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4-AMINO-6-BROMO (1H)INDAZOLE

4-AMINO-6-BROMO (1H)INDAZOLE structure

CAS No.: 885518-50-3

Chemical Name:: 4-AMINO-6-BROMO (1H)INDAZOLE

Synonyms: 6-broMo-1H-indazol-4-aMine;4-AMINO-6-BROMOINDAZOLE;Indazol-4-amine, 6-bromo-;6-Bromo-1H-indazole-4-amino;6-Bromo-1H-indazol-4-ylamine;1H-Indazol-4-aMine, 6-broMo-;4-AMINO-6-BROMO (1H)INDAZOLE;4-AMINO-6-BROMO (1H)INDAZOLE ISO 9001：2015 REACH

CBNumber:: CB8286707

Molecular Formula:: C7H6BrN3

Molecular Weight:: 212.05

MDL Number:: MFCD07368220

MOL File:: Mol file

MSDS File:: SDS

Last updated:2026-05-28 03:35:48

Product description	Number	Pack Size	Price
4-Amino-6-bromo-1H-indazole Asreported	261439	250mg	$531
4-Amino-6-bromo-1H-indazole Asreported	261439	500mg	$744
4-Amino-6-bromo-1H-indazole Asreported	261439	1g	$1034
4-Amino-6-bromo-1H-indazole Asreported	261439	2g	$1451
4-Amino-6-bromo-1H-indazole Asreported	261439	5g	$2229

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4-AMINO-6-BROMO (1H)INDAZOLE Properties

Boiling point	426.5±25.0 °C(Predicted)
Density	1.867±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	14.39±0.40(Predicted)
Appearance	Yellow to brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P264-P271-P280-P302+P352-P304+P340+P312-P305+P351+P338-P332+P313-P337+P313-P362-P403+P233-P405-P501

4-AMINO-6-BROMO (1H)INDAZOLE price More Price(37)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	261439	4-Amino-6-bromo-1H-indazole Asreported	885518-50-3	250mg	$531	2026-06-03	Buy
Usbiological	261439	4-Amino-6-bromo-1H-indazole Asreported	885518-50-3	500mg	$744	2026-06-03	Buy
Usbiological	261439	4-Amino-6-bromo-1H-indazole Asreported	885518-50-3	1g	$1034	2026-06-03	Buy
Usbiological	261439	4-Amino-6-bromo-1H-indazole Asreported	885518-50-3	2g	$1451	2026-06-03	Buy
Usbiological	261439	4-Amino-6-bromo-1H-indazole Asreported	885518-50-3	5g	$2229	2026-06-03	Buy

Product number	Packaging	Price	Buy
261439	250mg	$531	Buy
261439	500mg	$744	Buy
261439	1g	$1034	Buy
261439	2g	$1451	Buy
261439	5g	$2229	Buy

4-AMINO-6-BROMO (1H)INDAZOLE Chemical Properties,Uses,Production

Uses

6-Bromo-1H-indazol-4-amine is used as a reagent in the synthesis of indazole derivatives as PI3 kinase inhibitors useful in the treatment of PI3 kinase-mediated diseases.

Synthesis

885518-46-7

885518-50-3

General procedure for the synthesis of 4-amino-6-bromo-1H-indazole from 4-nitro-6-bromo-1H-indazole: 4-nitro-1H-indazole (commercially available, CAS: 2942-40-7, 1.4 g, 8.26 mmol) or 6-bromo-4-nitro-1H-indazole (commercially available, CAS: 885518-46-7, 2.0 g, 8.26 mmol) in a round-bottomed flask containing ethanol (20 mL) and water (10 mL) as the solvent mixture. Ammonium chloride (221.5 mg, 4.13 mmol) was added and stirred for 5 min at room temperature. Subsequently, iron powder (Part I: 1.3 g, 23.46 mmol; Part II: 1.0 g, 17.86 mmol) was added in batches and stirred at 80 °C for 5 min and 20 min, respectively. Immediately after completion of the reaction, the reaction mixture was filtered and the filtrate was washed with ethanol (10 mL). The filtrate was concentrated under reduced pressure and then dissolved in ethyl acetate (8 mL). The organic phase was washed with brine, dried over anhydrous Na2SO4 and concentrated again. The resulting solid was purified by silica gel column chromatography using petroleum ether with ethyl acetate (8:1) as eluent to afford the target product 4-amino-6-bromo-1H-indazole (10a: 379.0 mg, 93% yield; or 10b: 1.62 g, 92% yield) as a yellow solid.

