC)=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
1H-Indole-2-carboxylic acid, 4-Methyl-, ethyl ester price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | E55815 | Ethyl 4-methyl-1H-indole-2-carboxylate 97% | 16732-80-2 | 100mg | $43 | 2026-05-06 | Buy |
| Synthonix | E55815 | Ethyl 4-methyl-1H-indole-2-carboxylate 97% | 16732-80-2 | 250mg | $48 | 2026-05-06 | Buy |
| Synthonix | E55815 | Ethyl 4-methyl-1H-indole-2-carboxylate 97% | 16732-80-2 | 1g | $50 | 2026-05-06 | Buy |
| Synthonix | E55815 | Ethyl 4-methyl-1H-indole-2-carboxylate 97% | 16732-80-2 | 5g | $190 | 2026-05-06 | Buy |
| Synthonix | E55815 | Ethyl 4-methyl-1H-indole-2-carboxylate 97% | 16732-80-2 | 10g | $720 | 2026-05-06 | Buy |
1H-Indole-2-carboxylic acid, 4-Methyl-, ethyl ester Chemical Properties, Uses, Production
Synthesis
24512-97-8
16732-80-2
The general procedure for the synthesis of ethyl 4-methyl-1hydro-indole-2-carboxylate from the compound (CAS: 24512-97-8) was as follows: 19.5 g (0.0844 mol) of the azide prepared in step 1 was added in batches to 100 mL of xylene preheated to 140 °C. After the addition was completed, the reaction mixture was kept at 140 °C for 1 hour. At the end of the reaction, the xylene was removed by concentration via reduced pressure distillation, and the residue was dissolved in isopropyl ether, filtered, and dried under vacuum at 40 °C for 18 h to give a white crystalline product. The melting point of the product was 141 °C and the yield was 62%.
References
[1] Journal of the Chemical Society, Chemical Communications, 1982, # 1, p. 3 - 4
[2] Patent: US2004/43995, 2004, A1. Location in patent: Page 13
1H-Indole-2-carboxylic acid, 4-Methyl-, ethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
1H-Indole-2-carboxylic acid, 4-Methyl-, ethyl ester Suppliers
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