PHA-767491 (hydrochloride)
- CAS No.
- 942425-68-5
- Chemical Name:
- PHA-767491 (hydrochloride)
- Synonyms
- PHA-767491 HCl ，S2742;CAY-10572 HYDROCHLORIDE;PHA-767491A hydrochloride;PHA-767491 hydrochloride, 10 mM in DMSO;CAY10572 (PHA-767491), Cdc7 and Cdk9 kinase inhibitor;2-(Pyridin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride
- CBNumber:
- CB82735533
- Molecular Formula:
- C12H12ClN3O
- Molecular Weight:
- 249.7
- MDL Number:
- MOL File:
- 942425-68-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
PHA-767491 (hydrochloride) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 18218 | PHA-767491 (hydrochloride) ≥98% | 942425-68-5 | 5mg | $53 | 2026-04-30 | Buy |
| Cayman Chemical | 18218 | PHA-767491 (hydrochloride) ≥98% | 942425-68-5 | 10mg | $94 | 2026-04-30 | Buy |
| Cayman Chemical | 18218 | PHA-767491 (hydrochloride) ≥98% | 942425-68-5 | 25mg | $205 | 2026-04-30 | Buy |
| Cayman Chemical | 18218 | PHA-767491 (hydrochloride) ≥98% | 942425-68-5 | 50mg | $357 | 2026-04-30 | Buy |
| Usbiological | 256228 | PHA 767491 hydrochloride Asreported | 942425-68-5 | 10mg | $403 | 2026-06-03 | Buy |
PHA-767491 (hydrochloride) Chemical Properties, Uses, Production
Uses
PHA 767491 Hydrochloride (cas# 942425-68-5) is a useful research chemical used in the synthesis of heteroaryl-substituted pyrrolopyridinones and analogs as cdc7 kinase inhibitors and potential antitumor agents.
in vivo
PHA-767491 decreases Chk1 phosphorylation and increases in situ cell apoptosis in tumor tissues sectioned from nude mice HCC xenografts[2].
IC 50
CDK9: 34 nM (IC50); CDK2: 240 nM (IC50); CDK1: 250 nM (IC50); CDK5: 460 nM (IC50); GSK3-β: 220 nM (IC50); Mk2: 470 nM (IC50); Plk1: 980 nM (IC50); Chk2: 1100 nM (IC50)
storage
Desiccate at RT
PHA-767491 (hydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7545 | 61 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4853 | 58 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
| ShangHai Siyan Biological Technology Co., Ltd. | 021-50908862，442785678，326799392 18721037013 | siyansales@126.com | China | 9612 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Guangzhou QiYun Biotechnology Co., Ltd. | 020-61288194 61288195 | 505721671@qq.com | China | 3853 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 9780 | 55 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
View Latest Price from PHA-767491 (hydrochloride) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | PHA-767491 hydrochloride
942425-68-5
|
$43.00-98.00 | 99.80% | 10g | TargetMol Chemicals Inc. |
-
- PHA-767491 hydrochloride
942425-68-5
- $43.00-98.00
- 99.80%
- TargetMol Chemicals Inc.
