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6-Amino-2,4-dimethyl-3-pyridinecarbonitrile

6-Amino-2,4-dimethyl-3-pyridinecarbonitrile Structure
6-Amino-2,4-dimethyl-3-pyridinecarbonitrile structure
CAS No.
769-27-7
Chemical Name:
6-Amino-2,4-dimethyl-3-pyridinecarbonitrile
Synonyms
6-amino-2,4-dimethyL;6-amino-2,4-dimethylpyridine-3-carbonitrile;6-Amino-2,4-dimethyl-3-pyridinecarbonitrile;3-Pyridinecarbonitrile, 6-amino-2,4-dimethyl-
CBNumber:
CB82665290
Molecular Formula:
C8H9N3
Molecular Weight:
147.18
MDL Number:
MFCD00027370
MOL File:
769-27-7.mol
MSDS File:
SDS
Last updated:2026-09-12 18:55:37
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6-Amino-2,4-dimethyl-3-pyridinecarbonitrile Properties

Melting point 230 °C
Boiling point 314.5±42.0 °C(Predicted)
Density 1.14±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 4.30±0.48(Predicted)
Appearance Off-white to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Skull and Crossbones (GHS06)
GHS05,GHS06
Signal word  Danger
Hazard statements  H301-H315-H318-H335
Precautionary statements  P261-P280-P301+P310-P305+P351+P338

6-Amino-2,4-dimethyl-3-pyridinecarbonitrile price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S461237 6-AMINO-2,4-DIMETHYL-3-PYRIDINECARBONITRILE AldrichCPR 769-27-7 1 unit $197 2026-04-30 Buy
Sigma-Aldrich S461237 6-AMINO-2,4-DIMETHYL-3-PYRIDINECARBONITRILE Aldrich 769-27-7 250mg $179 2024-03-01 Buy
Synthonix A49205 6-Amino-2,4-dimethylnicotinonitrile 95+% 769-27-7 250mg $70 2026-05-06 Buy
Synthonix A49205 6-Amino-2,4-dimethylnicotinonitrile 95+% 769-27-7 1g $77 2026-05-06 Buy
Synthonix A49205 6-Amino-2,4-dimethylnicotinonitrile 95+% 769-27-7 5g $80 2026-05-06 Buy
Product number Packaging Price Buy
S461237 1 unit $197 Buy
S461237 250mg $179 Buy
A49205 250mg $70 Buy
A49205 1g $77 Buy
A49205 5g $80 Buy

6-Amino-2,4-dimethyl-3-pyridinecarbonitrile Chemical Properties, Uses, Production

Synthesis

ZINC CYANIDE

557-21-1

2-AMINO-4,6-DIMETHYL-5-IODOPYRIDINE

885952-12-5

6-AMINO-2,4-DIMETHYL-3-PYRIDINECARBONITRILE

769-27-7

To a solution of 5-iodo-4,6-dimethylpyridin-2-amine (10 g, 40.3 mmol, 1.0 eq.) in N,N-dimethylformamide (DMF, 300 mL) was sequentially added zinc cyanide (Zn(CN)2, 14 g, 120.9 mmol, 3.0 eq.) and tetrakis(triphenylphosphine)palladium (Pd(PPh3)4, 4.65 g, 4.03 mmol, 0.1 equiv). The reaction mixture was stirred at 90 °C under nitrogen (N2) protection overnight. After completion of the reaction, extraction was carried out by adding ethyl acetate (EA) and water. The organic layer was separated and concentrated under reduced pressure. The resulting residue was purified by silica gel column chromatography (eluent: dichloromethane/methanol=100/1, v/v) to afford 6-amino-2,4-dimethyl-3-cyanopyridine (5 g, 84% yield) as a yellow solid.

References

[1] Patent: WO2017/1926, 2017, A2. Location in patent: Paragraph 00123

6-Amino-2,4-dimethyl-3-pyridinecarbonitrile Preparation Products And Raw materials

Raw materials

(E)-3-Amino-2-butenenitrile ZINC CYANIDE 2-Amino-4,6-dimethyl-5-iodopyridine Tetrakis(triphenylphosphine)palladium N,N-Dimethylformamide

Preparation Products

6-Amino-2,4-dimethyl-3-pyridinecarbonitrile Suppliers

Global Suppliers ( 32)
Supplier Tel Email Country ProdList Advantage
Shanghai XIYU Chemical Technology Co.,Ltd. 021-15000143735 15221126179 sala@xiyuchem.com China 375 55
Shanghai Xingui Biotechnology Co., Ltd. 15121041756 xingui2022@126.com China 9961 58
ShangHai Wisacheam Pharmaceutical Co., Ltd. 13817485796 tim@wisacheampharm.com China 3700 58
Shanghai Universe International trade Co.,Ltd 17317567081 info@coreuni.com China 201 55
Shanghai Sainty Biotechnology Co., Ltd. 021-58957915 17721108391 907522080@qq.com China 997 55
ShangHai Angti Biotechnology Co., Ltd. 13764913901 info@angtibio.com China 4975 55
Wuxi AppTec 022-59987777 13552403979 jia_guoqiang@wuxiapptec.com China 22344 58
Huaian Hyperion pharmaceutical R&D Co.,Ltd. 18114966287 sales@hyperionpharm.com China 456 58
Aikon International Limited 025-66061636 19370895928 qqyang@aikonchem.com China 15810 58
3A Chemicals 400-668-9898 service@3achem.com China 20535 58
Supplier Advantage
Shanghai XIYU Chemical Technology Co.,Ltd. 55
Shanghai Xingui Biotechnology Co., Ltd. 58
ShangHai Wisacheam Pharmaceutical Co., Ltd. 58
Shanghai Universe International trade Co.,Ltd 55
Shanghai Sainty Biotechnology Co., Ltd. 55
ShangHai Angti Biotechnology Co., Ltd. 55
Wuxi AppTec 58
Huaian Hyperion pharmaceutical R&D Co.,Ltd. 58
Aikon International Limited 58
3A Chemicals 58

6-Amino-2,4-dimethyl-3-pyridinecarbonitrile Spectrum

6-AMINO-2,4-DIMETHYL-3-PYRIDINECARBONITRILE(769-27-7)MS6-AMINO-2,4-DIMETHYL-3-PYRIDINECARBONITRILE(769-27-7)1HNMR6-AMINO-2,4-DIMETHYL-3-PYRIDINECARBONITRILE(769-27-7)IR16-AMINO-2,4-DIMETHYL-3-PYRIDINECARBONITRILE(769-27-7)IR2

769-27-7 (6-Amino-2,4-dimethyl-3-pyridinecarbonitrile) Related Search:

6-Amino-2-methylnicotinonitrile 2-Amino-5-cyano-4-picoline Carbamic acid, N-(5-cyano-4,6-dimethyl-2-pyridinyl)-, 1,1-dimethylethyl ester 3-Pyridinecarboxylic acid, 6-amino-2,4-dimethyl- 3-Pyridinecarboxaldehyde, 6-amino-2,4-dimethyl- (9CI)
2-Amino-3-cyano-4,6-dimethylpyridine

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6-amino-2,4-dimethylpyridine-3-carbonitrile 6-amino-2,4-dimethyL 3-Pyridinecarbonitrile, 6-amino-2,4-dimethyl- 6-Amino-2,4-dimethyl-3-pyridinecarbonitrile 769-27-7