4-Chloro-2-iodo-6-nitro-phenylaMine
- CAS No.
- 123158-75-8
- Chemical Name:
- 4-Chloro-2-iodo-6-nitro-phenylaMine
- Synonyms
- 4-Chloro-2-iodo-6-nitroaniline;Medetomidine Impurity 66;4-Chloro-2-iodo-6-nitro-phenylaMine;Benzenamine, 4-chloro-2-iodo-6-nitro-
- CBNumber:
- CB82641276
- Molecular Formula:
- C6H4ClIN2O2
- Molecular Weight:
- 298.47
- MDL Number:
- MFCD23115369
- MOL File:
- 123158-75-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 |
4-Chloro-2-iodo-6-nitro-phenylaMine price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS115513 | 4-Chloro-2-iodo-6-nitroaniline 95% | 123158-75-8 | 1g | $117 | 2026-06-04 | Buy |
| Activate Scientific | AS115513 | 4-Chloro-2-iodo-6-nitroaniline 95% | 123158-75-8 | 5g | $419 | 2026-06-04 | Buy |
| Matrix Scientific | 293520 | 4-Chloro-2-iodo-6-nitroaniline | 123158-75-8 | 250.00mg | $46 | 2026-05-19 | Buy |
| Matrix Scientific | 293520 | 4-Chloro-2-iodo-6-nitroaniline | 123158-75-8 | 1.00g | $102 | 2026-05-19 | Buy |
| Matrix Scientific | 293520 | 4-Chloro-2-iodo-6-nitroaniline | 123158-75-8 | 5.00g | $342 | 2026-05-19 | Buy |
4-Chloro-2-iodo-6-nitro-phenylaMine Chemical Properties, Uses, Production
Synthesis
89-63-4
123158-75-8
A. Synthesis of 4-chloro-2-iodo-6-nitroaniline: adapted from the method of Leeson, P.D. et al. (J. Med. Chem. 34:1243-1252 (1991)). 4-Chloro-2-nitroaniline (2.15 g, 12.45 mmol, Aldrich, direct use) was dissolved in glacial acetic acid (16 mL) followed by iodine monochloride (2.114 g, 12.90 mmol, Aldrich). The reaction mixture was heated at 120 °C for 5 h. After completion of the reaction, it was cooled to room temperature and poured into ice water (30 g). The precipitate was collected by filtration, washed with 10% sodium sulfite solution (20 mL), and finally recrystallized by methanol to give 4-chloro-2-iodo-6-nitroaniline (1.05 g, 28% yield) as long brown needle-like crystals with a melting point of 205 °C (literature values 134-135 °C). The NMR hydrogen spectrum (1H, CDCl3) data were as follows: δ 6.660 (s, 2H); 7.906 (d, 1H, J = 2.1 Hz); 8.188 (d, 1H, J = 1.8 Hz).
References
[1] Chemistry - A European Journal, 2003, vol. 9, # 21, p. 5323 - 5331
[2] Patent: US2010/291533, 2010, A1. Location in patent: Page/Page column 57
[3] Journal of Medicinal Chemistry, 1991, vol. 34, # 4, p. 1243 - 1252
[4] Patent: US5514680, 1996, A
[5] Journal of the Chemical Society, 1928, p. 783
4-Chloro-2-iodo-6-nitro-phenylaMine Preparation Products And Raw materials
4-Chloro-2-iodo-6-nitro-phenylaMine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SuZhou ShiYa Biopharmaceuticals, Inc. | 86(512)5235 8471 17715136450 | sales@shiyabiopharm.com | China | 4167 | 58 |
| Shanghai Uchem Inc. | 15618758386 15618758386 | sales3@myuchem.com | China | 1994 | 55 |
| Shanghai SuperLan Chemcial Technique Centre | 0-2022843681 15618226720 | chaolaichem@foxmail.com | China | 9996 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Sichuan BoYou Biotechnology Co., Ltd. | 028-65791793 18140026355 | 568470422@qq.com | China | 9961 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Henan's chemical products co., LTD | 0371-60919097 15378766539; | 794449696@qq.com | China | 5000 | 58 |
| Changzhou Yinghao Technology Development Co., Ltd | 15151934985 | sales@yingsapharm.com | China | 5452 | 58 |
| Zhengzhou Alpha Chemical Co. LTD | 0371-53732842 13383863444 | 3838551451@qq.com | China | 9996 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
