COENZYME Q1
- CAS No.
- 727-81-1
- Chemical Name:
- COENZYME Q1
- Synonyms
- Nsc 268269;COENZYME Q1;UBIQUINONE-5;Ubiquinone 1;Ubiquinone Q1;Coenzyme?Q1;Coenzyme Q1(solution in ethanol);2-Isopentenyl-5,6-dimethoxy-3-methyl-p-benzoquinone;2,3-DIMETHOXY-5-METHYL-6-(3-METHYL-2-BUTENYL)-1,4-BENZOQUINONE;2,3-dimethoxy-5-methyl-6-(3-methylbut-2-enyl)cyclohexa-2,5-diene-1,4-dione
- CBNumber:
- CB8278506
- Molecular Formula:
- C14H18O4
- Molecular Weight:
- 250.29
- MDL Number:
- MFCD00274412
- MOL File:
- 727-81-1.mol
- MSDS File:
- SDS
| Boiling point | 389.1±42.0 °C(Predicted) |
|---|---|
| Density | 1.10±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMF: 10 mg/ml; Ethanol: 10 mg/ml |
| form | Orange-red to red liquid. |
| color | Orange to red |
| FDA UNII | JR17826E4G |
| UNSPSC Code | 12352204 |
| NACRES | NA.51 |
COENZYME Q1 price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C7956 | Coenzyme Q1 ≥95% | 727-81-1 | 2mg | $128 | 2025-07-31 | Buy |
| Sigma-Aldrich | C7956 | Coenzyme Q1 ≥95% | 727-81-1 | 10mg | $385 | 2025-07-31 | Buy |
| Cayman Chemical | 18741 | Coenzyme Q1 ≥98% | 727-81-1 | 1mg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 18741 | Coenzyme Q1 ≥98% | 727-81-1 | 5mg | $190 | 2024-03-01 | Buy |
| Sigma-Aldrich | C7956 | Coenzyme Q1 ≥95% | 727-81-1 | 5x10mg | $1550 | 2025-07-31 | Buy |
COENZYME Q1 Chemical Properties,Uses,Production
Description
Cooenzyme Q10 (CoQ10) is a component of the electron transport chain and participates in aerobic cellular respiration, generating energy in the form of ATP. CoQ1 is an amphipathic CoQ10 homolog that has a tail consisting of five isoprene units. It has been used as an electron acceptor to study a range of oxidoreductases as isolated enzymes, in subcellular fractions, in intact cells in culture, and in perfused organs. Ubiquinone analogs, including CoQ1, impact mitochondrial permeability transition pore (PTP) formation, as well as PTP-dependent cell death, in an analog- and cell-specific manner.
Uses
Coenzyme Q1 has been used to measure the mitochondrial respiratory chain complex 1 activity.
Uses
Coenzyme Q1 is an electron acceptor and a component of the electron transport chain. It also play a role in the?mitochondrial permeability transition pore (PTP). Coenzyme Q1 is structurally similar to?coenzyme Q2 (C636450)?and?coenzyme Q10 (C636501).
Definition
ChEBI: Ubiquinones is any benzoquinone derived from 2,3-dimethoxy-5-methylbenzoquinone; one of a group of naturally occurring homologues. The redox-active quinoid moiety usually carries a polyprenoid side chain at position 6, the number of isoprenoid units in which is species-specific. Ubiquinones are involved in the control of mitochondrial electron transport, and are also potent anti-oxidants. It has a role as an Escherichia coli metabolite and a mouse metabolite. It is a prenylquinone and a member of 1,4-benzoquinones. It is functionally related to a 2,3-dihydroxy-5-methyl-1,4-benzoquinone.
General Description
Coenzyme Q (CoQ) is localized to the hydrophobic domain of the phospholipid bilayer of mitochondria, plasma lipoproteins, and other biological membranes. It is a ubiquinone homolog with a short isoprenoid side chain.
Biochem/physiol Actions
Coenzyme Q1 (CoQ1) is a 1 isoprenyl group (not naturally occurring) member of a family of ubiquinones that share a quinine chemical group but differ in the number of isoprenyl chemical subunits in their tail. The CoQ compounds are lipid soluble components of cell membranes where they perform multiple functions such as electron and proton transport. The most well studied CoQ compound is CoQ10. CoQ1 is frequently used in comparison studies on the effect of isoprenyl chain length on CoQ functions or distribution and to identify quinone reductases.
References
[1] ROMANA FATO. Steady-State Kinetics of the Reduction of Coenzyme Q Analogs by Complex I (NADH:Ubiquinone Oxidoreductase) in Bovine Heart Mitochondria and Submitochondrial Particles?[J]. Biochemistry Biochemistry, 1996, 35 8: 2705-2716. DOI: 10.1021/bi9516034
[2] FLAVIEN DEVUN. Ubiquinone analogs: a mitochondrial permeability transition pore-dependent pathway to selective cell death.[J]. PLoS ONE, 2010: e11792. DOI: 10.1371/journal.pone.0011792
[3] ROBERT D BONGARD. Coenzyme Q(1) as a probe for mitochondrial complex I activity in the intact perfused hyperoxia-exposed wild-type and Nqo1-null mouse lung.[J]. American journal of physiology. Lung cellular and molecular physiology, 2012: L949-58. DOI: 10.1152/ajplung.00251.2011
COENZYME Q1 Preparation Products And Raw materials
Raw materials
Preparation Products
COENZYME Q1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32430 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39030 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53900 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51395 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
| Shenzhen Regent Biochemical Technology Co., Ltd. | 0755-85201366 18938635012 | sales@regentsciences.com | China | 9760 | 58 |
| Rhawn Reagent | 400-400-1332688 18019345275 | amy@rhawn.cn | China | 15497 | 58 |
View Lastest Price from COENZYME Q1 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-08-27 | Ubiquinone-1
727-81-1
|
US $0.00 / removed | 10g | TargetMol Chemicals Inc. |
-
- Ubiquinone-1
727-81-1
- US $0.00 / removed
- TargetMol Chemicals Inc.
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