References

[1] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 23, p. 6194 - 6205
[2] Patent: CN107805221, 2018, A. Location in patent: Paragraph 0083; 0084; 0085; 0087
[3] Patent: CN108689937, 2018, A. Location in patent: Paragraph 0138; 0149; 0154; 0155; 0156
[4] Patent: WO2017/68064, 2017, A1. Location in patent: Page/Page column 186

4-AMINO-6-BROMO (1H)INDAZOLE Preparation Products And Raw materials

Raw materials

6-BROMO-4-NITRO-1H-INDAZOLE Ammonium chloride Ethanol Iron Water

Preparation Products

6-Bromo-1-methyl-1H-indazol-4-amine

4-AMINO-6-BROMO (1H)INDAZOLE Suppliers

Global( 91)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63645	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
career henan chemical co	+86-0371-86658258	factory@coreychem.com	China	29780	58
Career Henan Chemica Co	+86-0371-86658258 +86-13203830695	laboratory@coreychem.com	China	30203	58
KARMEL TECHNOLOGY (HK) CO.,LIMITED	+8618795957998	karmelhk@126.com	CHINA	2886	58
ANHUI WITOP BIOTECH CO., LTD	+8618071025641	eric@witopchemical.com	China	23506	58
Blocksynth Pharmaceutical Technology Co.,Ltd	0086-19817745290; 19817745290	bd@blocksynth.com	China	5971	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1059@dideu.com	China	29096	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 17705817739	info@dycnchem.com	China	52693	58
CR Corporation Limited		fred.wen@crcorporation.cn	China	8642	58

Supplier	Advantage
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Career Henan Chemica Co	58
KARMEL TECHNOLOGY (HK) CO.,LIMITED	58
ANHUI WITOP BIOTECH CO., LTD	58
Blocksynth Pharmaceutical Technology Co.,Ltd	58
Dideu Industries Group Limited	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
CR Corporation Limited	58

View Lastest Price from 4-AMINO-6-BROMO (1H)INDAZOLE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-11-18	4-AMINO-6-BROMO (1H)INDAZOLE 885518-50-3	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
	2020-01-05	4-AMINO-6-BROMO (1H)INDAZOLE 885518-50-3	$1.00	1KG	99%	200kg	Career Henan Chemical Co

4-AMINO-6-BROMO (1H)INDAZOLE
885518-50-3
$1.10
99.00%
Dideu Industries Group Limited

4-AMINO-6-BROMO (1H)INDAZOLE
885518-50-3
$1.00
99%
Career Henan Chemical Co

4-AMINO-6-BROMO (1H)INDAZOLE Spectrum

4-AMINO-6-BROMO (1H)INDAZOLE(885518-50-3)¹HNMR

885518-50-3(4-AMINO-6-BROMO (1H)INDAZOLE)Related Search:

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4-AMINO-6-BROMOINDAZOLE 4-AMINO-6-BROMO (1H)INDAZOLE 1H-Indazol-4-aMine, 6-broMo- Indazol-4-amine, 6-bromo- 6-Bromo-1H-indazol-4-ylamine 6-Bromo-1H-indazole-4-amino 4-AMINO-6-BROMO (1H)INDAZOLE ISO 9001：2015 REACH 6-broMo-1H-indazol-4-aMine 885518-50-3