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1-(1-bromoethyl)-4-fluorobenzene

1-(1-bromoethyl)-4-fluorobenzene Structure
1-(1-bromoethyl)-4-fluorobenzene structure
CAS No.
65130-46-3
Chemical Name:
1-(1-bromoethyl)-4-fluorobenzene
Synonyms
1-(1-Bromoethyl);-4-fluorobenzene;4-FLUOROPHENETHYL BROMIDE;2-(4-FLUOROPHENYL)ETHYL BROMIDE;1-(4-Fluorophenyl)ethyl bromide;1-(1-Bromoethyl)-4-fluorobenzene;1-BROMO-2-(4-FLUOROPHENYL)ETHANE;1-FLUORO-4-(2-BROMOETHYL)BENZENE;4-FLUORO-1-(2-BROMOETHYL)BENZENE;1-Bromo-1-(4-fluorophenyl)ethane
CBNumber:
CB8280260
Molecular Formula:
C8H8BrF
Molecular Weight:
203.05
MDL Number:
MFCD11180274
MOL File:
65130-46-3.mol
MSDS File:
SDS
Last updated:2026-05-28 03:29:02
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1-(1-bromoethyl)-4-fluorobenzene Properties

Boiling point 100-104 °C15 mm Hg(lit.)
Density 1.4498 g/mL at 25 °C(lit.)
refractive index n20/D 1.534(lit.)
Flash point 200 °F
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
form oil
color Colourless

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P280
Hazard Codes  Xn,N
Risk Statements  22-51/53
Safety Statements  61
WGK Germany  2
Hazard Note  Harmful
HS Code  2903998090

1-(1-bromoethyl)-4-fluorobenzene price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC51144 4-Fluoro-alpha-methylbenzyl bromide 95% 65130-46-3 1g $25 2026-06-04 Buy
Apolloscientific PC51144 4-Fluoro-alpha-methylbenzyl bromide 95% 65130-46-3 5g $60 2026-06-04 Buy
Apolloscientific PC51144 4-Fluoro-alpha-methylbenzyl bromide 95% 65130-46-3 10g $113 2026-06-04 Buy
Apolloscientific PC51144 4-Fluoro-alpha-methylbenzyl bromide 95% 65130-46-3 25g $258 2026-06-04 Buy
Apolloscientific PC51144 4-Fluoro-alpha-methylbenzyl bromide 95% 65130-46-3 100g $746 2026-06-04 Buy
Product number Packaging Price Buy
PC51144 1g $25 Buy
PC51144 5g $60 Buy
PC51144 10g $113 Buy
PC51144 25g $258 Buy
PC51144 100g $746 Buy

1-(1-bromoethyl)-4-fluorobenzene Chemical Properties, Uses, Production

Synthesis

1-(4-Fluorophenyl)ethanol

403-41-8

1-(1-bromoethyl)-4-fluorobenzene

65130-46-3

General procedure for the synthesis of 1-(1-bromoethyl)-4-fluorobenzene from 1-(4-fluorophenyl)-1-ethanol: 1-(4-fluorophenyl)ethanol (0.455 mL, 3.57 mmol) was mixed with phosphorus tribromide (0.673 mL, 7.13 mmol) in chloroform (10 mL) and heated to a temperature of 70°C for 3 days. Upon completion of the reaction, the reaction mixture was quenched by pouring it into ice water and diluted with ethyl acetate. The organic layer was separated, washed sequentially with water and brine, dried over anhydrous sodium sulfate and concentrated in vacuum to obtain the crude product. The crude product was purified by silica gel column chromatography with hexane/dichloromethane (2:1) as eluent to afford 1-(1-bromoethyl)-4-fluorobenzene (154 mg, 0.758 mmol, 21.3% yield) as a colorless oil.1H NMR (400 MHz, CDCl3) δ 7.49-7.40 (m, 2H), 7.09-7.00 (m , 2H), 5.23 (q, J = 7.0 Hz, 1H), 2.06 (d, J = 6.8 Hz, 3H).

References

[1] Journal of the American Chemical Society, 2016, vol. 138, # 34, p. 10774 - 10777
[2] Patent: US2012/46301, 2012, A1. Location in patent: Page/Page column 30; 31
[3] Patent: WO2018/148626, 2018, A1. Location in patent: Page/Page column 152
[4] Tetrahedron, 1977, vol. 33, p. 1581 - 1585
[5] Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical & Analytical, 1984, vol. 23, # 1, p. 60 - 62

1-(1-bromoethyl)-4-fluorobenzene Preparation Products And Raw materials

Raw materials

1-(4-Fluorophenyl)ethanol 1-Ethyl-4-fluorobenzene 3-Bromo-alpha-methylbenzyl alcohol Phosphorus tribromide Chloroform

Preparation Products

1-(1-bromoethyl)-4-fluorobenzene Suppliers

Global Suppliers ( 72)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Cochemical Ltd. 029-86115547 17791676824 sales@cochemical.com China 3014 58
Shanghai Worldyang Chemical Co.,Ltd. 021-56795766 sales@worldyachem.com China 9475 58
Shanghai Na Qian Chemical Technology Co. Ltd. 13598610367 13598610367 2841375912@qq.com China 3775 52
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
SPIRO PHARMA eric_feng1954@126.com China 9239 55
Suzhou JingTong Pharmaceutical Co., Ltd. 13675155016 tongtf110@sina.com China 963 55
Shanghai SuperLan Chemcial Technique Centre 0-2022843681 15618226720 chaolaichem@foxmail.com China 9996 58
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Energy Chemical 61
Cochemical Ltd. 58
Shanghai Worldyang Chemical Co.,Ltd. 58
Shanghai Na Qian Chemical Technology Co. Ltd. 52
Cool Pharm, Ltd 58
SPIRO PHARMA 55
Suzhou JingTong Pharmaceutical Co., Ltd. 55
Shanghai SuperLan Chemcial Technique Centre 58
Amadis Chemical Company Limited 58

1-(1-bromoethyl)-4-fluorobenzene Spectrum

1-(1-bromoethyl)-4-fluorobenzene(65130-46-3)1HNMR

65130-46-3 (1-(1-bromoethyl)-4-fluorobenzene) Related Search:

(2-Bromoethyl)benzene N1-(2-Bromoethyl)-4-fluorobenzene-1-sulphonamide N1-(2-Bromoethyl)-4-fluorobenzene-1-sulfonamide 3-Fluorophenethyl bromide 1-(2-Bromoethyl)-4-fluorobenzene
(1-Bromoethyl)benzene

1of2

4-FLUOROPHENETHYL BROMIDE 4-FLUORO-1-(2-BROMOETHYL)BENZENE 1-FLUORO-4-(2-BROMOETHYL)BENZENE 2-(4-FLUOROPHENYL)ETHYL BROMIDE 1-BROMO-2-(4-FLUOROPHENYL)ETHANE 1-(1-Bromoethyl)-4-fluorobenzene 1-(4-Fluorophenyl)ethyl bromide 1-Bromo-1-(4-fluorophenyl)ethane 1-(1-Bromoethyl)-4-fluorobenzene, 1-Bromo-1-(4-fluorophenyl)ethane, 1-(4-Fluorophenyl)ethyl bromide 4-Fluoro-alpha-methylbenzyl bromide 1-(1-Bromoethyl) -4-fluorobenzene Benzene, 1-(1-bromoethyl)-4-fluoro- 65130-46-3 332-43-2 5130-46-3 C8H9BrFNO2S Halogenated Hydrocarbons Organic Building Blocks Building Blocks C8 Aryl Fluorine series