(Z)-Methyl 2-(hydroxyiMino)-2-(pyridin-2-yl)acetate
- CAS No.
- 154410-82-9
- Chemical Name:
- (Z)-Methyl 2-(hydroxyiMino)-2-(pyridin-2-yl)acetate
- Synonyms
- Methyl 2-(hydroxyimino)-2-(pyridin-2-yl)acetate;methyl 2-(N-hydroxyimino)-2-(pyridin-2-yl)acetate;ethyl (Z)-2-(hydroxyimino)-2-(pyridin-2-yl)acetate;(Z)-ethyl 2-(hydroxyimino)-2-(pyridin-2-yl)acetate;(Z)-Methyl 2-(hydroxyiMino)-2-(pyridin-2-yl)acetate;Methyl (Z)-2-(hydroxyimino)-2-(pyridin-2-yl)acetate;methyl (2Z)-2-nitroso-2-(1H-pyridin-2-ylidene)acetate;2-Pyridineacetic acid, α-(hydroxyimino)-, methyl ester
- CBNumber:
- CB82666545
- Molecular Formula:
- C8H8N2O3
- Molecular Weight:
- 180.16
- MDL Number:
- MFCD27966261
- MOL File:
- 154410-82-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| (Z)-Methyl2-(Hydroxyimino)-2-(pyridin-2-yl)acetate | M593000 | 10mg | $45 |
| (Z)-Methyl2-(hydroxyimino)-2-(pyridin-2-yl)acetate 97% | CD11248245 | 250mg | $95 |
| (Z)-Methyl2-(hydroxyimino)-2-(pyridin-2-yl)acetate 95% | CM244504 | 1g | $184 |
| (Z)-Methyl2-(hydroxyimino)-2-(pyridin-2-yl)acetate 97% | CD11248245 | 1g | $238 |
| (Z)-Methyl2-(hydroxyimino)-2-(pyridin-2-yl)acetate 95% | CM244504 | 5g | $514 |
| More product size | |||
(Z)-Methyl 2-(hydroxyiMino)-2-(pyridin-2-yl)acetate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M593000 | (Z)-Methyl2-(Hydroxyimino)-2-(pyridin-2-yl)acetate | 154410-82-9 | 10mg | $45 | 2021-12-16 | Buy |
| Crysdot | CD11248245 | (Z)-Methyl2-(hydroxyimino)-2-(pyridin-2-yl)acetate 97% | 154410-82-9 | 250mg | $95 | 2021-12-16 | Buy |
| Chemenu | CM244504 | (Z)-Methyl2-(hydroxyimino)-2-(pyridin-2-yl)acetate 95% | 154410-82-9 | 1g | $184 | 2021-12-16 | Buy |
| Crysdot | CD11248245 | (Z)-Methyl2-(hydroxyimino)-2-(pyridin-2-yl)acetate 97% | 154410-82-9 | 1g | $238 | 2021-12-16 | Buy |
| Chemenu | CM244504 | (Z)-Methyl2-(hydroxyimino)-2-(pyridin-2-yl)acetate 95% | 154410-82-9 | 5g | $514 | 2021-12-16 | Buy |
(Z)-Methyl 2-(hydroxyiMino)-2-(pyridin-2-yl)acetate Chemical Properties,Uses,Production
Synthesis
1658-42-0
154410-82-9
The general procedure for the synthesis of methyl 2-(oxime)-2-(pyridin-2-yl)acetate from methyl 2-pyridylacetate was as follows: to a stirring solution of methyl 2-pyridylacetate (8.9 mL, 0.66 mmol) in acetic acid (16 mL) at 0 °C, an aqueous sodium nitrite solution (4.67 g, 0.66 mmol, 14 mL) was slowly added. After addition, the reaction mixture was continued to be stirred at room temperature for 40 min. Subsequently, water (30 mL) was added and the mixture was stirred for another 1 hour. Upon completion of the reaction, the mixture was concentrated to remove most of the acetic acid and alkalized with aqueous sodium carbonate to pH 8-9. The aqueous phase was extracted with ethyl acetate (3×). The organic phases were combined, dried with magnesium sulfate, filtered, and concentrated under vacuum. Finally, the product was dried in a vacuum oven to afford methyl 2-(oxime)-2-(pyridin-2-yl)acetate (11.6 g, 97% yield) as an off-white solid with a mass spectrum m/z 181.6 [M + 1]+.
References
[1] Patent: WO2009/70485, 2009, A1. Location in patent: Page/Page column 131
[2] Journal of Heterocyclic Chemistry, 1993, vol. 30, # 5, p. 1253 - 1260
[3] Zhurnal Obshchei Khimii, 1935, vol. 5, p. 1699,1703
[4] Chem. Zentralbl., 1935, vol. 106, # II, p. 3240
[5] Journal of Medicinal Chemistry, 2013, vol. 56, # 20, p. 8049 - 8065
(Z)-Methyl 2-(hydroxyiMino)-2-(pyridin-2-yl)acetate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Golden Pharma Co., Limited | +undefined18958062155 | sales@zjgoldpharm.com | China | 5899 | 58 |
| Beijing Eternalchem Co,. Ltd. | 010-59484199 18611897322 | sales@eternalchem.com | China | 4383 | 60 |
| CEG Chemical Science&Technology Co., Ltd. | Mobile:13665161512 | China | 1785 | 58 | |
| Shanghai HuanChuan Industry Co.,Ltd. | 021-61478794 | sales@hcshhai.com | China | 9793 | 50 |
| AN PharmaTech Co Ltd | 86(21)68097365 | sales@anpharma.net | China | 4891 | 55 |
| ShangHai Angti Biotechnology Co., Ltd. | 13764913901 | info@angtibio.com | China | 4986 | 55 |
| BePharm Ltd | 400-685-9117 | market@bepharm.com | China | 15081 | 60 |
| NanJing Xienuo bio Co.,Ltd. | 025-84112752 13805181430 | 154301870@qq.com | China | 1000 | 55 |
| Suzhou Nuoouman Biological Technology Co., Ltd. | 15026866316 | 180642609@qq.com | China | 4967 | 58 |
