1-tert-butyl azepane-1,4-dicarboxylate 4-ethyl ester
- CAS No.
- 912444-90-7
- Chemical Name:
- 1-tert-butyl azepane-1,4-dicarboxylate 4-ethyl ester
- Synonyms
- 1-Boc-azepane-4-carboxylic acid ethyl ester;1-tert-Butyl 4-ethyl azepane-1,4-dicarboxylate;1-O-tert-butyl 4-O-ethyl azepane-1,4-dicarboxylate;1-tert-butyl azepane-1,4-dicarboxylate 4-ethyl ester;1H-Azepine-1,4-dicarboxylic acid, hexahydro-, 1-(1,1-diMethylethyl) 4-ethyl ester
- CBNumber:
- CB82642819
- Molecular Formula:
- C14H25NO4
- Molecular Weight:
- 271.35
- MDL Number:
- MFCD18088889
- MOL File:
- 912444-90-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
1-tert-butyl azepane-1,4-dicarboxylate 4-ethyl ester price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 301331 | 1-tert-Butyl 4-ethyl azepane-1,4-dicarboxylate | 912444-90-7 | 250.00mg | $54 | 2026-05-19 | Buy |
| Matrix Scientific | 301331 | 1-tert-Butyl 4-ethyl azepane-1,4-dicarboxylate | 912444-90-7 | 1.00g | $191 | 2026-05-19 | Buy |
| Matrix Scientific | 301331 | 1-tert-Butyl 4-ethyl azepane-1,4-dicarboxylate | 912444-90-7 | 5.00g | $720 | 2026-05-19 | Buy |
| aablocks | AA00H0X7 | 1-tert-Butyl 4-ethyl azepane-1,4-dicarboxylate 95% | 912444-90-7 | 100mg | $23 | 2026-05-28 | Buy |
| aablocks | AA00H0X7 | 1-tert-Butyl 4-ethyl azepane-1,4-dicarboxylate 97% | 912444-90-7 | 250mg | $40 | 2026-05-28 | Buy |
1-tert-butyl azepane-1,4-dicarboxylate 4-ethyl ester Chemical Properties, Uses, Production
Synthesis
912444-89-4
912444-90-7
General procedure for the synthesis of ethyl 1-azepane-N-Boc-4-carboxylate from 1-tert-butyl 4-ethyl 1H-azepine-1,4-dicarboxylate from 2,3,6,7-tetrahydro-1H-azepine-1,4-dicarboxylic acid: 1-tert-butyl 4-ethyl azepine-1,4-dicarboxylate (0.54 g, 2.0 mmol) was dissolved in 20 ml of methanol, 10% Pd/C (50 mg) was added , and the reaction was carried out overnight under hydrogen atmosphere. After completion of the reaction, the solid catalyst was removed by filtration and the filtrate was concentrated. The resulting residue was purified by fast column chromatography (eluent: hexane solution of 20% ethyl acetate) to afford the target product ethyl 1-azepane-N-Boc-4-carboxylate (310 mg, 55% yield). The mass spectrum (DCI/NH3) showed m/z 272 (M+H)+.
References
[1] Patent: US2006/229289, 2006, A1. Location in patent: Page/Page column 22-23
1-tert-butyl azepane-1,4-dicarboxylate 4-ethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Shanghai Synmedia Chemical Co., Ltd. | 021-38681880 13817889927 | sales@synmedia-chem.com | China | 249 | 58 |
| GIHI CHEMICALS CO.,LTD | 0086-571-86217390 | Sales@gihichem.com | China | 858 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Aikon International Limited | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 15810 | 58 |
| Yujinpharma(Tianjin) Technology Co.,Ltd. | 13370351217 kungfu1217@1 | kungfu1217@163.com | China | 7991 | 58 |
| Shanghai SPAR pharmaceutical technology co., LTD | 021-000000 | admin@jingshipharmatech.com | China | 9919 | 58 |
| Cool Pharm, Ltd | 021-58581007 18019463053 | sales@coolpharm.com | China | 9999 | 58 |
| Shanghai FWD Chemicals Limited | 021-544580828 021-54450828 | sales@fwdchem.com | China | 996 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
