ChemicalBook >> CAS DataBase List >>OC000459
OC000459
- CAS No.
- 851723-84-7
- Chemical Name:
- OC000459
- Synonyms
- OC-459;1H-Indole-1-acetic acid, 5-fluoro-2-methyl-3-(2-quinolinylmethyl)-;CS-581;OC000459;OC000495;OC000459, >=98%;OC000459 USP/EP/BP;OC000459(Timapiprant);Timapiprant (OC000459);Timapiprant, 10 mM in DMSO
- CBNumber:
- CB82620011
- Molecular Formula:
- C21H17FN2O2
- Molecular Weight:
- 348.37
- MDL Number:
- MFCD18633254
- MOL File:
- 851723-84-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 05:35:34
| Product description | Number | Pack Size | Price |
| OC000459 ≥98% | 12027 | 5mg | $75 |
| OC000459 ≥98% | 12027 | 10mg | $128 |
| OC000459 ≥98% | 12027 | 25mg | $259 |
| 2-[5-Fluoro-2-methyl-3-(quinolin-2-ylmethyl)-1H-indol-1-yl]acetic acid Asreported | 276619 | 100mg | $701 |
| 2-[5-Fluoro-2-methyl-3-(quinolin-2-ylmethyl)-1H-indol-1-yl]acetic acid Asreported | 276619 | 250mg | $1027 |
| More product size | |||
| Boiling point | 574.4±50.0 °C(Predicted) |
|---|---|
| Density | 1.29 |
| storage temp. | Store at -20°C |
| solubility | DMF: 0.5 mg/ml; DMSO: 1.1 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml |
| form | A crystalline solid |
| pka | 4.08±0.10(Predicted) |
| color | Light yellow to yellow |
| FDA UNII | 04XB9TB8OL |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H303-H320 |
| Precautionary statements | P312-P264-P305+P351+P338-P337+P313 |
OC000459 price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 12027 | OC000459 ≥98% | 851723-84-7 | 5mg | $75 | 2026-04-30 | Buy |
| Cayman Chemical | 12027 | OC000459 ≥98% | 851723-84-7 | 10mg | $128 | 2026-04-30 | Buy |
| Cayman Chemical | 12027 | OC000459 ≥98% | 851723-84-7 | 25mg | $259 | 2026-04-30 | Buy |
| Usbiological | 276619 | 2-[5-Fluoro-2-methyl-3-(quinolin-2-ylmethyl)-1H-indol-1-yl]acetic acid Asreported | 851723-84-7 | 100mg | $701 | 2026-06-03 | Buy |
| Usbiological | 276619 | 2-[5-Fluoro-2-methyl-3-(quinolin-2-ylmethyl)-1H-indol-1-yl]acetic acid Asreported | 851723-84-7 | 250mg | $1027 | 2026-06-03 | Buy |
OC000459 Chemical Properties,Uses,Production
Uses
OC000459 is a CRTH2 antagonist which helps in the treatment of allergies, reducing nasal and ocular symptoms in subjects exposed to allergens.
in vivo
Timapiprant (OC000459) (gavage; 2 mg/kg, 10 mg/kg) inhibits blood eosinophilia induced by 13,14-dihydro-15-keto-PGD2 (DK-PGD2) in Rat (ED50=0.04 mg/kg)[1]. Timapiprant (OC000459) (gavage; 0.01 mg/kg, 0.1 mg/kg, 1.0 mg/kg) inhibits airway eosinophilia in response to an aerosol of DK-PGD2 in guinea pigs (ED50=0.01 mg/kg)[1].
IC 50
DP
OC000459 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 146)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Dideu Industries Group Limited | +8617392712697 | 1022@dideu.com | China | 29095 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10378 | 58 |
| Guangzhou TongYi biochemistry technology Co.,LTD | tongyibiochem@163.com | China | 2988 | 58 | |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +8619957148339 | market18@leapchem.com | China | 24569 | 58 |
| Dingwang Technology (Wuhan) Co., Ltd. | +undefined-27-2786652399 +undefined13627115097 | market02@senwayer.com | China | 886 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +86-15965530500 | nickzhang@hangyubiotech.com | China | 9932 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20111 | 58 |
View Lastest Price from OC000459 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-30 | OC000459
851723-84-7
|
1KG | 98 | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-08-22 | OC000459
851723-84-7
|
100mg | 99% | 50-100kg | Dingwang Technology (Wuhan) Co., Ltd. | ||
 |
2024-11-01 | OC000459
851723-84-7
|
1g | 98%+ | 100kgs | Wuhan Nutra Biotechnology Co.,Ltd |
851723-84-7(OC000459)Related Search:
OC000459
2-(5-fluoro-2-Methyl-3-(quinolin-
2-ylMethyl)-1H-indol-1-yl)acetic
acid
5-Fluoro-2-Methyl-3-quinolin-2-ylMethylindo-1-yl)-acetic(OC000459)
[5-Fluoro-2-methyl-3-(quinolin-2-ylmethyl)indol-1-yl]acetic acid
5-Fluoro-2-methyl-3-(2-quinolinylmethyl)-1H-indole-1-acetic acid
OC000495
(5-Fluoro-3-isoquinolin-3-ylMethyl-2-Methyl-indol-1-yl)-acetic acid
1H-Indole-1-acetic acid, 5-fluoro-2-methyl-3-(2-quinolinylmethyl)-
[5-Fluoro-2-methyl-3-(quinolin-2-ylmethyl)indol-1-yl]acetic acid OC000459
OC000459;OC-000459; OC 000459
OC000459, >=98%
CS-581
OC000459(Timapiprant)
2-[5-FLUORO-2-METHYL-3-(QUINOLIN-2-YLMETHYL)INDOL-1-YL]ACETIC ACID
OC000459 USP/EP/BP
Timapiprant (OC000459)
Timapiprant, 10 mM in DMSO
[5-Fluoro-2-methyl-3-(2-quinolinylmethyl)-1H-indol-1-yl]acetic acid
OC-459
851723-84-7
51723-84-7
Inhibitors
